Microfossils unravel climate history of tropical Africa
... a lush rainforest. These findings provide further insight in natural variations in climate and the possible ...f a lush rainforest. These results provide further insight into the natural variation of climate and the possible consequences of a warming earth on precipitat...Linheng Li Lab documents the development of cancer stem cells
...n their molecular signature -- providing important insight into targeting these cells," said Robb Krumlauf, Ph.D., Scientific Director. "This is a fascinating new area of cancer research, and Linheng Li and his colleagues will continue to make important contributions." ...Scientists identify specific enzymes that make meningitis hard to fight
...om the body's immune system. This work provides an insight into the precise roles of two enzymes in mending DNA and gives us a greater understanding than ever before into why these infections are so hard for the body to fight. "We have also discovered that this novel combination of enzymes is present in ...MIT: Pulsing light silences overactive neurons
...eases, as well as normal brain circuitry, offering insight into which brain regions and neurons contribute to specific behaviors or pathological states, Boyden said. The halorhodopsin gene was originally discovered in the 1980s, but Boyden didn't think its full potential had been explored. The protein exp...Does a peptide affect the heart's response to social isolation?
...social isolation. The findings may provide further insight into how these mechanisms affect humans. The study was conducted by Angela J. Grippo, C. Sue Carter and Stephen W. Porges, all with the Department of Psychiatry and Brain-Body Center at University of Illinois at Chicago and is titled Chronic Oxytoc...'Exercise pill' switches on gene that tells cells to burn fat
... in metabolism also has given the researchers more insight into how the PPAR-d switch works, says Dr. Evans. Genetically engineering changes in metabolism in the marathon mice triggers both increased fat burning and increased endurance. Adult normal mice that receive the drug to switch on PPAR-d show increa...Cholera pathogen reveals how bacteria generate energy to live
...nderstanding of this pathogen, while also offering insight into how cells transform energy from the environment into the forms required to sustain life. As a single-cell organism, Vibrio cholerae depends on resources in its immediate environment to sustain itself. Blanca Barquera, assistant professor of bio...Linking DNA and histone methylation
...mprehensive Cancer Center) and colleagues lend new insight into the mechanism of epigenetic silencing of euchromatic genes. Dr. Carey emphasizes that "The study provides a new direction to understand how histone and DNA methylation, two phenomena that play a significant role in stem cell differentiation an...NYU scientists identify how development of different species uses same genes with distinct features
...NYU’s Center for Developmental Genetics, offer new insight into the workings of developmental pathways across species. The study is published in the latest issue of the journal Science. The researchers examined the fruit fly Drosophila and the wasp Nasonia as genetic model systems. Fruit flies?development i...Proteins may predict lung transplant rejection
... developing a preventative treatment and also gain insight into the physiological mechanisms of lung rejection. Lung fluid samples from '93-'96 The study used 411 lavage samples obtained from 137 lung transplant recipients from 1993-1996, Wendt explained. A lavage is a liquid that doctors introduce i...Interaction between lymph and liver cells may affect immune response
...n in chronic hepatitis C. "As well as providing insight into the normal immune system, our observations might have implications for liver conditions associated with altered LSEC morphology and in particular those conditions associated with loss of fenestrations such as cirrhosis and old age," the authors ...Growth factor stimulates rapid extension of key motor neurons in brain
...report's senior author. "In addition to providing insight into the development and circuit formation of this critical population of neurons, these results might lead to the future ability to treat motor neuron disorders and spinal cord injuries." Although their cell bodies are located in the brain, CSMN...Unique gene regulation gives chilly bugs survival advantage at bottom of the world
... larvae during this time may give researchers more insight into the nature and role of heat-shock proteins....Living view in animals shows how cells decide to make proteins
...ch tissue or organ. The findings also may offer insight into a number of diseases, including cancer, in wh...ing of splicing decisions may give us considerable insight into the many human diseases associated with improper regulation of splicing."...Chronic jet-lag conditions hasten death in aged mice
...h nonetheless provides, in rather stark terms, new insight into how the disruption of circadian rhythms can impact well-being and physiology, and how those impacts might change with age. The mouse study is reported by a group led by Gene Block and Alec Davidson of the University of Virginia and appears in th...Stem cells engage in dialogue with the cells that regulate their futures
...nsequences for stem-cell therapies and may provide insight on how cancer might spread throughout the body via populations of cancer stem cells." Ruohola-Baker added that stem cells hold high hope in regenerative medicine: tapping into the ways cells repair the body to create therapies to fix or replace in...Uncovering DNA's 'sweet' secret
... efficiently as DNA. "The structure now provides insight of a chemical nature that (the six-carbon sugar) is just too 'bulky.' It has too many atoms," Egli said. The new insights provided by this structure lie at the heart of the most fundamental of scientific inquiries - the origin of life on Earth. If ...Harvard scientists identify compounds that stimulate stem cell growth in the brain
...of The FASEB Journal. The study also provided so insight into the cellular and molecular mechanisms involved when LTB4 stimulates neuronal stem cells. According to the study, cells generated as the result of LTB4 exposure had high levels of LTB4 receptors, whereas the level of LTB4 receptors was considerab......-200 microns of size. These results provide new insight in the design principles which make healthy bone so fracture resistant. The research may contribute to medical as well as technological developments: "The outcome of this research may contribute to a future development of bio-inspired and new nanocom...Ocean sampling yields environmental sources of coral symbionts
...itical group of algae, researchers have gained new insight into the dwelling places of the symbiotic organisms that reef corals need for survival. The symbiosis between special algal species and reef corals is the foundation of a highly productive and biologically complex ecosystem, but our understanding of...