New male contraceptive clears hurdle
...y returns if the RISUG is flushed out with another injection that dissolves the gel. Elaine Lissner, director of the nonprofit Male Contraception Information Project in San Francisco, says she is not surprised that American men are watching the RISUG trial with keen interest. She emphasizes that the method ha...Canine cancer vaccine program shows early promise
...ells and immune stimulant, when administered as an injection into the patient's skin, has been shown to stimulate the immune system to specifically fight against the melanoma cells. Dogs that first had surgery for their melanoma and then received vaccine lived cancer-free for approximately twice as long as d...Master genetic switch found for chronic pain
...uncomfortable prick of a filament (mechanical); an injection of an inflammation-inducing chemical (inflammatory); or nerve damage (neuropathic). They quantified the animals' response by measuring how long the animals lifted or licked their affected paw in response to the treatments. Ma and his colleagues foun...Researchers reverse juvenile diabetes in animal model
...ritical part of how diabetes occurs. Subcutaneous injection of dendritic cells into the abdominal/pelvic area near the pancreas and lymph nodes, blocks the T cells as they travel to the pancreas to destroy beta cells. "We did this in mice, giving them six injections over the course of several weeks. The inj...'Bad' enzymes may wear white hats after stroke
...itor at different times after the stroke. When the injection was given immediately following the stroke, rats showed smaller areas of brain damage. Injections given at three days had no effect, but those given at seven days or 14 days led to more extensive brain damage, compared with rats that did not receive ...Scientists design potent anthrax toxin inhibitor
...tor in rats. When given in relatively small doses, injection of the inhibitor at the same time as anthrax toxin prevented five out of nine rats from becoming ill. Slightly higher doses of the inhibitor prevented eight out of nine rats from being sickened by anthrax toxin. Nine additional rats were injected wit...Unique equine cataract surgery offered on routine basis
...lens using an ultrasound probe and administered an injection of intravitreal steroids to control postoperative inflammation of the eye. Professor Knottenbelt said: "This new surgery shows how effectively the latest human cataract surgical techniques can translate successfully to bear on an equine problem. ...Potential heart benefit found in stem cells
...were thicker than in the animals not receiving the injection (5.9 vs. 3.6 millimeters), and the same difference...myopathy were treated with a combined percutaneous injection (both intramyocardial and intracoronary, either the heart muscle or the heart's artery) of bone marr...Scientists force viruses to evolve as better delivery vehicles for gene therapy
...han the wild AAV, and two evolved strains survived injection into mice with nearly 1,000 times the level of antibodies required to neutralize the wild virus. By sequencing the survivor strains, the researchers discovered that the capsid proteins of the survivors differed from those of the original strain by o...Stem cell transplants improve recovery in animal models for stroke, cerebral palsy
...h control animals and those that received a single injection of stem cells were evaluated for a period of up to 2 months. Improvements in stem cell treated animals included enhanced performance across the range of tests, which examined strength, balance, agility and fine motor skills, and also included greate......e their prey," Dr St Pierre said. "Firstly, venom injection causes massive blood clots instantaneously followed by paralysis as a result of neurotoxins which eventually immobilise and kill the victim." Dr St Pierre said mammals and snakes naturally produced a small amount of Factor X in their livers. "Snake...New 'self-exploding' microcapsules could take sting out of drug delivery
...e vaccines are administered. Instead of an initial injection followed by a series of boosters, for instance, certain vaccines could be given in a single shot with the "booster" microcapsules timed to rupture at appropriate intervals. ...Computer scientist sorts out confusable drug names
... as a documented case in which a patient needed an injection of Narcan but received Norcuron and went into cardiac arrest. A few years ago, the FDA turned to Project Performance Corporation (PPC), a U.S. software company, to ensure they don't approve the names of new drugs that may easily be confused with an...Trial success for diabetic nerve therapy
... University of Manchester team has discovered that injection of a novel therapeutic that works by stimulating a...ts," he said. "Our tests have shown that a single injection of a DNA-binding protein protected nerve function, stimulated nerve growth and prevented tissue dama...UF scientists test improved gene therapy method for hereditary heart conditions
...w way of delivering corrective genes with a single injection into a vein holds promise for long-lasting treatme...ene expression in the heart but it was with direct injection into the heart muscle and it was inefficient," said UF pediatric cardiologist Barry J. Byrne, M.D., ...With few factors, adult cells take on character of embryonic stem cells
...to all an animal's tissues and organs. Following injection into blastocysts, iPS cells also contributed to mouse embryonic development. "The finding is an important step in controlling pluripotency, which may eventually allow the creation of pluripotent cells directly from somatic cells of patients," Yaman...UC Davis researchers move biotechnology closer to replacing electronic pacemakers
...s' hearts had generated bioartificial nodes at the injection sites. Li explained that, through gene expression, normal muscle cells of the heart were converted into pacemaker cells by a process called transdifferentiation. Studies done two weeks after the injections showed the new nodes were able to take over ...High-dose flu vaccines appear to safely boost immunity in elderly
... to receive one of the three vaccines or a placebo injection and then were monitored daily for one week afterwa...discomfort, redness or swelling at the site of the injection was more common among those who received the 60 ìg dose than among those who received the 15 ìg dose...UF scientists restore sight to chickens with blinding disease
...quite a long time to build the vector, develop the injection procedure and figure out how to hatch the eggs. By doing the injection early during development, we actually treat the cells before they become photoreceptors." Infants ...Septum keeps neurons in synch, can reduce epileptic seizures by 90 percent
...thesia, by stimulating the septum directly with an injection of carbachol, or by using the sensory stimulation method of pinching the tail.) The amplitude and frequency of the theta rhythm of the epileptic rats was significantly altered compared to the control group. In effect, the theta rhythm became faster...