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Tag: "innate" at biology news

Worms produce surprise insight into human fever

...two “highly conserved? cell-signaling pathways for innate immunity shared by worms and humans. For one, we ...me of these basic pathways that set off the worm’s innate immune defenses have homologs—similar proteins in mammal cells, including ours. These conserved pa...

PNAS study reveals why organs fail following massive trauma

...volution. White blood cells of the more primitive innate system, like neutrophils and macrophages, form the...hemicals are also toxic to nearby human cells, the innate response is normally shut down quickly by the onset of the more time-consuming, precise and thorough...

'Killer' B cells demonstrate evolutionary link between fish and mammal immune systems

...tibodies to fight infection, to the more primitive innate immunity in fish, where they found that B cells take part in phagocytosis (literally: cell eating), the process by which cells of the immune system ingest foreign particles and microbes. The finding, which appears in the online version of Nature Im...

New study finds similarities between monkey business and human business

...at loss-aversion extends beyond humans, and may be innate rather than learned." ...

Fly's courtship sheds light on the formation of innate behaviors

...s and other animals. Yet the manner by which these innate behaviours are hard-wired into our brains remains obscure. In their new work, the researchers set out to address this question using mutations that perturb the stereotypical male courtship behavior of the fruit fly Drosophila melanogaster. The male...

Report focuses on the role good microbes play in future medicine

...essary for the appropriate development of both the innate and acquired immune systems. Once established, probiotic organisms interact with these immune defenses, possibly changing the nature of the immune response to other antigens, including commensal and pathogenic organisms," says Walker. The report is...

Light guides flight of migratory birds

...fusing picture. Migratory birds are born with an innate magnetic compass preference that coincides with their species' migratory direction. Previous research suggested that before the migration period, songbirds are able to recalibrate the magnetic compass when exposed to a "conflict" between magnetic and...

Study details hepatitis C ability to block immune system response

...ctions like hepatitis C often trigger an immediate innate immune response involving release of type 1 interferon (IFN-? and IFN-?). In turn, type 1 interferon stimulates the production of a family of what are known as IFN stimulated genes that have a multitude of inhibitory effects on viral replication in i...

Radiation-killed bacteria vaccine induces broad immune response in mice

...stem (antibodies and T cells), but also the body's innate immune system. However, traditional ways of making... preserve the pathogen's ability to trigger strong innate and adaptive immune responses. "By showing that whole, irradiated bacteria can form the basis of a ...

Researches discover gene critical for protection against septic-shock-induced death

...f2, plays a critical role in regulating the body's innate immune response to sepsis and septic shock, accord...els of effector molecules (cytokines) that mediate innate immune response, the body's first line of defense. "Sepsis syndrome is like a speeding car with a br...

Protein found to control tumor growth in certain breast cancers

...as previously thought to play a role solely in the innate immune system's response to bacterial infection. In the new study, which will be published on-line by the Proceedings of the National Academy of Sciences of the United States of America on January 23, researchers showed for the first time that the pr...

Researchers reveal lung's unique innate immune system

...time, scientists have documented an organ-specific innate immune system. In research published in the April...sive strategies against microbial invasion. "This innate immune response is specific to the lung, and was probably designed to minimize collateral damage to ...

Animal brains 'hard-wired' to recognize predator's foot movements, Queen's study suggests

...re easily from a car than by foot may be due to an innate "life detector" tuned to the visual movements of an approaching predator's feet, says Queen's University psychologist Niko Troje. "We believe this visual filter is used to signal the presence of animals that are propelled by the motion of their fee...

How taste response is hard-wired into the brain

...eem to demand that such behavioral responses be so innate as to be hard-wired into the brain. Indeed, in studies with the easily manipulable fruit fly Drosophila, Kristin Scott and colleagues reported in the January 19, 2006, issue of Neuron experiments demonstrating just such a hard-wired circuitry. Their...

UCSB researchers discover shape matters to macrophages

...arch 28. Phagocytosis, a key part of the body's innate immune system, depends on macrophages ?the cell's clean-up crew. The macrophages find and frequently remove particles from the body. Prior to this discovery, it was believed that the ability of a macrophage to process a particle through phagocytosi...

Born with a love of speech

...re to separate out possible in-utero exposure from innate predisposition. At the core of the studies is a unique set of complex speech analogues designed to be as close to speech as possible, without being words. This provided a stringent test for a newborn's ability to distinguish speech from other sounds...

Lack of a key enzyme dramatically increases resistance to sepsis

...ase-12, which appears to modulate inflammation and innate immunity in humans, increases the body's "vulnerability to bacterial infection and septic shock" while a deficiency confers strong resistance to sepsis. This new discovery suggests that caspase-12 antagonists could be a potentially useful in the trea...

Immune system response to viral DNA is unique

...ator, and senior author of the study, compared the innate immune response to intracellular DNA with other virus recognition pathways. "We found that this novel pathway seems to function differently from all other known nucleic acid sensors," Stetson said. "The unique immune response activated by foreign DN...

'Uniquely human' component of language found in gregarious birds

...han you might think," Margoliash said. "They have innate abilities. They solve interesting problems and learn difficult tasks. Any number of times during the experiments I said 'they can't possibly do that,' and they did." "There has long been a temptation," writes cognitive neuroscientist Gary Marcus o...

Newly identified mechanism helps explain why people of African descent are more vulnerable to TB

...in humans called Toll-like receptors contribute to innate immune responses. The researchers describe a novel...portant to learn how much vitamin D is optimal for innate immunity, and how that can best be achieved through diet or supplementation," said the senior invest...

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