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Tag: "interaction" at biology news

UNC launches study of liver injury caused by drugs

...ceptibility to the many diseases that represent an interaction with the environment." ...

Shutting down the HIV assembly line

...f identifying compounds that inhibit this Gag-AP-3 interaction and that may lead to new efforts to treat HIV infe...e said, since it should be possible to block Gag's interaction with AP-3 without disrupting AP-3 function in the cell. And by targeting an early step in HIV partic...

At long last, scientists figure out how plants grow

..., thereby turning on the repressed gene. "The key interaction is between TIR1 and the repressor," Estelle said. ...s able to get that to work in a test tube, but the interaction would only occur if he added auxin to the solution." Auxin may stick around awhile, but it is event...

MUHC scientists describe genetic resistance to rampant virus

... new mechanism of resistance to CMV, involving the interaction between two genes. One gene flags virus-infected cells for destruction, the other gene allows our Natural Killers cells to recognize and terminate them. "This is a new concept in natural disease resistance," notes Dr. Vidal. "Our research suggests th...

Successful Test Of Single Molecule Switch Opens The Door To Biomolecular Electronics

...periments didn’t attempt because of the problem of interaction between the solution and the electrodes. “Almost everything we know about charge transfer in molecules is based on measurements made with the molecules suspended in solution,?Lindsay says. “Chemists have understood for a while that the solvent itsel...

Future diabetes drugs may target new protein interaction

...ing problem in people with diabetes, the proteins' interaction might be a target for future drugs to fight the di...th many different proteins, and it's just this one interaction you would want to prevent." But, he says, PGC1 has an unusually close relationship with sirtuin1 th...

PHACCS, an online tool for estimating the structure and diversity of uncultured viral communities using metagenomic information

...ing problem in people with diabetes, the proteins' interaction might be a target for future drugs to fight the di...th many different proteins, and it's just this one interaction you would want to prevent." But, he says, PGC1 has an unusually close relationship with sirtuin1 th...

Computational verification of protein-protein interactions by orthologous co-expression

...ing problem in people with diabetes, the proteins' interaction might be a target for future drugs to fight the di...th many different proteins, and it's just this one interaction you would want to prevent." But, he says, PGC1 has an unusually close relationship with sirtuin1 th...

Eliminate Data Analysis Bottlenecks in Drug Discovery

...ing problem in people with diabetes, the proteins' interaction might be a target for future drugs to fight the di...th many different proteins, and it's just this one interaction you would want to prevent." But, he says, PGC1 has an unusually close relationship with sirtuin1 th...

How A Latent Virus Eludes Immune Defenses

...s show that the amino acid element limits EBNA-1’s interaction with T cells by inhibiting synthesis and, to a lesser degree, degradation of the protein. How this evasive action works or helps the virus in a living organism is not entirely clear. But if T cells aren’t presented with bits of viral protein, they ha...

Touching Molecules With Your Bare Hands

...s show that the amino acid element limits EBNA-1’s interaction with T cells by inhibiting synthesis and, to a lesser degree, degradation of the protein. How this evasive action works or helps the virus in a living organism is not entirely clear. But if T cells aren’t presented with bits of viral protein, they ha...

At the molecular level, the predator is the prey

...granulosa newts and T. sirtalis garter snakes, the interaction has gone far beyond that simple fangs-off arrangement, evolving into a lethal contest of toxification/detoxification one-upsmanship. "One might think that this sort of change in the sodium channel would be too costly to the snakes," said Utah State ...

B cells are required for development of epithelial cancer associated with chronic inflammation

...inflammation. Previous studies have implicated an interaction between adaptive immune cells, like B lymphocytes, and innate immune cells during chronic inflammatory diseases. Dr. Lisa M. Coussens and colleagues from the Cancer Research Institute at the University of California at San Francisco used a mouse mode...

Virologists make major step towards understanding the process of HIV infection

... and appended to the desired site. To observe the interaction of HIV with the host cell, there had also been attempts to label the virus with GFP. However, the genetic modifications impaired the formation of virus particles or their infectiousness, thus limiting the value of results obtained. A team of Heidelbe...

New Species of Coral Discovered Off Southern California

... and appended to the desired site. To observe the interaction of HIV with the host cell, there had also been attempts to label the virus with GFP. However, the genetic modifications impaired the formation of virus particles or their infectiousness, thus limiting the value of results obtained. A team of Heidelbe...

Scientists find viruses can't stick to sea bugs in the dark

...t environmental factors of the phage-cyanobacteria interaction is vital," says Ying Jia. Cyanophages may be an important weapon against problematic algal blooms. On hot, sunny days algae can cause massive, toxic blooms, poisoning huge areas of the sea with their waste products and killing fish, sea mammals such...

Determining The Fate Of Cells In The Human Body

...na University School of Medicine, investigated the interaction of proteins responsible for Saethre-Chotzen Syndrome, a rare genetic disorder associated with limb abnormalities including webbed fingers and other developmental defects. In the study, Dr. Firulli and colleagues studied how two proteins, Twist1 and ...

New miniaturised chip dramatically reduces time taken for DNA analysis

...chemically interacting with it and converting this interaction into an electrical current that they measure. To detect DNA, the new miniaturised electrochemical genosensors have a probe containing DNA fragments that complement the DNA they aim to detect. For example, to detect Salmonella in a sample of mayonnai...

U of T researchers map role of Epstein-Barr virus in cancer

...l regulation by binding to USP7 and preventing its interaction with the p53 protein. "Normally, p53 levels will increase in response to certain problems in the cell such as damaged DNA and this stops the cell from proliferating. Through binding USP7, EBNA1 keeps the p53 levels low so cells will continue to divi...

Malaria mechanism revealed

...ake. This finding suggested that the RII handshake interaction serves to clamp the parasite protein onto the glycophorin A receptor of red blood cells. An important idea stemming from this view is that blocking the RII interaction--with drugs or vaccines--should block glycophorin A receptor binding and forestall...

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