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Tag: "interaction" at biology news

UCLA scientists discover immune response to HIV differs, even in identical twins

...ghly divergent. The finding, demonstrates that the interaction between their immune systems and the virus was random and unpredictable--indicating that a "one size fits all" vaccine may not be possible. "If the goal is to develop a vaccine, our findings suggestthis may not be so straightforward," said Dr. Otto ...

Scientists directly view immune cells interacting to avert autoimmunity

... supports one contending hypothesis: It is not the interaction between the two types of T cells, but rather the interaction of each with the dendritic cells that leads to protection from autoimmune assaults. Analyzing these...

UCLA imaging study of children with autism finds broken mirror neuron system

...ymptoms of autism include difficulties with social interaction -- including verbal and nonverbal communication -- imitation and empathy. The new findings dramatically bolster a growing body of evidence pointing to a breakdown of the brain's mirror neuron system as the mechanism behind these autism symptoms. "Ou...

Bird song changes sound alarm over habitat fragmentation

... say this change in song-sharing is due to lack of interaction between individuals isolated by habitat barriers. According to the study's authors, Dr Paola Laiolo and Dr José Tella of the Estación Biologica de Doñana in Seville, Spain: "We found that habitat loss in the steppe matrix markedly affected song-type...

Pregnancy drugs can affect grandkids

... say this change in song-sharing is due to lack of interaction between individuals isolated by habitat barriers. According to the study's authors, Dr Paola Laiolo and Dr José Tella of the Estación Biologica de Doñana in Seville, Spain: "We found that habitat loss in the steppe matrix markedly affected song-type...

Alcoholism, smoking and genetics among Plains American Indians

..."You've really got to look at the gene-environment interaction when you've got a gene like this, with two common variants." Furthermore, she said, researchers cannot extrapolate findings from one group to another. "The vast majority of alcoholism studies are conducted among male alcoholics, and also among trea...

Researchers reverse juvenile diabetes in animal model

.... This treatment strategy was found to inhibit the interaction and destructive effect of T cells on the insulin-producing beta cells of the pancreas, a process that is known to be a critical part of how diabetes occurs. Subcutaneous injection of dendritic cells into the abdominal/pelvic area near the pancreas a...

Light activated anticancer drug targeted to DNA using cisplatin like sub-units

...to light activated systems." Cisplatin begins its interaction with cancer DNA by binding to the nitrogen atoms of the DNA bases, typically guanine. Our new supramolecules use this nitrogen-binding site to hold the light activated drug at the target until signaled to activate. Thus the new supramolecules can be ...

Flesh-eating bacteria escape body's safety net

...l, San Diego. The UCSD investigators examined the interaction of Strep bacteria with neutrophils, specialized white blood cells that play a front line role in human's immune defense against pathogenic microbes. Recent research by European investigators had shown that neutrophils are particularly effective defe...

Ernst Mayr's theory illustrated in genetic epidemiology studies

...interacted with one another, and that this genetic interaction in turn led to an interaction of natural selection with genetic drift that could cause genetic revolution ?new directions of evolu...

Driver of anthrax toxicity could lead to late-stage therapy

...e bacteria depends on separate complexes formed by interaction of a carrier protein, protective antigen, with lethal and edema factors responsible for the toxic effects and swelling that impairs the host's immune response. In the current study, the researchers inactivated genes randomly in human cells. They th...

GlycoFi announces the first production of antibodies with human glycosylation in yeast

...ty, therapeutic half-life, tissue distribution and interaction with complement proteins. Currently glycoproteins comprise about 70% of all approved therapeutic proteins and the therapeutic protein market is expected to grow at over 20% annually over the next decade. GlycoFi is now working to expand its library ...

Warming trend may contribute to malaria's rise

...ans to incorporate malaria data and to explore the interaction of various factors that may affect the spread of malaria. "I think it's reasonable to assume that these factors are not independent," Pascual said. "It's important to understand how they interact and also to see if we can determine their relative i...

UCSD biologists find new evidence for one-way evolution

... of complex traits, which result from the combined interaction of several genes, is an old and at times controversial scientific question. While the late evolutionary biologist Stephen Jay Gould popularized the hypothesis of irreversibility, known as Dollo's Law, studies that use current methods to reconstruct t...

Aggression-related gene weakens brain's impulse control circuits

...ikely to contribute only a small amount of risk in interaction with other genetic and psychosocial influences; it won't make people violent," explained Meyer-Lindenberg. "But by studying its effects in a large sample of normal people, we were able to see how this gene variant biases the brain toward impulsive, a...

Viral protein helps infected T cells stick to uninfected cells

...y, but, in this case, the virus is stimulating the interaction with other T cells rather than a normal immune response." HTLV-1 infects an estimated 15 to 25 million people worldwide. About 5 percent of those infected develop adult T cell leukemia or lymphoma (ATLL), an aggressive disease characterized by a lo...

New cellular flaw found in some virulent breast cancers

...arber Cancer Institute have identified a molecular interaction that triggers a particularly aggressive form of br... Sicinski, MD, PhD, of Dana-Farber report that the interaction of a certain mutated oncogene and the newly described growth control flaw is seen in about 10 percen...

Formation of cellulose fibers tracked for the first time

...hase and microtubules, but the exact nature of the interaction was hard to pinpoint," Ehrhardt said. "The microtubules act as more than a general scaffold for organizing the cell wall; individual elements of the microtubule array appear to actively direct the pattern of the cellulose fibers. This work should set...

Protein 'nanosprings' most resilient found in nature

...repeats are one of the most common protein-protein interaction motifs in nature. Ankyrin repeats of varying lengths appear in more than 400 human proteins expressed in many tissues, Bennett said. For example, ankyrin repeats are found in association with specialized hair cells of the inner ear, where they play ...

U of MN researchers develop way to visualize synchronized interactions of nerve cells in the brain

... during a short period of time. They studied this interaction in research subjects who looked at a spot of light. Georgopoulos used MEG data from 248 sensors to detect the changing interactions over time. The measurements they recorded represent the workings of tens of thousands of brain cells. The large am...

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