To slow AIDS in Russia, treat HIV-positive addicts, Stanford study says
...he spread of HIV in Russia suggests that treating injection drug users with antiretroviral medication will sl...he situation is worse among drug users. "Almost no injection drug users in Russia are getting antiretroviral drug therapy," said Owens. Antiretroviral therapi......ached 500 to 1000 mm3, eight to ten days after the injection of tumour cells with or without the antigen, the r...e tumour stopped growing because of the lymphocyte injection three or four days previously, the defenders patrolled slowly (4 micrometres per minute) and halted ...Triplex assay used to assay duplex genomic DNA
...emistry at this time, but rather to develop a flow injection based instrument which is matched to our chemistry," continued Daksis. Their Genome Flow® instrument, which employs hardware from FIALab Instruments of Bellevue, Washington, has one moving part, the syringe pump. It allows samples to be automatically...Intravenous nanoparticle gene therapy shows activity in stage IV lung cancer
... gene therapy clinical trials also involved direct injection into tumors. "This is the first time anyone has shown that a gene can be injected and then be taken up and expressed in cancer cells at distant sites," said Jack Roth, M.D., professor of the M. D. Anderson Department of Thoracic and Cardiovascular...Erectile dysfunction in diabetes is due to selective defect in the brain
...animals were randomly selected to receive chemical injection of the streptozotocin (STZ) to induce diabetes. Those rats that did not receive STZ (vehicle injected) served as controls. The experiments began on each of the rats four weeks after the injections. Four experiments were conducted. Experiment one ...Chlamydia vaccine a step closer to reality
...eing done here," he said. "Despite this current injection of funds, further work and funding is still needed to take this current research through to a vaccine product." QUT researchers working on the project are part of IHBI's Cells and Tissue Domain and include Professors Peter Timms, Ken Beagley, As...Researchers design pulsed mircrojet system to deliver protein drugs without pain or bruising
...thout the pain or bruising that deeper penetration injection systems cause. The research was published online today in the Proceedings of the National Academy of Sciences. The effort to create needle-free drug delivery systems is driven by a combination of factors, including needle phobia, pain and discomfor...Blood sugar's manufacture limited by building blocks' supply
..., into pyruvate. Consistent with this observation, injection of pyruvate, but not alanine, rescued the mice from their fasting hypoglycemia. The findings point to a novel form of control over glucose levels, the researchers said. Ultimately, this "window into glucose control" might also have implications fo...Researchers wake up viruses inside tumors to image and then destroy cancers
...Tumors glowed in mice given Velcade followed by an injection of FIAU, but not in mice that weren't given Velcad..., all the while cranking out TK," Pomper says. "An injection of FIAU made it easy to image the tumors with virus in them." The method is highly sensitive, he ...Implanting dopamine generators in brain cells obtains improvement in Parkinson's in monkeys
...d of the cellular aggregates. The fact that the injection into the striate area of neurotrophic factors (those that favour cell growth), such as GDNF, also causes a significant increase in dopaminergic neurones in this region of the brain indicates that the beneficial effect produced by the implant of cellu...Risk of lymphoma increases with hepatitis C virus infection
...ocioeconomic status, and particularly a history of injection drug use or blood transfusions received before 1990, when screening for hepatitis C virus was started. ...Newborn neurons like to hang with the 'in' crowd
...e observed that between three and four weeks after injection of the virus newborn neurons sent out dendritic filopodia—tiny feelers that probe the environment. "When we analyzed them in three dimensions, the tip of the filopodia was preferentially associated with synapses already connected to other neurons," e...pHLIP, a novel technology to locate and treat tumors
...cally accumulate in tumors. Within 20 hours after injection of labeled pHLIP, the molecules had passed through the bloodstream and accumulated in mouse breast tumors grown to different “stages?on the leg of a mouse. The researchers demonstrated that by attaching fluorescent probes to a pHLIP peptide, tumor...Peramivir protects mice from lethal H5N1 infection
...or eight days. In contrast, a single intramuscular injection resulted in a 40 percent survival rate, while two ...d the rate to 60 percent. The single intramuscular injection did not completely inhibit H5N1 virus replication in the lungs and spleen, but did decrease the spre...Scripps research team sheds light on long-sought cold sensation gene
...s shown by a reduction in the response to formalin injection when compared to the amount of time control mice spent flicking and licking their paws when placed on a room temperature plate. In contrast, TRPM8-deficient mice did not receive any acute pain relief from the cold plate suggesting that cold activatio...Better insight into brain anatomical structures
...al examination. Magnetic resonance images after injection of the manganese oxide nanoparticles gave a view into different areas of the mouse brains—in excellent resolution. "We have developed the first truly biocompatible MRI contrast agent for anatomical brain imaging," Lee and Hyeon point out. "With this ...Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage
.... In the current study, researchers found that one injection of a newly designed gene therapy relieved 100 perc...involved a technique that delivers gene therapy by injection at the joint, other promising approaches may involve interrupting crosstalk in the brain instead. Ba...Researchers examine carbon capture and storage to combat global warming
...t won't leak, and do a good job of engineering the injection systems and paying attention to where the carbon dioxide is actually going,'' Orr said. While a thorough technical understanding of the risks will reveal best practices, the scientists also stressed the need for good management to see that proper ...