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Tag: "insights" at biology news

Alaskan puzzles, monitoring provide insight about North Pacific salmon runs

...Pacific salmon all along the West Coast, providing insights into the fluctuating fortunes of salmon runs and their management. The grant boosts research into climate and other factors affecting salmon in the Northeast Pacific and determining such things as how much habitat -- parts of streams or entire water...

New component of the 'brakes' on nerve regeneration found

...elation to myelin inhibition may provide important insights into designing therapeutic strategies to block myelin inhibition and cell death in the context of CNS injury," they wrote. ### Jong Bae Park, Glenn Yiu, Shinjiro Kaneko, Jing Wang, Jufang Chang, and Zhigang He: "A TNF Receptor Family Member, TROY, ...

Researchers make gains in understanding antibiotic resistance

...ics are no longer effective. According to Steitz, insights about the ribosomal origins of antibiotic resistance are already being applied to the development of new antibiotics. One company leading the way is Rib-X Pharmaceuticals, which was founded by Steitz and colleagues at Yale. "About half of current ant...

Sickle cell and protection against malaria

...n effective vaccine but this work may provide some insights for such research. The authors suggest mechanisms by which HbAS could affect immunity, for example, accelerated acquisition of antibodies to altered host proteins expressed on the malaria-infected red cell surface. ### Citation: Williams TN, Mwangi...

Study reveals new technique for fingerprinting environmental samples

..."EGT fingerprints may be able to offer fundamental insights into the factors impacting on various environments," said DOE JGI Director, Eddy Rubin, who led the research team. "With EGTs we don't actually need a complete genome's worth of data to understand the functions required of the organisms living in a p...

Leprosy microbes lead scientists to immune discovery

... sicker," commented Bloom. "This research gives us insights about how the body develops protective immunity against bugs that invade our cells--or fails to. Now we know the players, and we would love to look at them in other diseases such as tuberculosis in the lungs and juvenile diabetes." Harvard School of...

Used in a new way, RNA interference permanently silences key breast cancer gene

...h. "The technique is also providing some valuable insights into the role of STAT3 and its downstream targets," adds Arlinghaus, who also will discuss the work in a mini symposium at the AACR meeting. RNAi has been employed as a laboratory tool to knock down expression of genes in a variety of cells and orga...

Cerebral navigation: How do nerve fibers know what direction to grow in?

...s from Children's Hospital Boston reveal important insights into how inhibitory cues affect the growth cone, and identify possible targets within axons that could be blocked to overcome this inhibition. Such intervention could possibly enable damaged axons to regenerate (normally impossible in a mature nervou...

Scientists journey to southern Africa to unravel the secret world of elephant communication

...e mammals to communicate through the ground." Her insights generated international media attention after the ...he ground. O'Connell-Rodwell also is applying her insights in animal seismicity to the problem of hearing loss in humans. It turns out that people with hearing...

Biochemists report discovery of structure of major piece of telomerase; implications for cancer

... Cell. "Knowledge of the structure should provide insights into how telomerase works," said Juli Feigon, professor of chemistry and biochemistry at UCLA, who led the research group. "Knowing the structure also will allow the pursuit of rational, structure-based drug design, and is a critical first step. The ...

Defensins Ward Off HIV In Two Ways

...ensin-1 acts on both the virus and the cell offers insights into the function of alpha-defensin-1 in innate immunity against HIV. In addition, this study provides a basis to develop defensin-like drugs for prevention of HIV and for therapeutic use in patients who are already infected. ...

UCSD research reveals mechanism involved with type of fatal epilepsy

...hese models with the hope of gaining the necessary insights to develop potential therapies for Lafora disease. Co-authors are Matthew S. Gentry, Ph.D., and Carolyn A. Worby, Ph.D., both of the UCSD Department of Pharmacy. This research was funded by the National Institutes of Health. ...

Multiple-drug resistant gene expression pattern predicts treatment outcome for pediatric leukemia

...ance to a single drug. "These findings provide new insights into the biological basis of de novo multiple-drug resistance and illuminate potential new targets for overcoming this cause of treatment failure in childhood ALL," explains Dr. Evans. ...

Cellular Defects in Premature Aging Disease are Reversible

...is devastating childhood disease and might provide insights into the normal aging process. HGPS is a rare inherited disease affecting about one in eight million children. While appearing normal at birth, infants with HGPS age rapidly after their first 18 months, and physical symptoms include stunted growth, ...

Supercomputers to focus brains on AIDS dilemma

...chers have been able to discern ever more detailed insights into the microscopic dance of molecular dynamics, where events take place in nanoseconds at length scales far shorter than the wavelength of light. By putting the molecules into motion in their simulations, the researchers discovered that there is a ...

Master gene controls healing of skin in fruit flies and mammals

...n mammalian skin, a finding that could lead to new insights into the healing of wounds and treatment of cancer. The UCSD biologists' study, published April 15 in the journal Science identifies a master gene called grainyhead that activates wound repair genes in the cells surrounding an injury in the cuticle ...

Doing a spin with DNA

...avity of the enzyme. The research has provided new insights into the interactions between DNA and the enzyme, which are of fundamental importance for understanding cell division. DNA consists of two long strands joined together by pairs of bases. Both strands wind around each other in the form of a double he...

Finding hidden invaders in a Hawaiian rain forest

...ies, and the Asner/Vitousek work gives us valuable insights about this problem. On a more practical level we need to know the distribution of invasives. Weeds are often difficult to find in dense, wet forest in Hawaii. This study has helped us with a particularly difficult-to-map species with confusing signat...

Gene keeps neural cells on correct developmental path

...in neurodegenerative diseases. It may also provide insights into other diseases, such as small cell lung cancer, which mistakenly make neuronal proteins, or neurological syndromes, where neuronal proteins produced by cancers may trigger the immune cells to attack the nervous system. The study focuses on a pr...

Science study holds implications for gene therapy and stem cell biology

...e behavior of human stem cells, because so far our insights are limited to mouse models." Dr. Baum said. Scientists, in general, experiment with related gene vectors to treat severe inborn disorders or cancer. There continues to be an increasing interest in gene therapy research with blood stem cells because...

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