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Tag: "injections" at biology news

Duke to test bird flu vaccine dosing

... response but required high doses and at least two injections to initiate a strong response, Walter said. Trial participants will receive varying strengths of the H5N1 vaccine, either with or without an aluminum hydroxide adjuvant. An adjuvant works by increasing the body's immune response to a vaccine, Walter...

DNA gene vaccine protects against harmful protein of Alzheimer's disease

...that trial. In that earlier study, people received injections of the protein itself and some developed dangerous...ears using a blast of helium. After receiving 11 injections over several months, the mice showed a high level of antibodies to amyloid-beta 42, and a 60 percent...

Human trial proves ricin vaccine safe, induces neutralizing antibodies; further tests planned

...dividuals in each group received a series of three injections of various doses of the vaccine, called RiVax, over the study period. As a recombinant vaccine, RiVax is a form of ricin that consists of a genetically modified subunit of the toxin, rather than an inactivated whole toxin. All five of the individual...

Needle-free immunizations

...ia, Santa Barbara, says the myriad shortcomings of injections have led to active research and development of nee...es, improper and unsafe use of the needles used in injections causes millions of cases of hepatitis B and hepatitis C, and thousands of HIV infections. The World...

Mouse study: New muscle-building agent beats all previous ones

...miting protein myostatin. In mice, just two weekly injections of the new agent triggered a 60 percent increase i...ffects on other proteins, explains Lee. After five injections over four weeks, mighty mice injected with the new agent had muscles 24 percent larger than their co...

Asleep in the deep: Model helps assess ocean-injection strategy for combating greenhouse effect

...ddressed before decisions are made on whether such injections are a viable way to reduce carbon dioxide emission into the atmosphere, Zhang added. Zhang's work was described in a paper in the Oct.1 issue of the journal Environmental Science & Technology. The research was partially supported by the National...

Study shows combination of immune substances to be safe

...ction and then intravenously. That was followed by injections of interferon over the next five days. On average, patients received five such cycles over the course of the study. The drug combination not only proved to be safe ?which was the purpose of the study ?but the researchers found that it stopped disea...

Polymer gel can block toxic leakage problem in gene therapy

...own algae can also block toxic leakages from tumor injections when mixed with the adenoviruses. However, the high viscosity of that jello-like mixture made it hard to inject. "The bottom line is that when people try to do gene therapy on cancer they must inject the genes into the tumor," Yuan said. "One way wo...

Research Permits First-Ever Visualization of Psychological Stress in the Human Brain

...t it’s entirely non-invasive ?without the need for injections or radioactivity. In this elegant technique, water molecules in subjects?own blood are ‘tagged?by the magnet and used as the natural contrast agent to measure cerebral blood-flow.?Researchers at Penn’s Center for Functional Neuroimaging have been at ...

Bone marrow stem cells may heal hearts even years after heart attacks

...heart muscle and improved heart function following injections of stem cells directly into the heart muscle or infusions of stem cells into key heart arteries soon after a heart attack. This study is the first to report the results of stem cell infusions into the arteries of patients many months or years after ...

Scientists use gene transfer technology and common virus to block neuropathic pain

...ed much less pain-related behavior after receiving injections of the HSV-based vector, which contained a gene ca... One week after surgery, some of the rats received injections of the HSV vector with GAD, while control rats did not receive the vector. Rats given the transgene ...

Scientists use gene transfer technology and common virus to block neuropathic pain in animals

...ed much less pain-related behavior after receiving injections of the HSV-based vector, which contained a gene ca... One week after surgery, some of the rats received injections of the HSV vector with GAD, while control rats did not receive the vector. Rats given the transgene ...

Results of world's first gene therapy trial for arthritis show approach safe, feasible

...he gene-modified cells, and two knuckles receiving injections of cells with no added gene. One week later, at the time of the patient's previously scheduled surgery, the four knuckles were removed for study and replaced with artificial joints. In their animal studies that preceded the clinical trial, the resea...

Columbia scientists develop cancer terminator viruses

...umors on just one side of the animal with very few injections of this modified virus not only cured the injected tumors, but also resulted in the destruction of the tumors on the opposite side of the animal. Instead of carrying IFN-�� as the other virus did, this virus carried a gene called mda-7/IL-24, a nove...

Visceral Leishmaniasis: Successful Vaccine Trial In Dogs

...adjuvant. The other six received no treatment. Two injections at an interval of three weeks resulted in infection of all the animals with L. infantum. They were followed up for two years in order to monitor the progress of the disease. The mixture of parasite proteins proved to be especially effective, as 100% ...

Gene therapy to lower blood pressure just enough

...t remains is whether the body will accept repeated injections of the viral vector or whether its immune system eventually react against it, said O'Malley. ...

Compound might defeat African sleeping sickness, clinical trial beginning this month

...e access to clinics or trained staff that can give injections or administer drugs intravenously. "Immtech International, Inc. of Vernon Hills, Ill., a pharmaceutical company and a contributor to this drug development effort, has an exclusive, worldwide license to DB289 and related compounds developed by the UN...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

...eliver protein-based drugs-such as via needle-free injections or through inhalation. But, these delivery methods pose their own significant challenges. Ultimately, Shen and colleagues began to reconsider the possibilities of oral drug administration. Their first breakthrough came when they began to recognize t...

'EuroVacc 02' HIV Vaccine Trial Begins

...hibition of the transporter are reduced. The first injections prime the immune system whereas the second injections further enhance (boost) the immune response. Therefore this combined vaccine strategy is expected to...

Remote control flies? Fly behavior controlled by laser light

... giant fiber system cells and using the tiniest of injections to place the caged ATP inside the flies, the researchers shone a ultraviolet-wavelength laser in brief, millisecond pulses at the flies trapped inside a glass-domed arena. On command, the flies began a series of escape movements--extending their legs...

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