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Tag: "insight" at biology news

Quick -- what’s that smell?

...ceive odors. Using an approach that has provided insight into information processing by the visual and auditory systems, the Monell researchers developed a new behavioral paradigm using trained mice to ask whether longer exposure to an odor would result in more accurate identification of that odor. The res...

Non-coding RNAs help silence the mammalian transcription

...man and colleagues (Princeton University) lend new insight into the mechanism of genomic imprinting, demonstrating a necessary role for a non-coding RNA transcript in the silencing of an imprinted gene cluster in mice. Imprinting, or the differential expression of a gene based upon which parent it has been ...

The shape of life: research sheds light on how cells take shape

... "What's exciting is that this finding may provide insight into how the shapes that make up the human body are created." Tang agreed: "Pattern formation is critical to the creation of life. Now we really understand the mechanism behind this type of pattern in microtubules. Force is the key." ...

Ten years later, Dolly is still making headlines

...tor of "Dolly" and world-renowned scientists share insight Making his first U.S. appearance since his book, About Dolly, hit shelves earlier this month, Dr. Ian Wilmut, the lead researcher of a team of scientists who were first to successfully clone an animal, Dolly the sheep, ten years ago, will speak ab...

Scientists identify protein with a crucial role in cell death

...wn for a long time. 'Knock-out' mice To obtain insight into PARL's function, the researchers used mice ?called 'knock-out' mice ?that were no longer able to produce this protein. These mice deteriorated very rapidly ?losing muscular strength after only 4 weeks, which greatly reduced their capacity for br...

Himalayan forests disappearing

... said the researchers, because it yields new basic insight into a central function of behavioral planning in this higher brain region, called the lateral prefrontal cortex (PFC). The researchers, led by Hajime Mushiake of Tohoku University School of Medicine, reported their findings in the May 18, 2006, is...

The brain's executive is an 'event planner'

... said the researchers, because it yields new basic insight into a central function of behavioral planning in this higher brain region, called the lateral prefrontal cortex (PFC). The researchers, led by Hajime Mushiake of Tohoku University School of Medicine, reported their findings in the May 18, 2006, is...

Researchers find cause of frontotemporal dementia

...lin in the formation of FTD provides a totally new insight into how brain cells die off. Van Broeckhoven's team's research indicates that the quantity of progranulin in the brain is important for the brain cells' survival. The hereditary defects that the researchers have found in FTD patients cause only 50% ...

Structure determined for p53 tumor suppressor protein as bound to DNA for anti-cancer activity

...significant insights into p53 function. One new insight from the current study, for example, is that the point of contact between the two core domains of a pair of p53 proteins forming a dimer tracks to a part of the protein often mutated in cancers. This suggests that the interface between the two protei...

Study reveals how cells destroy faulty proteins in cystic fibrosis

...d. "Understanding this pathway gives us greater insight into what's wrong with the protein -- information that will help people design better therapeutics for the disease," Cyr said. ...

Breaks in hibernation help fight bugs

...earchers at Penn State. The finding could offer an insight into the spread and emergence of infectious diseas...ith their hibernating hosts could provide valuable insight into the spread and emergence of zoonotic diseases. ...

Scientists discover a genetic code for organizing DNA within the nucleus

...entire chromosome. The team's findings provided insight into another mystery that has long been puzzling molecular biologists: How do cells direct transcription factors to their intended sites on the DNA, as opposed to the many similar but functionally irrelevant sites along the genomic sequence? The shor...

Septum keeps neurons in synch, can reduce epileptic seizures by 90 percent

... authors wrote. Although this research gives more insight into how epilepsy occurs, a cure is still years away. "But I would say there is hope," Colom said. "We want to offer people with epilepsy new options," he said, but progress will depend upon funding, he added. Next steps The researchers will repe...

Mechanism identified for promising neurological drug

...rofessor of neurology at SFVAMC and UCSF, with the insight that the action of minocycline closely resembles the action of previously known PARP-1 inhibitors. This perception led to "a simple experiment ?putting cells in a dish, doing things to the cells that would activate PARP-1, and seeing what the effect ...

Parkinson's disease mechanism discovered

...illustrate the power of animal models in revealing insight into Parkinson's disease. "These results highlight the value and importance of very simple model organisms in studying these disorders," she said. "For example, yeast is only a single cell, not even a neuron, and yet it can reveal proteins that modif...

Survival of the selfless - scientists find cheats don't always prosper

...oitative cheats is unexpected and gives us greater insight into how cooperation evolves. This is important because we live in a world in which cooperations exists at every level, from genes working together to build functioning individuals to individuals forming societies." The researchers suggest that the ...

Key to early diagnosis of autism may be in the placenta

...he children in the study in greater detail to gain insight into the biological basis of the inclusions in ASD. Volkmar said, "If the work is confirmed by the next series of studies, then the finding of trophoblast inclusions at the time of birth in the absence of any obvious genetic abnormalities would be ...

UF scientists discover evolutionary origin of fins, limbs

...d online today in the journal Nature, also provide insight into the evolutionary history of genes involved in...are involved in human birth defects, which provide insight into the evolutionary history of genes and their functions. "Knowing that many of these genes are ...

Researchers map out networks that determine cell fate

... Understanding of leukemias also could be aided by insight into this regulatory circuitry, Singh said. Many leukemias exhibit mixed-lineage patterns of gene expression, for example of both macrophage and lymphocyte genes. "It may be that these cells are stuck in a progenitor-like state," said Singh. "If ...

UF scientists test improved gene therapy method for hereditary heart conditions

...art problems. "The primates were done to give us insight into how this could be used in children," he said, adding that UF researchers hope to launch a trial in patients with Pompe disease early next year. "Many of the inborn errors have their most feared effects early in life, so we're pushing toward bein...

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