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Tag: "interacting" at biology news

When the going gets tough, slime molds start synthesizing

...hout nature. Organisms use chemicals as a means of interacting with their surroundings and mankind has exploited this fact to discover the vast majority of pharmaceuticals used to treat disease today. "The major fundamental question in our case is why do organisms make chemicals, what role do these molecules pla...

Chimpanzees can transmit cultural behavior to multiple 'generations'

...al group was allowed to observe the process before interacting with the testing box. Once the second animal succeeded, another chimpanzee would enter and observe the technique, and so on down the chain. In the two social groups trained to slide or lift the door, the technique used by the original animal was pass...

Genomatix technology facilitates de novo identification of new renal disease associated genes

...romoter structures which can be used to find novel interacting molecules. Here, these principles are applied to a set of genes linked to the unique functional unit of the glomerular slit diaphragm. An evolutionarily conserved promoter model was generated. Genome-wide scans using this promoter model effectively p...

Sex: It's costly but worth it. Just ask a microbe

...d out, some of those mutations reduced the cost of interacting with sexual partners. The downside is that the same mutations can also reduce their mating ability. "There is some kind of balance out there between the cost and benefit of sex," says Xu. "And we are looking into that right now". ...

'Genetic network' guards against lethal DNA damage

...h each other, he said. "This strategy for finding interacting genes will open the door to an extraordinarily rich source of new data on DNA damage, repair, and human diseases," Boeke added. ...

Chemical guidance of T cells leads to immunologic memory and long-term immunity

...t their ability to home in on the dendritic cells interacting with the helper T cells. The result was a marked impairment of memory cell generation. These new findings not only provide insight into the fundamental behavior of the immune system, but also suggest that attention needs to be paid to chemokines a...

In the mind's eye: How the brain makes a whole out of parts

...rld, so that we have the necessary information for interacting with our environment. "Vision doesn't happen in the eye," Connor said. "It happens at multiple processing stages in the brain. We study how objects are signaled or encoded by large populations of neurons at higher-level stages in the object-process...

Malaria parasites develop in lymph nodes

...e parasites appeared degraded. They were also seen interacting with key mammalian immune cells, suggesting that the immune cells were destroying them. A small number of the parasites in the lymph nodes, however, escaped degradation and began to develop into forms usually found only in the liver. Up to now, re...

Ernst Mayr's theory illustrated in genetic epidemiology studies

...However, simply by altering the frequencies of the interacting genes, the apparent importance of these two genes ...c system, and, depending on the frequencies of the interacting factors, some genes seem to play a larger role than others at any given time. "The real causation o...

HIV accessory protein disables host immunity via receptor-protein intermediary

.... "The glucocorticoid receptor-Vpr complex must be interacting with something else." The team, led by first author Muthumani Karuppiah, PhD, Senior Research Investigator, looked for molecules with which the glucocorticoid receptor-Vpr complex would bind and identified PARP-1, another protein that controls the...

Scientists directly view immune cells interacting to avert autoimmunity

... of the immune system involves multiple cell types interacting dynamically in three dimensions, which is very difficult to analyze in vivo -- and nearly impossible to authentically reproduce in vitro." The team of immunologists and diabetes researchers used the new microscope to show that when Treg cells are ab...

Dog genome sequenced

...s. They attribute the differences to at least two interacting loci, one of which is located on the X chromosome. "Sexual dimorphism seems to have evolved as females became smaller than males due to natural selection for optimal size," Lark explains. "This is consistent with our finding that a variant on the X ...

Scientists fetch useful information from dog genome publications

...s. They attribute the differences to at least two interacting loci, one of which is located on the X chromosome. "Sexual dimorphism seems to have evolved as females became smaller than males due to natural selection for optimal size," Lark explains. "This is consistent with our finding that a variant on the X ...

Researchers develop new method to help find deadly malaria parasite's Achilles heel

...to the Fields group's Plasmodium data, focusing on interacting proteins that have homologs in other species. While the genomes of hundreds of species are filled with homologous proteins, Ideker and his colleagues are eager to understand how they interact with one another as part of a new approach to help in the ...

Technique offers new view of dynamic biological landscape

...f antiviral drugs that target proteins produced by interacting genes. Such a strategy would help to prevent these... needed a way to quantify the epistatic effects of interacting mutant genes on the cells' viability. Since yeast form round colonies when grown in culture dishes, ...

How E. coli bacterium generates simplicity from complexity

...f the bacterium's genome is tightly organized into interacting networks involved in metabolism or regulation of gene activation, or transcription. These linked networks are devoted to sensing, ingesting, and degrading potential "food" in the form of sugars and other energy-rich organic molecules. E. coli must a...

Many needles, many haystacks

...ata, for example, 26 sets of proteins seemed to be interacting through linear motifs. "One challenge was to eliminate red herrings, which crop up everywhere when you look for very small patterns," Russell says. "The fact that nine of these motifs were already known was a sign we were on the right trail; we then...

Noise And Delays Explain Why Some Genes Oscillate In Activity

...aying music and videos, keeping the lights on, and interacting with them: all the annoyances that can also keep humans from sleeping. To determine the drug's effect on drowsy monkeys, Deadwyler and colleagues used a behavioral test called Match-To-Sample, which measured both accuracy of memory and speed of recal...

Clocking in Pillow Time without the Pillow

...aying music and videos, keeping the lights on, and interacting with them: all the annoyances that can also keep humans from sleeping. To determine the drug's effect on drowsy monkeys, Deadwyler and colleagues used a behavioral test called Match-To-Sample, which measured both accuracy of memory and speed of recal...

Model identifies genes that induce normal skin cells to become abnormal

...sional model that allows scientists to observe how interacting with the microenvironment of metastatic melanoma cells induces normal skin cells to become similar to aggressive cancer cells that migrate and spread throughout the body. The model, developed by Mary J. C. Hendrix and colleagues at Children's Memor...

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