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Tag: "inside" at biology news

The power of one: A simpler, cheaper method for cell fusion

..." Lu's device consists of fluid-filled channels inside a tiny microchip. Prior to fusion, cells are engineered to bond to one another by using a minor chemical treatment. Cells are first placed in an aqueous chamber within the chip, where they pair off. In contact with one another but not yet fused, the ...

New drug blocks influenza, including bird flu virus

...y cell surface molecule that the virus uses to get inside cells. To survive and reproduce, viruses must gain access to cells where they make new infectious particles to infect yet more cells in a cascade of infection. The scientific team emphasized that while the new drug shows great promise, much work re...

Brown scientists map structure of DNA-doctoring protein complex

...is made up of bits of mobile DNA, which can travel inside the body and insert genes into the chromosomes of ...their function, you begin to see how the real work inside cells gets done." Sun said solving the structure of the DNA-protein complex called for some creat...

Novel pathway regulates timing of brain cell development

...researchers showed. The half of erbB4 that resides inside the cell--a protein called E4ICD--then joins with other proteins in the cell and travels to the cell nucleus. "Once in the nucleus, E4ICD represses genes that trigger astrocyte production, and thereby inhibits astrocyte formation," explains S. Pablo ...

New technique boosts size of proteins that can be analyzed

...es a far more efficient way to break down proteins inside the mass spectrometer -- sprayed, heated and then bashed with gas molecules -- to obtain their pieces for the mass analysis. They are sprayed in an electric field where they pick up charges and are vaporized as they pass through a heated capillary. T...

American scientist's research of life's first cells

...behaviors. For example, when the genome replicates inside a vesicle, osmotic pressure leads the vesicle to "steal" membrane from other, empty vesicles. This could be an example of Darwinian evolution, according to Chen. "Exploration of these minimal systems promises to lead to more exciting insights into th...

Plants give up answers in the war on bacteria

... like dangerous E. coli, cannot easily gain access inside the plant helps scientists know how to best combat bacteria that cause foodborne illness. It is important to know, he explained, whether foodborne illnesses rest on the surface of an edible plant, or nestle inside, impervious to washing. "We are t...

T for two: Scientists show how immune system chooses best way to fight infection

...nting the mother from rejecting the foetus growing inside her." ...

A new target for painkillers

...mple, feeling pain from a foot rubbing against the inside of a shoe ?and feel an exaggerated response to things that are painful. Common pain medicines like aspirin, ibuprofen and acetaminophen often fail to relieve neuropathic pain. Morphine-like opiods such as oxycodone sometimes are used, but can caus...

'Trojan Horse' agent halts bone metastasis in mice

...y helps us understand more about how VEGF operates inside the body and how it is involved in bone remodeling." Rosenblum said that phase I human clinical trials testing VEGF121/rGel are expected to open shortly at M. D. Anderson. ...

Electric jolt triggers release of biomolecules, nanoparticles

...ompatible implant chip that would release medicine inside a patient on command. Scientists elsewhere are w...fabricated containers that unload their medication inside the body when a lid dissolves. Although it requires further research and development, the Searson te...

Biologists probe the machinery of cellular protein factories

... by ribosomes, tiny protein factories humming away inside the cells of all living things. Harry Noller, the Sinsheimer Professor of Molecular Biology at the University of California, Santa Cruz, has been studying the ribosome for more than 30 years. His main goal is to understand how the ribosome works an...

Chemical tests of cell growth enter third dimension

...y, cells cling to supportive tissues as they grow; inside the FBB, they cling to strands of polyester fibers...d to intensify the signal so that it could be read inside the well, by cultivating the cells in three dimensions." Yang and his team created a device that us...

Brain regions do not communicate efficiently in adults with autism

...uggests inefficient and inconsistent communication inside the brains of people with autism and may explain some of the deficits shown by people who have the disorder. The research has practical applications. Murias believes the abnormal patterns of brain activity are a potential biological marker of a...

Nano-devices hold promise for early-stage cancer detection

...hat will provide early detection of abnormal cells inside the body; an imaging and communication system for non-invasive screening in target organs systems such as the breast, pancreas and gastrointestinal tract and the relaying of information to an external receiver; developing ingestible and insertab...

Newly discovered behavior in cancer cells signals dangerous metastasis

...ing," a key element of the genetic copying program inside cells. Alternative splicing determines how the DNA is chopped into pieces and then reassembled. The order in which DNA is reassembled determines which proteins the gene produces. In cancer cells, the splicing machinery goes awry -- as do myriad func...

Stanford discovery may help predict when toxoplasma can be deadly

...e numerous challenges of infecting and reproducing inside such a wide range of creatures has long intrigued scientists, and now researchers at the Stanford University School of Medicine have identified two of the proteins critical to its ability to thrive. The findings will be published in the Dec. 15 i...

UCSD researchers create roadmap to integrin activation

...ng molecules, transferring information between the inside and outside of a cell at plasma membrane sites. ...ther and blocking the blood vessel. A signal from inside the platelet to the outside tells the GPIIb-IIIa integrin on the cell's surface to get sticky. Di...

Two-faced protein can stop metastasis or promote it, researchers say

...other cadherin proteins on adjacent cells. On the inside of the cell membrane, cadherins bind, chain-like, ..., forming a strong barrier-like layer covering the inside of organs and body cavities and the outside skin of humans. "E-cadherin holds a human's cells and ti...

Innovative movies show real-time immune-cell activity within tumors

...ument called a two-photon microscope, able to peer inside living tissues. The microscope tracked and recorded the movements in three dimensions over time of T cells in a transgenic mouse developed by Weninger and Ulrich von Andrian at Harvard Medical School in which the cells fluoresce green. In addition, f...

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