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Tag: "interaction" at biology news

The making and breaking of microtubules

... the subunits are straight enough to allow lateral interaction between growing protofilaments. Says Nogales, "Such contacts appear semiconserved with respect of those previously seen in microtubules, and suggest a mechanism by which microtubules will first grow into open sheets that are able to quickly 'zip' int...

Mosaic mouse technique offers a powerful new tool to study diseases and genetics

...n, and their final function is determined by their interaction with other neurons," Luo says. "But we found that there appears to be a certain degree of predisposition to these cells by their lineages. This comes back to an interesting problem in developmental neurobiology as to whether the brain is wired by gen...

To translate touch, the brain can quickly rearrange its sense of the body

...ely perceive the external world through our body's interaction with it and also to produce a coherent sense of self. Because all these signals carry such different kinds of information, the brain must perform a constant juggling act in order to make sense of the body and the world. In the new study, the researc...

Self-assembled DNA buckyballs for drug delivery

...tructure arranged so that DNA would have a maximum interaction with water and polystyrene would avoid water as much as possible. Other researchers have used other amphiphiles to make spheres, rods and other solids. The hollow buckyballs were an intriguing and serendipitous surprise. A model suggests that one buc...

The genetic origins of corn on the cob

...ons for selecting an unbranched ear, including the interaction with other genes that were subsequently lost during domestication, but we don't yet know if this is the case." The study reveals that plants with more ramosa1 activity (e.g. typical corn) tend to have fewer branches, shorter branches, and fewer flow...

$6.5 Million Grant for Microarray Center at Yale School of Medicine

...ons for selecting an unbranched ear, including the interaction with other genes that were subsequently lost during domestication, but we don't yet know if this is the case." The study reveals that plants with more ramosa1 activity (e.g. typical corn) tend to have fewer branches, shorter branches, and fewer flow...

Novel plague virulence factor identified

...rium that causes plague. They also showed that the interaction between Y. pestis and the worm is quite similar to what occurs in mammals, including humans. The work indicates that the pathogen may use similar virulence mechanisms to infect evolutionary disperse organisms. These findings are important, the resea...

New Look at DNA Hints at Origin of UV Damage

...rium that causes plague. They also showed that the interaction between Y. pestis and the worm is quite similar to what occurs in mammals, including humans. The work indicates that the pathogen may use similar virulence mechanisms to infect evolutionary disperse organisms. These findings are important, the resea...

New protein vital for immune response is found in surprise location

...he virus and binds to viral genetic material. That interaction starts a cascade of biochemical reactions that eventually triggers the cell to make a protein called interferon, which in turn fights off the virus. But the chain of events between RIG-I's encounter with the virus and the interferon response is not...

Pinpointing the cause of a neurodegenerative disorder

... flies. The researchers then showed that the same interaction and pathological effects occurred in mice -- in which Ataxin-1 affected the mammalian version of Senseless, which is called GFi-1. And, they found that mice lacking GFi-1 showed Purkinje cell degeneration, just like humans with SCA1. "The overall pi...

Snapin: A protein with therapy potential for autism

...npointing a drug target where one can regulate the interaction of snapin with cypin," Firestein explained. Both of these proteins have many other functions in the nerve cell environment and elsewhere in the body. "We need to change cypin's function for branching but not its other functions," Firestein said. "Ra...

New lead reported in tumor angiogenesis

...e started to think that it must involve the direct interaction between the tumor and endothelial cells." Wang sa...o increase, leading to a direct surface to surface interaction between the tumor and endothelial cells." Wang's hunch also made good intuitive sense for another r...

Public collections of DNA and RNA sequence reach 100 gigabases

...nt databases began collaborating very early on, an interaction that was initiated by Greg Hamm, the EMBL Data Library's first employee. Staff at the two databases, which at that time had to find sequences in published journal articles and re-key them into the databases, allocated journals to each team to avoid d...

Hide and seek: Researchers discover a new way for infectious bacteria to enter cells

... invasion strategy, which they knew depended on an interaction between a protein on the surface of the bacteria, known as InlB, and a protein called Met on the surface of the cell it was invading. They discovered that when InlB interacts with Met, the cell responds by adding a chemical tag to Met that flags i...

Gene discovery sheds light on causes of rare disease, cancer

... invasion strategy, which they knew depended on an interaction between a protein on the surface of the bacteria, known as InlB, and a protein called Met on the surface of the cell it was invading. They discovered that when InlB interacts with Met, the cell responds by adding a chemical tag to Met that flags i...

Physical and functional interaction of key cell growth molecules linked to cancer

... to have a major role in oncogenesis. Importantly, interaction with STAT3 provides a mechanism for EGFR-driven re...he researchers also discovered that the EGFR/STAT3 interaction leads increased expression of inducible nitric oxide synthase (iNOS). Although elevated iNOS is also...

Researchers create infectious hepatitis C virus in a test tube

...led E2, binds to CD81, and they believed that this interaction is necessary for the virus to bind to target cells. The Rockefeller researchers showed that CD81 molecules that are not attached to the surface of host cells compete with membrane-bound CD81 and inhibit entry of HCV into the cell. They also showed t...

Primate virus jumps species barrier to humans for first time in Asia

...ngton, and a co-author on the study. "Interspecies interaction there is very different, and rates of human-monkey contact are much lower." Limiting dangerous contact between primates and humans can have other benefits, as well, such as reducing the transmission of human infections to monkeys. Human measles, for...

How cell suicide protects plants from infection

... by several research groups. His group studies the interaction between plants and viruses using tobacco as a model system. They identified and silenced a "pro-survival" gene, BECLIN-1, that is important in the PCD response. When BECLIN-1 is active, infection is localized to a small number of cells that later di...

Opiates Better Than Sedatives For Treating Newborns In Withdrawal

... in assessment of the quality of the mother-infant interaction in a supervised environment." ...

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