insights 2 7

Tag: "insights" at biology news

The closest look ever at the cell's machines

...al techniques were developed at EMBL that gave new insights into the dynamic nature of protein complexes. In c...ry successful, she says, producing fundamental new insights in how molecules are organised and contributing to Cellzome's success in complex and pathway analysi...

Bringing the zoos to the zebras

...ity members revealed that these data are providing insights into the effective conservation of Grevy's zebras and leading to important changes in community attitudes. "After the first year we showed them that only about 35 percent of their sightings of Grevy's zebras were in the presence of livestock, and t...

Study suggests that publicly available genome data may contain small but significant errors

...ailable sequence assembly, the new method provides insights into the difficulties of establishing a canonical and accurate sequence or physical map, and suggests ways that the two types of data can be combined to render increased confidence levels of the assembly. This physical mapping technology is simpl...

Ancient DNA provides clues to the evolution of social behavior

...the past. With this information, she hopes to gain insights into the way current global warming trends will affect rare and threatened species, such as the colonial tuco-tuco. ''What better way to understand how tuco-tuco populations respond to environmental changes than to look at 10,000 years of their hist...

International HIV/AIDS trial finds continuous antiretroviral therapy superior to episodic therapy

...ill analyze the SMART study data in detail to gain insights into the reasons for the increased risk. "SMART is one of the largest HIV/AIDS treatment trials ever conducted," notes NIAID Director Anthony S. Fauci, M.D. "The study reflects an extraordinary global collaboration among hundreds of dedicated AIDS c...

'Nano-keys' bind cell receptors and trigger allergic reactions

.... One day, Baird said, scientists might use these insights to develop new drug therapies for allergies and other immune responses, high cholesterol and perhaps viral infections. By understanding a membrane's role in cell function, she explained that these nano-keys could interfere with responses via the mem...

Mouse to man: The story of chromosomes

...hromosome 17 and mouse chromosome 11 offers unique insights into the evolution of the genome of higher mammals, said a Baylor College of Medicine researcher who participated in this effort reported in today's issue of the journal Nature. The work represents the first time that a mouse chromosome has been co...

On a fly's wing, scientists tally evolution's winners and losses

...hromosome 17 and mouse chromosome 11 offers unique insights into the evolution of the genome of higher mammals, said a Baylor College of Medicine researcher who participated in this effort reported in today's issue of the journal Nature. The work represents the first time that a mouse chromosome has been co...

Molecule by molecule, new assay shows real-time gene activity

... new technique could provide us with unprecedented insights into gene expression and many other fundamental biological processes in living cells." The central dogma of molecular biology holds that DNA is transcribed into mRNA, which is then translated into proteins. But several technical hurdles have hampered...

Multi-million pound UK Biobank underway

...oject that holds out real hope for producing vital insights into some of the most distressing diseases of middle and old age. It has already taken several years of careful planning and it now needs two to three thousand people to help us with this initial start-up phase. Because of UK Biobank's importance for...

Molecule does more than slice and dice RNA

...to control critical events of development. The new insights arise from the first clear molecular images of the structure of Dicer, an enzyme that enables cells to dissect genetic material precisely. The finding, which is reported in the January 13, 2005, issue of the journal Science by an HHMI research team ...

Advanced genomics and proteomics improve the diagnosis and treatment of a deadly lung disease

...to control critical events of development. The new insights arise from the first clear molecular images of the structure of Dicer, an enzyme that enables cells to dissect genetic material precisely. The finding, which is reported in the January 13, 2005, issue of the journal Science by an HHMI research team ...

Key heart and Alzheimer's disease protein imaged for first time in native state

...ipid-bound state will inevitably lead to even more insights into its role in cardiovascular and neurological disease in the years to come." ...

UCSD team unmasks family of immune system invaders

... and diverse expertise of many scientists." Their insights into the mechanisms of bacterial pathogens could lead to novel treatments for diseases such as dysentery. These findings may prove to be especially helpful in fighting bacterial disease in Third-World countries, in children and those with suppressed...

High resolution 'snapshots' detail dynamics of a cocaine antibody

...eviously took billions of years. "The structural insights into antibody catalysis that we have shown with 7A1 Fab' are critical for any future improvement of effective biocatalysts," Zhu said. "One of the main goals of our lab has been to focus on catalytic antibodies that will have a direct impact on publi...

Novel method reveals how menthol discovery could point towards new or improved pain therapies

...thol activity. Our experiments yielded significant insights into the functional elements of TRPM8 ion channel protein that would have been difficult to obtain using other mutagenesis methods." Because the methodology can be used to screen for activation or inhibition, Bandell added, it could prove to be us...

Outsmarting the smartie bug

...umococcus and is also going to give us fascinating insights into the evolution of the amazing diversity of capsular genes that can be produced by this pathogen" Researchers are at pains to point out that current vaccines are enormously successful and vaccination plays an essential in protecting all of us. Th...

Mice with glowing hearts shed light on how hearts develop

... time they beat. The development gives researchers insights into how hearts develop in living mouse embryos an... normally within the host heart, which could offer insights for heart repair. In the study, the mouse was engineered to express a specially designed molecule t...

Genome changes tracked during multiple myeloma initiation, progression and treatment

...of Cancer Cell, provide new genetic and biological insights that open innovative directions for the discovery of effective therapeutics that can be targeted to specific MM patients based on genetic perturbations known to contribute to MM pathogenesis. Although genetic screening studies have provided some ins...

Protein found to control tumor growth in certain breast cancers

... The evidence uncovered in this study provides new insights into the physiological functions of Nod1 and supports our contention that there is a clear link between Nod1 and estrogen sensitivity in these cells. Our future studies will assess the relationship between the pathway uncovered in breast cancer and o...

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