Researchers reveal structure of protein altered in autism
... “Normally, individual neuroligins are encoded to interact with specific neurexin partners. The two partners are members of distinct families of proteins involved in synaptic adhesions, imparting ‘stickiness’ that enables them to associate so that synapses form and have the capacity for neurotransmission,” ...New findings challenge established views on human genome
...es of DNA sequences that do not code for proteins, interact in overlapping ways not yet fully understood. In a group paper published in the June 14 issue of Nature and in 28 companion papers published in the June issue of Genome Research, the ENCyclopedia Of DNA Elements (ENCODE) consortium, which is organiz...Research finds that circadian rhythms dominate all life functions
...etabolism is essential for understanding how genes interact with and regulate health and disease. Colorado State University researcher Andrey Ptitsyn's new analysis of data collected through several studies establishes a baseline oscillation in 98 to 99 percent of all genes through advanced computer algorithm...Revealed -- Mosquito genes that could be controlling the spread of killer viruses
...ch as possible about these genes, and the way they interact with specific pathogens, we hope to gain a more complete understanding of the mechanisms by which a pathogen either survives inside the insect body, or is killed by the insect’s defences.” The international research team, led by Imperial PhD stude...Genome of Clostridium botulinum reveals the background to world's deadliest toxin
...decaying animal materials in the soil, and doesn’t interact with human or other large animal hosts for prolonged periods of time. Occasionally it gets into a living animal, via contaminated food or open wounds, leading to infant botulism or wound botulism, both of which are serious human infections. The ho...New designer lipid-like peptide with lipid nanostructures for drug delivery systems
...stand the basic science of how lipid-like peptides interact with lipid molecules, but also may provide new strategies for the encapsulation and the delivery of biological active materials. They detailed their findings in the report on the impact of integrating short surfactant-like designer peptides in lipid...Protein enables discovery of quantum effect in photosynthesis
...hip. "It's taught us a lot about how chlorophylls interact with proteins. It was ideal for this study." Blankenship's colleague, Graham R. Fleming, Ph.D., Deputy Director of the U.S. Department of Energy's Lawrence Berkeley National Laboratory and professor of chemistry at the University of California, a...Nitric oxide: Key to cardiovascular and pulmonary function and drug effectiveness
...ed receptors reside on the cell surface where they interact with all manner of stimuli, including circulating factors such as adrenaline, as well such diverse sensory signals as odorants and light. The activation of these receptors leads to the propagation of intracellular signals. Once activated the receptor...Corals -- More complex than you?
...is, Prof. Miller believes, is that coral genes may interact with each other in far less complex ways. Humans, on the other hand, are the product of a continuous and complicated dialogue between thousands of genes. Who has the best formula for long-term survival remains unclear. Today’s corals first appear...DNA repair proteins monitored at double-strand break
...proteins, such as ATM, NBS1, XRCC4 and gamma-H2AX, interact to coordinate repair of double-strand breaks. For example, the investigators showed that NBS1 recruits ATM to the break; and that ATM and NBS1 cooperate to disrupt nucleosomes—the compact packages formed when strands of DNA wind around proteins, call...Uniform language for describing genes of pathogenic and beneficial microbes
...he goal of creating terms to describe how microbes interact with plants. However, we quickly realized that almost all the terms were relevant to microbes that interact with animals and humans, and the response from researchers that study human and animal diseases has ...Natural antibiotics yield secrets to atom-level imaging technique
...t, we need to understand how these AMP smart bombs interact with membranes to destroy bacteria. We need to know how they're shaped before, during and after the process of attaching to bacteria and how they attach." Solid-state NMR spectroscopy is an ideal tool for answering such questions because it provid...Technology reveals 'lock and key' proteins behind diseases
...ybrid system), scans cells to detect proteins that interact with key proteins called ATP-binding cassette (ABC...elicate membrane proteins. Simply, if two proteins interact in iMYTH, they will stain the yeast cell blue. "Like lock and key, if two proteins interact with one...New mechanism for nutrient uptake discovered
...e-like structures at the cell's surface physically interact to control the uptake of a vital nutrient, nitrogen. It is the first time scientists have found that the interaction of neighboring molecules is essential to this regulation. Since plants, animals, bacteria, and fungi all share similar genes for this...Researchers discover gene crucial for nerve cell insulation
...r gene disrupts the process by which several genes interact to create myelin, a fatty coating that covers nerve cells and increases the speed and reliability of their electrical signals. The discovery has implications for understanding disorders of myelin production. These disorders can affect the peripher...Climate change could trigger 'boom and bust' population cycles leading to extinction
...cal model that evaluates how climate and resources interact with populations, including a fine-grained analysis of impacts on juveniles, reproducing adults, and adults. In areas where climate change leads to more "good years," with the occasional poor year still occurring, populations will fluctuate dramat...New molecular pathway could reveal how cells stick together
...ysiology and development of organisms. Cells must interact with each other to produce system responses, like the remodeling of a tissue during development or for orchestration of an integrated immune response. One way they do this is by physically attaching to one another and to surfaces. Andrea Page-McCaw, ...Cancer tip -- Nanoparticles can damage DNA, increase cancer risk
...out how they behave in the environment or how they interact with and affect humans. "Unfortunately, only a very small portion of research on nanoparticles is focused on health and safety risks, or on threats to the environment," Pacheco said. "I am concerned because so many new nanoparticles are being de......ucleosomes in 3,692 promoters (regions of DNA that interact with regulatory factors to control gene activity) within seven human cell lines, including malignant melanoma. Nucleosomes are spherical packing units for DNA. They consist of a length of DNA wrapped around a core, like ribbon around a spool that ...