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Tag: "insulin" at biology news

Scientists find that protein controls aging by controlling insulin

...ted insulin, because making an animal resistant to insulin increases its lifespan ?a phenomenon found in anim.... The mice with higher levels of Klotho had more insulin in their system than the normal mice, suggesting that the Klotho mice were resistant to insulin; the...

Insulin pulses keep the liver lean

... of Cell Metabolism. The newly discovered role for insulin may explain how an organ frequently flooded with t... bloodstream and burn it for energy. In the liver, insulin promotes the synthesis and storage of lipids and carbohydrates and blocks their breakdown and releas...

Fruit fly studies open new window on cancer research

...tumours. This research tells us more about the way insulin works and so it is furthering our understanding of processes associated with diabetes as well as cancer. We're fortunate that there are a number of groups with clinical interests in these areas in close proximity to us, which should help us assess t...

Malfunctioning bone marrow cells sabotage nerve cells in diabetes

Malfunctioning bone marrow cells that produce insulin appear to cause a dangerous nerve condition called...ues found that the bone marrow cells that produced insulin adversely affected nerve cells or neurons. "In our latest studies, we were surprised to discover t...

Energy management in cells may hold key to cancer defense

...regulation, the enzyme also responds to changes in insulin or glucose and mediates impaired energy metabolism, a hallmark of type 2 diabetes. "This indicates that AMPK is a very tempting target for the treatment of some forms of diabetes and even obesity," said Witters. As Witters' laboratory continues to ...

UCSD study clarifies insulin's role in blocking release of energy in patients with type II diabetes

... Institute investigator, found that high levels of insulin can block stress hormones known as catecholamines,...olism to occur, the body needs a balanced input of insulin and catecholamines. One of the actions of insulin --, the main energy storage hormone, is to block a...

Life-extending protein keeps blood sugar in check

...creas have improved glucose tolerance and enhanced insulin secretion in response to glucose. Glucose is the p... "The mice respond fast to high glucose by raising insulin levels, clearing the blood of the circulating sugar." "Under normal feeding conditions, when glucos...

Sea Ice May Be on Increase in the Antarctic

...creas have improved glucose tolerance and enhanced insulin secretion in response to glucose. Glucose is the p... "The mice respond fast to high glucose by raising insulin levels, clearing the blood of the circulating sugar." "Under normal feeding conditions, when glucos...

Weight control protein may yield antiobesity drugs

...od glucose; mice deficient for the protein develop insulin resistance and type 2 diabetes, they found. The c...ugs that mimic or enhance SH2-B action may improve insulin and leptin sensitivity and have potential value in treatment of obesity and type 2 diabetes," he add...

The making of a fat cell

...haracterized by other metabolic disorders, such as insulin resistance, he added. The generation of fat begins before birth and continues throughout life. The first step in fat production involves proliferation of mesenchymal stem cells, followed by differentiation into fat cell precursors called preadipocyt...

System Drastically Cuts Down Botulism Detection Time

...haracterized by other metabolic disorders, such as insulin resistance, he added. The generation of fat begins before birth and continues throughout life. The first step in fat production involves proliferation of mesenchymal stem cells, followed by differentiation into fat cell precursors called preadipocyt...

Short-term Bio Sensors Monitor From Afar

...haracterized by other metabolic disorders, such as insulin resistance, he added. The generation of fat begins before birth and continues throughout life. The first step in fat production involves proliferation of mesenchymal stem cells, followed by differentiation into fat cell precursors called preadipocyt...

Key To Stem Cell Transplant Success Is Tricking Immune System

...haracterized by other metabolic disorders, such as insulin resistance, he added. The generation of fat begins before birth and continues throughout life. The first step in fat production involves proliferation of mesenchymal stem cells, followed by differentiation into fat cell precursors called preadipocyt...

Discarded placentas deliver researchers promising cells similar to embryonic stem cells

...tem, and pancreatic cells with genetic markers for insulin and glycogen production. "In this first paper we sought to determine if amniotic epithelial cells have the potential to differentiate into many different cell types rather than focusing on ways for optimizing this potential for a specific cell type....

Tiny roundworm's telomeres help scientists to tease apart different types of aging

...y playing a role in the other half of aging is the insulin signaling pathway, proper mitochondrial function and dietary restriction," he reasons. Several types of cells in our body, such as mature nerve cells in the brain, oocytes, skeletal and heart muscle cells don't actively divide but stay put just like...

New cell transplantation technique restores insulin production in diabetics

...tation technique to restore the cells that produce insulin in patients with type 1 diabetes. The method is mi...s so that the new, healthy islet cells can restore insulin production, essentially stopping the progression of the disease. The study included 13 patients with...

Researchers find gland that tells fruit flies when to stop growing

...ntists found they could use the pathway that sends insulin to a fly's cells to genetically manipulate the siz... a fly's weight. Enlarging the gland by increasing insulin signaling triggered metamorphosis at smaller sizes than usual. Suppressing the gland's growth by dec...

MicroRNA gene that regulates lifespan found by Yale scientists

...ms that these genes regulate are modulated through insulin signaling, demonstrating the connection between insulin-driven metabolism and aging. "This microRNA is conserved in humans leading to the enticing idea of being able to beneficially affect the results of aging including diseases of aging," said Sla...

Software might revolutionize glucose monitoring in critically ill patients

...vels isnecessary to avoid stress hyperglycemia, an insulin resistancecondition that causes glucose levels to ...itors glucose levels and recommends theappropriate insulin pump rate and the time at which the next bloodsample should be taken, and indicates situations in wh...

New technique helps researchers determine amino-acid charge

... linked to such problems as hypertension, abnormal insulin secretion, abnormal heart conditions and brain seizures. As a result, these membrane proteins are often targeted by drug treatments. Previous approaches didn't provide sufficient resolution to let researchers accurately detect the association and di...

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