Ready, set, mutate?and may the best microbe win
...,500 generations, the percentage of mutant strains inside the fermentor ebbed and flowed as the single-celled microbes competed for dominance. Eventually, one strain squeezed out almost all the competition by virtue of its ability to most efficiently metabolize food at high temperature. The metabolic prote...Scientists to employ Arctic ice and polar bears to protect diversity of world's crops
...us that would stimulate the immune system, but the inside genes of a harmless variety of virus that could not cause disease. The St. Jude team was the first to use reverse genetics to make a vaccine against H5N1 that moved out of the laboratory and into clinical trials: http://www.stjude.org/media/0,2561,4...New light microscope sharpens scientists' focus
...cope so powerful that it allows scientists peering inside cells to discern the precise location of nearly ea...earn a lot by studying the arrangement of proteins inside cells at this resolution, it is insufficient to pinpoint the location of individual proteins ?which ...Gold nanoparticles could improve antisense cancer drugs
...lenge has been delivering antisense drugs to cells inside the body while avoiding their break down along the...s the message from ever becoming a protein." Once inside cells, the DNA-modified nanoparticles act as messenger RNA "sponges" that bind to their targets and ...H5N1 vaccine could be basis for life-saving stockpile
...us that would stimulate the immune system, but the inside genes of a harmless variety of virus that could not cause disease. The St. Jude team was the first to use reverse genetics to make a vaccine against H5N1 that moved out of the laboratory and into clinical trials: http://www.stjude.org/media/0,2561,4...Even a little cooling helps after cardiac arrest
...ain how to collect snails, identify the trematodes inside them, and then translate this information into information on resident populations of birds, fishes and benthic invertebrates. "We think counting trematodes is an effective tool for assessing the biodiversity of salt marshes in California," Lafferty...Experimental RNA-based drug kills prostate cancer cells effectively and safely
...fing the entire drug molecule. With the drug now inside the cancer cell, the second module, which contains silencing RNA, launches its effect. The silencing RNA seeks out and binds to the RNA for a specific cancer-causing protein, called PLK1, and tags it for destruction. This eventually leads to the deat...How healthy is that marsh? Biologists count parasites
...ain how to collect snails, identify the trematodes inside them, and then translate this information into information on resident populations of birds, fishes and benthic invertebrates. "We think counting trematodes is an effective tool for assessing the biodiversity of salt marshes in California," Lafferty...HIV infection requires an accomplice: B cells with special protein direct HIV to T cells
...nce anchored on the membrane, it's able to slither inside and take command of the cell. But as the Pitt studies have found, there is an important first step in a new pathway involving B cells that express a protein called DC-SIGN. B cells are key players in an immune response. While these cells themselves...Schepens scientists are first to discover angiogenesis switch inside blood vessel cells
...Medical School, are the first to discover a switch inside blood vessel cells that controls angiogenesis (new...ismantle existing vessels by targeting this switch inside the vessel cells." Angiogenesis is an important natural process that can be both good and bad for ...Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial
...ters (billionths of a meter). Getting the siRNA inside tumor cells is important, Sood said, because the targeted protein, focal adhesion kinase (FAK), is inside the cell, rather than on the cell surface where most proteins targeted by cancer drugs are found. "...Primates take weather into account when searching for fruits
... accelerate maturation of fruits and insect larvae inside them. The researchers were able to show that past weather conditions--as opposed to sensory cues such as the smell of ripe fruit--accounted for the behavioral trend they observed. These findings are consistent with the idea that monkeys make foragin...New study reveals components of cocoa may enhance the appearance of the skin
...oa and how it might actually benefit skin from the inside out. Researchers found that certain components in cocoa may actually help improve the appearance of women's skin ?increasing hydration, decreasing skin roughness and scaling, and helping to support the skin's defense against UV damage. The German sc...'Micro-boxes' of water used to study single molecules
...ate and combine the droplets (dubbed "hydrosomes") inside a tiny chamber on a slide. A green laser is then...such as attaching them to surfaces or placing them inside liposomes (artificial cells). The water droplets can be held far from any surface that might interfe...Rehydrate -- your RNA needs it
... known as ribozymes, accelerate chemical reactions inside cells, just as their better-known protein counterp...The latest work shows that water molecules trapped inside the ribozyme's core are essential components of that network. The network acts like a jostling cro...MIT 'seeing machine' offers hope to blind
...ed the virtual environment - which represented the inside of an MIT building - via a joystick that allowed them to move forward, backward and sideways. All of the participants reported that the machine "may have the potential to assist their mobility in unfamiliar environments," according to the Optometry ...Toxic molecule may cause most common type of muscular dystrophy
...ther scientists can't explain exactly what happens inside the cell to cause someone to get myotonic dystrophy. "The prevailing theory is that the RNA remains in the nucleus, rather than moving out of it, and proteins get stuck to the RNA and aren't able to do their job," Mahadevan said. This toxic RNA in...Bones hold the key to blood renewal
... Bones are really two systems in one. The cavities inside bones are filled with spongy bone marrow, in which stem cells divide and their daughter cells differentiate into all kinds of blood cells, including large numbers of immune cells for the body's defense. The hematopoietic (literally, blood-creating) s...Genes discovered that allow gum disease bacterium to invade arteries
... P. gingivalis that allow it to infect and survive inside artery cells," says Paulo Rodrigues, a researcher .... gingivalis had the ability to invade and survive inside human artery cells. In this study they examined the role four different genes play in this ability.......rotozoan pathogens, especially those that multiply inside of cells, elicit an immune response in the host that would normally cause inflammation, but that worm parasites mount an anti-inflammatory defense that modulates it," said Mansfield, a professor of large animal clinical sciences. "The greater the imm...