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Tag: "insulin" at biology news

Increased sensitivity to nerve signals keeps diabetes at bay

..., including impaired glucose tolerance and reduced insulin release, the authors report. M3 receptors are norm...site: a profound increase in glucose tolerance and insulin release, the researchers found. Moreover, such animals become resistant to developing symptoms of di...

New technology enables faster, more efficient cell harvest: Cell therapy meeting study

...injury and regenerate pancreatic tissue to produce insulin for people with diabetes. Regenerative medicine promises to improve health and quality of life by supporting and activating the body's natural healing abilities. ...

Embryos exposed in 3-D

...injury and regenerate pancreatic tissue to produce insulin for people with diabetes. Regenerative medicine promises to improve health and quality of life by supporting and activating the body's natural healing abilities. ...

Inheriting a tendency to brain infection

...gy for treatment, Casanova said. "It's like giving insulin to a diabetic patient," he said. "You just replace the missing compound." Soon, children who come into the intensive care unit with herpes simplex encephalitis may be treated with both the standard antiviral, acyclovir, and with type I interferon, ...

New biochip helps study living cells, may speed drug development

...which occur in muscles, neurons and the release of insulin from pancreatic cells. The chip currently can detect individual levels of different ions. Porterfield believes that with some modifications, however, the chip will be able to measure multiple ions at once and perform even more advanced functions ...

Insulin receptor stops progression of Alzheimer's disease

...imulation of a receptor in the brain that controls insulin responses has been shown to halt or diminish the n...nct from other types of diabetes. They showed that insulin and IGF-I receptors are produced separately in the brain, and begin to disappear early in Alzheimer'...

Buildup of damaged DNA in cells drives aging

...ular by genes that regulate the growth hormone and insulin pathways," said Laura Niedernhofer, M.D., Ph.D., assistant professor of molecular genetics and biochemistry, University of Pittsburgh School of Medicine, and first author of the study. How the researchers came to study the relationship between DNA...

New data from NIH lab confirms protocol to reverse type 1 diabetes in mice

... in situ hybridization (FISH), in combination with insulin staining, to follow the fate of male spleen cells transplanted into female recipients. The female mice that received male donor cells consistently showed Y-chromosome-positive insulin-producing islet cells, indicating that the introduced spleen cells...

Autoimmune disease triggered if T cells miss a single protein early on

...erson said. Immunologists have demonstrated that insulin is expressed in the thymus ?not just in the pancre...are protected from diabetes express high levels of insulin in the thymus, while those who are predisposed express lower levels of insulin in this organ. "Wha...

Proteins anchor memories in our brain

...erson said. Immunologists have demonstrated that insulin is expressed in the thymus ?not just in the pancre...are protected from diabetes express high levels of insulin in the thymus, while those who are predisposed express lower levels of insulin in this organ. "Wha...

Cardiologist's 'living chip' changes science of disease monitoring

... example, a wireless defibrillator/pacemaker or an insulin pump ?to take action to correct a detected abnormality. The device would communicate with the living chip in real time, making adjustments as a direct result of the chip's ability to detect changes. The company's molecular biology team is being led...

Molecular mechanism provides intra-cellular traffic signal

...ariety of human diseases. For example, problems in insulin secretion or presentation of insulin-receptors on the cell membrane result in diabetes. Defects in growth factor secretion and presentation of their receptors on cells result in cancer. Defects in neurotransmitter release or internalization result in...

Dragonfly's metabolic disease provides clues about human obesity

...estines may play in human metabolic disorders like insulin resistance, type-2 diabetes, and obesity. In mamm...has been shown to be related to the development of insulin resistance and metabolic disease in humans. "What's more, we could induce this activation in muscle...

Holiday gluttony can spell disaster for undiagnosed diabetics

...in-producing beta cells in the pancreas, requiring insulin to survive. This typically affects children. Type 2: The body can't efficiently use its own insulin and insulin production can't keep up with the high demand, so glucose builds up in the blood and the...

Replacing insulin is top-ranked breakthrough foreseen for health in developing world

Eliminating the need for costly insulin injections for diabetics, regenerating heart muscl...he study placed atop their list: "Novel methods of insulin replacement and pancreatic islet cell regeneration for diabetes." Many panellists noted the heavy...

From managing sugar to managing healing

...alifornia, Riverside, recently found that applying insulin directly to skin wounds significantly enhanced the...ocess. Skin wounds in rats treated topically with insulin healed faster"surface cells in the epidermis covered the wound more quickly and cells in the dermis,...

Studies find general mechanism of cellular aging

...eatic islet cells. Islet cells are responsible for insulin production and secretion. Because p16INK4a stops cancer cells from dividing and demonstrates increased expression with age, the scientists suspected the gene played a similar role in aging. The researchers developed strains of mice that were either d...

Diabetes slows nerve recovery after heart transplant

...t occurs when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces. Such a deficiency results in increased concentrations of glucose (sugar) in the blood, ...

Single molecule extends fat mice lives by reversing gene pathways associated with disease in obese

...e mice treated with resveratrol, such as increased insulin sensitivity, decreased glucose levels, healthier h...umans, high calorie diets can increase glucose and insulin levels leading to diabetes, cardiovascular disease, and non-alcoholic fatty liver disease. In the H...

'Exercise pill' switches on gene that tells cells to burn fat

...fat in the blood, heart disease, and resistance to insulin and diabetes. Dr. Evan’s Experimental Biology presentation on April 30 is part of the scientific program of the American Society for Biochemistry and Molecular Biology. This chemical switch is not the first success Dr. Evan’s laboratory has h...

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