Highly concentrated botulinum preparation for cosmetic injections can result in severe illness
...mination of 4 cases of botulism following cosmetic injections to the face indicates that the adults received a h...e-patients with a link to cosmetic botulinum toxin injections were reported to the Centers for Disease Control and Prevention. Daniel S. Chertow, M.D., M.P.H., ...New biologic treatment for tennis elbow may replace surgery for chronic sufferers
...inflammatory drugs, bracing, physical therapy, and injections of corticosteroids (cortisone shots) are often used but recent studies have called into question their efficacy. Those who suffer longest resort to surgical repair of the tendon when all other therapies have failed. Mishra and Pavelko evaluated 14...Targeted virus compels cancer cells to eat themselves
...ant gliomas in the brain, those treated with three injections of hTERT-Ad on average lived 53 days. Those receiving the control adenoviruses lived on average 29 days. Two of the hTERT-Ad mice survived 60 days and had no detectable brain tumors. Analyses of dead cancer cells showed telltale signs of autophagy:...Gene transfer using mutant form of good cholesterol cuts vascular plaque and inflammation
...rials at the Cleveland Clinic in which intravenous injections were found to shrink plaque in human coronary arteries. The Cedars-Sinai researchers, collaborating with researchers from Sweden, also are developing vaccine against LDL cholesterol (bad cholesterol) that one day may be administered in childhood t...The appearance of your hands can reveal your age, study finds
...ents and chemical peels can reduce age spots. Fat injections can be used to plump up hands and reduce the visibility of veins and laser ablation of unwanted hand veins can reduce veins." ...Dopamine drug leads to new neurons and recovery of function in rat model of Parkinson's
... are approved to treat PD. The rats also received injections of a chemical called bromodeoxyuridine (BrdU), which marks proliferating cells, and infusions of a substance that fluorescently "traces" how neurons connect. The animals were tested before and 3 days after receiving the treatment to see how well the...Smokers invite to test vaccine against nicotine addiction
...a one-year commitment to come to San Francisco for injections and follow-up visits. The study also includes five behavioral counseling sessions. Participants will be paid for each visit and given validated parking at the clinic. ...Successful transplantation from pig embryos to mice
Millions of diabetics face a lifetime of daily injections to replace the insulin their bodies fail to produce, as well as a host of risks that includes blindness, amputation, kidney failure, and heart disease. For many, particularly those afflicted with juvenile diabetes, transplants of the pancreatic tissu...Experimental RNA-based drug kills prostate cancer cells effectively and safely
...ng one injection every two days, for a total of 10 injections over 20 days. By the end of the study, the tumors in the 10 treated mice had shrunk two-fold in volume, while the tumors in the 10 control animals had more than tripled in size. "The animals themselves showed no signs of side effects," Giangrande s...Neurons grown from embryonic stem cells restore function in paralyzed rats
...nt combination of treatments. Some groups received injections of a drug called rolipram under the skin before and after the transplants. Rolipram, a drug approved to treat depression, helps to counteract axon-inhibiting signals from myelin. Some animals also received transplants of neural stem cells that secret...UC Davis researchers move biotechnology closer to replacing electronic pacemakers
...sdifferentiation. Studies done two weeks after the injections showed the new nodes were able to take over pacemaking function from the electronic devices. The results also have implications for future stem cell research. Li and his colleagues are now preparing to do long-term, follow-up experiments. UC Davis ...Mass. General study finds potential ovarian cancer stem cells
...o the formation of new tumors much faster than did injections of regular tumor cells. Although the potential ovarian cancer stem cells were less responsive than regular tumor cells to in vitro treatment with the chemotherapy drug doxorubicin, the stem-like cells remained sensitive to repeated treatment wit...Drug triggers body's mechanism to reverse aging effect on memory process
...red from the animals' bodies. The drug used in the injections has a half-life of only 15 minutes; the increase in LTP was seen in the rats' brains more than 18 hours later. According to the researchers, this study suggests that pharmaceutical products based on ampakines can be developed that do not need to be i...Genetically altered mice no longer like cocaine
...ers ?served as controls and were given only saline injections throughout the experiment. Individual mice were p... box. During the next several days, mice received injections of saline and then various amounts of cocaine on alternating days. Mice injected with saline were co...Newly discovered killer cell fights cancer
...ts were that tumors shrunk in mice, which received injections of IKDCs, but not in those receiving conventional NK cells only. Evidence from the shrunken tumors revealed certain "cell-killing" proteins that could be traced to IKDCs. These results are published separately in Nature Medicine. Housseau's group ...Plant-derived vaccines safeguard against deadly plague
...delivered by typical intramuscular or subcutaneous injections -- the way most vaccines are normally given," said Mason, an associate professor in the School of Life Sciences. "This new system produces really high levels of antigens in relatively short periods of time." The researchers modified tobacco plants t...Curry and cauliflower could halt prostate cancer
...ction of the prostate cancer cells. They found the injections significantly retarded the growth of cancerous tumors. Using PEITC and curcumin in tandem produced even stronger effects. The group went on to evaluate the therapeutic potential of curcumin and PEITC in mice with well-established tumors, and the res...Study by Einstein researchers could lead to a novel strategy for treating obesity
...ected the virus into the hypothalamus of rats. The injections caused a chronic decrease in malonyl CoA levels, which dramatically increased the rats' food intake and led to obesity that was maintained for at least four months. "We showed in this study that disrupting malonyl-CoA levels in this region of the br...NJIT engineer poised to take stem cell research a step forward
...nts with spinal cord injuries could be healed with injections of stem cells. "When you injure your spinal cord," Arinzeh said, "you damage your nerve tissue and the neurons. So I'd like to regenerate that nerve tissue by coaxing stem cells to turn into neurons. My hope is that in five years, say, a person wit......eta cells. "We did this in mice, giving them six injections over the course of several weeks. The injections interrupted the T cell and beta cell interaction, allowing the beta cells in the pancreas to regener...