Studies clarify risk factors for mother-to-child transmission of hepatitis C virus
...ivery, infant prematurity, and maternal history of injection drug use were not associated with HCV transmission. The overall rate of transmission of the virus from infected mother to child was 6.2 percent in the European study and 3.6 percent in the U.S. study. "Our results strongly suggest that women shoul...OHSU researchers discover potential mechanism to repair brain damage linked to Multiple Sclerosis
... Back confirmed in another animal model of MS that injection of the HA into damaged myelin prevented myelin from reforming where it had already been destroyed. Conversely, they showed that reducing HA levels or making the HA inactive allows myelin to once again form. "It is our hope that we can interfere with...Molecular Partners Required For Appropriate Neuronal Gene Repression
... Back confirmed in another animal model of MS that injection of the HA into damaged myelin prevented myelin from reforming where it had already been destroyed. Conversely, they showed that reducing HA levels or making the HA inactive allows myelin to once again form. "It is our hope that we can interfere with...Updated data on novel HPV vaccine confirms efficacy in large population
... reported in the trial was local discomfort at the injection site. The study is part of an ongoing phase III program involving more than 25,000 people in 33 countries. For the FUTURE II study, a prospective, randomized, double-blind, placebo-controlled study, women aged 16 to 26 years were randomized to rec...Bone marrow stem cells may heal hearts even years after heart attacks
...nt. This therapy is safe, similar to an 'own blood injection or transfusion,' and has no side effects. It needs only bone marrow puncture and cell aspiration with subsequent stem cell preparation," he said. Although this study did not look at how stem cells may heal heart attack damage, other studies have sho...Climate change will affect carbon sequestration in oceans, model shows
...ocean will change with climate change. The direct injection of carbon dioxide deep into the ocean has been sug...ness of oceanic carbon sequestration by the direct injection of carbon dioxide at different locations and depths. They found that climate change has a big impac...Gene therapy reverses genetic mutation responsible for heart failure in muscular dystrophy
...s, Dr. Xiao's team found that direct intramuscular injection of AAV was effective in transferring a gene into muscle cells in a fairly wide area around the injection site. However, for gene therapy treatments to be successful, particularly for muscular dystrophies w...How 'Dirt' Could Educate The Immune System And Help Treat Asthma
...ocean will change with climate change. The direct injection of carbon dioxide deep into the ocean has been sug...ness of oceanic carbon sequestration by the direct injection of carbon dioxide at different locations and depths. They found that climate change has a big impac...Grabbing addiction by the tail
...rast, addicted animals who received an intravenous injection of the artificial peptide displayed no sensitized behavior. "The effect was immediate and very noticeable," said Wang. There are several types of glutamate receptors involved in memory and learning, but because the artificial peptide specifically t...University of Delaware researchers develop cancer 'nanobomb'
...the nanotubes can provide for the highly selective injection of drugs into individual cells. As they undertook various experiments, however, the team made a startling discovery. "When you put the atoms in different shapes and forms, they take on different properties at the nanoscale," Panchapakesan said. "W...Magnetic probe successfully tracks implanted cells in cancer patients
...ity and that ultrasound failed to accurately guide injection of the cells into lymph nodes in half of the patie...agnetically labeled stem cells with MRI-compatible injection systems to allow MRI guidance of injection in large animals. The current clinical trial builds on B...Polymer gel can block toxic leakage problem in gene therapy
...o tumors themselves. However, direct intratumoral injection can cause the gene-bearing viruses to escape their...iny tumor blood vessels created by damage from the injection needle. Yuan said such viral escapes are inevitable since the needle's diameter is 30 times larger ...Blocking the nerve receptor EP1 in mouse models reduces brain damage caused by stroke
...rain) of mice. A group of control mice received an injection of the solvent used to carry the drugs. The investigators then injected each mouse with NMDA, a drug that stimulates the NMDA receptor. Excessive stimulation of these receptors by NMDA, such as during stroke, leads to nerve cell damage. In mice tha...Synthetic Protein Eases Arthritis Symptoms in Mice
...scientists used a variety of techniques (including injection of TNF-alpha) to induce arthritis symptoms in mice. Researchers also injected some of the animals with lab-made PLAD (P60 PLAD). “We found that P60 PLAD protein powerfully inhibited the symptoms of TNF-alpha-induced arthritis,?says Dr. Lenardo. P60 P...Study shows combination of immune substances to be safe
...treatment, patients were given IL-12, initially by injection and then intravenously. That was followed by injections of interferon over the next five days. On average, patients received five such cycles over the course of the study. The drug combination not only proved to be safe ?which was the purpose of th...Asleep in the deep: Model helps assess ocean-injection strategy for combating greenhouse effect
...nimals to death." The challenge in designing CO2 injection strategies is figuring out how to keep droplets of...ofessor of geological sciences. However, at a high injection rate, seawater full of CO2 droplets would have an average density smaller than that of surrounding s...Mouse study: New muscle-building agent beats all previous ones
...e muscle group analyzed, and mice treated with one injection a week for two, three or four weeks continued to gain muscle mass. But although the new agent seems quite promising, its advantage in potency also requires extra caution. "We don't know what else the new agent is affecting or whether those effects ...Stem cell mobilization therapy appears to be ineffective in repairing damage caused by heart attack
...oms. Patients were randomly assigned to receive by injection either a daily dose of 10 µg/kg of G-CSF or placebo (an inactive substance) for 5 days. The patients were treated between February 2004 and February 2005. Treatment with G-CSF produced a significant mobilization of bone marrow stem cells. The resear...DNA gene vaccine protects against harmful protein of Alzheimer's disease
...er's Disease Center at UT Southwestern. The gene injection avoids a serious side-effect that caused the cance...ly seen in animals with these mutations. The gene injection showed superior results compared to a previous human study in which amyloid-beta 42 protein itself w...HIV/AIDS rates in Tijuana, Mexico increasing at alarming rate
... that high-risk groups ?men who have sex with men, injection drugs users, sex workers and pregnant women ?are o...IV/AIDS in the border region, needle sharing among injection drug users leads to increased HIV infection, and Tijuana is on a major drug-trafficking route. The ...