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Tag: "insights" at biology news

New study shows patients more willing to consider self-injectable HIV therapy than many physicians anticipate

...of Brighton and OpenMind study author. "These new insights from the OpenMind study will enable us to develop tools to facilitate more informed decisions by both patient and physician." The study also shows that physicians' own experiences and attitudes towards self-injection are a significant motivator for...

Scientists move forward understanding of schizophrenia

... "Mental illness remains a scourge of society. Our insights into the important role that the proteins PDE4B and DISC1 may play in the mis-function of the brain that leads to schizophrenia will lead our thinking in the development of new treatments for this disorder" ...

Science's Breakthrough of the Year: Watching evolution in action

...science society. In 2005, scientists piled up new insights about evolution at the genetic level and the birth...tron Stars: In 2005, new instruments yielded vivid insights into the most violent behaviors of neutron stars. A short, intense pulse of radiation from near the ...

Model identifies genes that induce normal skin cells to become abnormal

...issue of Cancer Research. "Our findings offer new insights into the influence of the tumor cell microenvironment on the transformation of normal skin cells, as well as on genetic triggering mechanisms and signaling pathways that could be targeted for novel therapeutic strategies to inhibit the spread of mela...

Zooming in on the protein-conducting channel

...embranes, said Frank. “Now that we have these new insights into the architecture of the PCC in its translocating, and possibly non-translocating state, we can explore the mechanisms of perpendicular versus lateral transport,?Frank said. ...

Novel protein complex enables survival in hostile environment

...otes, said: "This original work provides important insights into the evolution of the methanogens. These organisms have often been thought to be very limited in their metabolic capabilities. The current study goes a long way to dispelling this simplistic view and greatly extends our knowledge of their versati...

Phenotype is influenced by nature, nurture and noise

...tic regulation within single cells may lead to new insights about variability at the level of a fly, cat, or human." Changes in a cell's phenotype may be triggered by environmental factors, by programmed genetic instructions, or more subtly by built-in delays in biochemical pathways that generate oscillation...

Image of myosin-actin interaction revealed in cover story of Molecular Cell

...ks" along other proteins, revealing new structural insights that advance the current model of protein motility and muscle contraction. The culmination of four years of work, this collaboration among biochemists and structural biologists was selected as the cover story for the September issue of the scientifi...

NIH launches comprehensive effort to explore cancer genomics

...D. "This atlas of genomic changes will provide new insights into the biological basis of cancer, which in turn...s have provided the tools necessary to produce new insights into how and why genetic changes cause cancer. The Human Genome Project, an international effort led...

Gene expression profile helps predict chemotherapy response in ovarian cancer patients

...ncer, and could eventually provide clinicians with insights into the mechanisms of drug resistance. "In many patients with advanced ovarian cancer, post-operative treatment with first-line chemotherapy will result in an excellent clinical response," says senior author Stephen A. Cannistra, MD, director of gy...

How the neuron sprouts its branches

Neurobiologists have gained new insights into how neurons control growth of the intricate t...that constitute the brain's circuitry. Such basic insights into neuronal growth will help researchers better understand brain development in children, as well ...

Technique offers new view of dynamic biological landscape

... humans. In addition to offering important basic insights into the roles of proteins and genes, E-MAPs will also contribute to understanding evolutionary processes. "In evolutionary theory, the structure of epistatic gene interactions is critical," he said. "To understand how different variations, or allele...

Scientists crack code for motor neuron wiring

...iphering the entire Hox code could provide crucial insights into the organization of the complex circuitry that the spinal cord uses to control muscle action. Speculation aside, Jessell is optimistic that there will eventually be clinical value in deciphering the Hox code. "In developing ways to recover from...

'Computer-chemistry' yields new insight into a puzzle of cell division

...cers, said the researchers. Significantly, their insights arose not just from meticulous biochemical studies, but also from using sophisticated simulation techniques to perform "chemistry in the computer." In a paper published Nov. 24, 2005 online in the journal Biochemistry, members of the interdisciplina...

Animal models show that anabolic steroids flip the adolescent brain's switch for aggression

...inally, researchers such as Melloni hope these new insights can lead to treatments for aggressive behavior, with or without steroid abuse. "Linking aggression to fluctuations in vasopressin makes it an important neurotransmitter to target for pharmacotherapy," he says. ...

Tiny polyps gorge themselves to survive coral bleaching

...xperiments on coral reefs in Hawaii , provides new insights into how these tiny animals face a multitude of environmental threats. The report by Ohio State University researchers is published in the current issue of the British journal Nature. During the past decade, reports have multiplied of major bleachi...

Great (taste) expectations: Study shows brain anticipates taste, shifts gears

...depression and anxiety disorders, the new detailed insights into the power of anticipation could lead to better treatments for such conditions. "The placebo operates through expectancy. In this study, we've taken the pill out of the picture. We're just manipulating expectancies," he says. "The results beg th...

UCLA scientists find male gene in brain area targeted by Parkinson's

...linked to the onset of Parkinson's and could offer insights into who is at risk for the disease. "SRY may serve as a protective agent against Parkinson's," he said. "Men who contract the disease may have lower levels of the gene in the brain." Because SRY is found only in males, Vilain thinks women must pos...

High-tech tags on marine animals yield valuable data for biologists and oceanographers

...y," he said. The researchers are also gaining new insights into the lives of California sea lions, said Michael Weise, a graduate student working with Costa on the sea lion studies. "This technology brings a whole new dimension to our understanding of how California sea lions are using their environment," W...

Activation of a protein solidifies fear memory in the brain

...ng these molecular mechanisms may provide critical insights into psychiatric disorders." She said recent data suggest that memories can continue to be changed or eliminated long after they have been formed, or consolidated. Based on findings that suggest memories are susceptible to loss after retrieval, a me...

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