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Tag: "injections" at biology news

Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage

...Strong pain relief resulted, but in some cases the injections caused nerve damage. "Our publication represents the first proof that gene therapy can work in a way that is clinically applicable," said Stephanos Kyrkanides, D.D.S., Ph.D., associate professor of Dentistry at the University of Rochester Medical ...

Peramivir protects mice from lethal H5N1 infection

...oute of administration of peramivir (intramuscular injections alone versus intramuscular injections followed by oral administration) and frequency of administration on the first day of treatment (once...

Implanting dopamine generators in brain cells obtains improvement in Parkinson's in monkeys

...is was not observed in those individuals receiving injections of saline serum instead of the cellular aggregates. The fact that the injection into the striate area of neurotrophic factors (those that favour cell growth), such as GDNF, also causes a significant increase in dopaminergic neurones in this region...

Researchers design pulsed mircrojet system to deliver protein drugs without pain or bruising

...care providers. Currently, about 12 billion needle injections are performed every year for the delivery of vaccines and protein therapeutics such as insulin, growth hormone and erythropoietin, a red blood cell booster. Needle-free delivery of vaccines has recently been identified as one of the significant emer...

NIAID DNA vaccine for H5N1 avian influenza enters human trial

...he ages of 18 and 60. Fifteen will receive placebo injections and 30 will receive three injections of the investigational vaccine over 2 months and will be followed for 1 year. Volunteers will not be...

Manipulating nature: Scientists query wildlife birth-control method

...t animals are suffering side-effects from multiple injections and adjuvant substances (catalysts that modify the action of other agents) designed to boost the effectiveness of immuno-contraceptives. "The most commonly used adjuvant, Freund's adjuvant, also induces a range of undesirable side-effects and its...

UCSF brain tumor vaccine trial shows promising results

...issue. Altogether, Canagelo has now received seven injections of vaccine. “My most recent MRI showed that there is no tumor,?Canagelo said. “I haven’t had any side effects from the treatment, and I’m getting stronger every day. I would urge patients to seek out second opinions and investigate clinical trials...

Swell gel could bring relief to back pain sufferers

Scientists at The University of Manchester believe injections of tiny sponge-like particles could provide an alternative to major surgery in the treatment of chronic lower back pain. Dr Brian Saunders from The School of Materials and Professor Tony Freemont from The Faculty of Medical and Human Sciences have d...

Nanotechnology shows promise as next wrinkle fighter

...ction ?from microdermabrasians to lasers to Botox injections ? and nanoparticles are poised to join the war by warding off dreaded buckles in human skin. Ilsoon Lee, an assistant professor of chemical engineering, along with Ph.D. student Troy Hendricks, published an online article in the American Chemical S...

Experience affects new neuron survival in adult brain; study sheds light on learning, memory

...ber of neurons at four weeks and four months after injections of the chemical marker. This comparison indicates that only young neurons are affected by the repeated experience; once new neurons survive the early period of development, their long-term survival and activity become stable. This suggests that the ...

Protein therapy may reduce infarct size in heart attack patients

...ients were randomized 2:1 to receive intracoronary injections of the active study drug (KAI-9803) vs. placebo in four dose groups (0.05, 0.5, 1.25 or 5.0 mg of KAI-9803). Researchers performed tests to assess heart function at various time points and assessed safety and cardiac outcomes through six months. Th...

Coated nanoparticles solve sticky drug-delivery problem

...se barriers, doctors often must prescribe pills or injections that send drugs through the entire body, an approach that can lead to unwanted side effects or doses that are too weak to provide effective treatment. __IMAGE_2 "Mucus barriers evolved to serve a helpful purpose: to keep things out," said Jus...

New test helps identify hepatitis C patients at high risk of developing cirrhosis

... patients," said Cheung. Treatment includes weekly injections of alpha interferon along with the drug ribavirin, which can cost more than $30,000 per year and can cause flu-like symptoms, nausea, depression and other side effects. And only half of patients undergoing this therapy will be cured of the infect...

Rescuing injured hearts by enhancing regeneration

...ury, the animals were randomly assigned to receive injections with a p38 MAP kinase inhibitor alone, the angiogenesis stimulator FGF1 alone, both agents together, or saline (placebo) for four weeks. Three months later, rats that had received both FGF1 and the p38 MAP kinase inhibitor had markedly improved heart...

A new target for painkillers

...caused by sciatica, with no adverse effects. Daily injections "produced a sustained analgesic effect," the researchers wrote. RgIA was such a potent pain reliever that "about 10 billionths of an ounce reversed the hypersensitivity to pain," McIntosh says. Vc1.1 had a similar effect ?replicating studies by...

Replacing insulin is top-ranked breakthrough foreseen for health in developing world

Eliminating the need for costly insulin injections for diabetics, regenerating heart muscle after it fails, and improving resistance to disease by engineering immune cells top a list of 10 potential breakthroughs for health in developing countries seen emerging from the new world of regenerative medi...

New engineered drug may offer prolonged arthritis relief

...ent estimates suggest it would require perhaps two injections per week of the unmodified drug. "With this advance, we believe treatments could go from twice a week to perhaps twice a month, and that would be a huge clinical gain," she said. By remaining at the site of disease, the drug also might cause fewe...

Vaccine for brain tumors shows promising results

...use of the size of the tumor, Hekkala will receive injections every other week until mid-February. So far, results are promising with no sign of tumor regrowth, according to the Parsa. "Every day I feel better," Hekkala said on a recent visit to UCSF to receive her injection. "I set small goals for myself an...

Brain protein improves stroke symptoms in rats, even when injected after 3 days

...stroke. The study also shows that regular, delayed injections of G-CSF, starting up to three days after experimental stroke, are effective in restoring motor functions in rats. G-CSF is known to improve recovery after a stroke, and it is currently being tested for use in humans. The BMC Biology study is the f...

Gene therapy for hereditary lung disease advances

...mphysema can be treated through weekly intravenous injections of alpha-1 protein derived from human plasma. The injections must continue throughout a patient's life, according to the American Lung Association. It does not c...

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