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Tag: "injection" at biology news

Novel therapy combinations gain ground in treating hepatitis

...enias. CIFN patients experienced a higher rate of injection site reactions and a slightly higher drop-out rate of 18 percent, compared to only 12 percent of the pegIFN group. 28 Days of the Hepatitis C Protease Inhibitor VX-950, In Combination with Peg-Interferon-Alfa-2a and Ribavirin, is Well-Tolerated a...

New GI technologies improve internal organ visualization

...lve. The repeat puncture of the cardiac walls and injection of contrast to help visualize the tissues showed n...scle after a heart attack and may benefit from the injection of therapies directly into the muscle without another operation." Endoscopic Ultrasound (EUS)-Guid...

Injection may prevent infertility in men receiving cancer chemotherapy

...d that his work showed for the first time that the injection of a drug that enhances the immune system could pr...r weight loss compared with the control group. An injection of AS101 a day before that of Taxol prevented the Taxol-induced weight loss. "Tissue analysis of ...

Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

...it to a tumor without being injected directly, and injection methods used in the lab are not practical for clinical use. The research team took siRNA that targets a protein that helps ovarian cancer cells survive and spread and rolled it into a liposome -- a lipid ball so small that its dimensions are measu...

Experimental RNA-based drug kills prostate cancer cells effectively and safely

...into the mice's prostate tumors, administering one injection every two days, for a total of 10 injections over 20 days. By the end of the study, the tumors in the 10 treated mice had shrunk two-fold in volume, while the tumors in the 10 control animals had more than tripled in size. "The animals themselves s...

With few factors, adult cells take on character of embryonic stem cells

...to all an animal's tissues and organs. Following injection into blastocysts, iPS cells also contributed to mouse embryonic development. "The finding is an important step in controlling pluripotency, which may eventually allow the creation of pluripotent cells directly from somatic cells of patients," Yaman...

Sperm created in the laboratory from embryonic stem cells produce viable progeny

...the capacity develop into sperm. Intra-cytoplasmic injection of the ES-derived sperm into mouse eggs resulted in successful fertilization and the resulting early stage embryos were successfully transplanted into mice. Six of the seven mice born developed into adult mice. The results of this study establish t...

Researcher studies, treats military with 'silent disease'

...tandard treatment--24 to 48 weeks of a once-a-week injection with interferon and several pills of ribavirin each day--are what Sjogren speculated would cause a decrease in quality of the volunteers' lives. "The medications are tough to take," she said. On initial questionnaires, study volunteers reported that...

'Smart' genetic therapy helps the body to heal itself

...oon start a clinical trial, based on intramuscular injection of a single dose of an anti-sense drug that induces the skipping of exon 51 from the DMD gene. Six Dutch DMD patients aged between 8 and 16 years with genetic mutations that are correctable by skipping that particular exon will take part. This huma...

Stomach receptor for H. pylori discovered

...hology and behavior of the epithelial cells due to injection of bacterial proteins into the cells. This interaction can lead to peptic ulcer disease, gastric adenocarcinoma, and non-Hodgkins lymphoma of the stomach. "Ulcers are a breach in the gastric or duodenal mucosa and gastric adenocarcinoma is one ...

MRSA vaccine shows promise in mouse study

...xample, but 60 percent of vaccinated mice survived injection with that strain. "Further testing," said first author of the study Yukiko K. Stranger-Jones, a graduate student in the Schneewind Lab, "may yield a molecular appreciation of immunity against S. aureus and permit rational development of a vaccine."...

Fat stem cells being studied as option for breast reconstruction

...imal models, the researchers hope to prove that an injection of fat-derived stem cells that are seeded onto microscopic scaffold structures will enable the production of a durable, replacement soft tissue. The team, led by J. Peter Rubin, M.D., assistant professor of plastic and reconstructive surgery at the U...

High dopamine transporter levels not correlated with ADHD

...mine transporter levels, each subject was given an injection of a radiotracer (a radioactively labeled chemical) designed to bind to dopamine transporters while lying in a positron emission tomography (PET) scanner. The PET camera picks up the radioactive signal from the tracer to precisely measure the level o...

Gene therapy study takes aim at prostate cancer

...design of the study is simple, said Kadmon. "One injection into the prostate that should take no more than 10 minutes, although patients will be monitored in a special unit of the hospital for 23 hours to make sure there are no side effects. After that, they come to the unit for a check-up once a week." Af...

New biologic treatment for tennis elbow may replace surgery for chronic sufferers

... treatment. Fifteen patients received a one-time injection of platelet-rich plasma (PRP) into their affected ...a control (non-PRP) group and received a 2 to 3 mL injection of a local anesthetic (bupivacaine with epinephrine) into the affected elbow. The mean duration of ...

Insulin receptor stops progression of Alzheimer's disease

...ing findings was that peripheral (intraperitoneal) injection of the PPAR agonists either partially or completely rescued the brains from neurodegeneration," the authors write. Alzheimer's appears to be caused by parallel abnormalities ?impaired insulin signaling and oxidative stress, which is regulated by the...

Changing length of days reverses how estrogen affects aggressiveness in mice

..., a type of estrogen. The findings showed that the injection increased aggression in mice in winter-like short days almost immediately. It had no noticeable immediate behavioral effect on the mice living in longer day lengths. Overall, then, these studies showed estrogen increases aggression in short-day mi...

Highly concentrated botulinum preparation for cosmetic injections can result in severe illness

... sufficient to kill approximately 14,286 adults by injection if disseminated evenly. "Botulism is a potentially fatal disease, which invariably presents with acute bilateral cranial neuropathies, regardless of exposure mechanism. Early recognition of botulism, treatment in an intensive care setting, provisio...

Brain protein improves stroke symptoms in rats, even when injected after 3 days

... the open access journal BMC Biology shows that an injection of Granulocyte-Colony Stimulating Factor (G-CSF), ...fferent types of stroke to assess the effect of an injection of G-CSF on recovery. The first model was used to assess the impact of G-CSF on the size of the ...

New HIV statistics indicate increasing toll of AIDS on African American community

...he African-American community. Reduce role of injection drug use in sustaining the AIDS epidemic. ?Among b...ted to the sharing of contaminated needles through injection drug use. Reducing the role of injection drug use in the spread of HIV will require an increased in...

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