Fat screen delivers plant-derived chemical with antidiabetic effects
...ectly, the chemical blocks a pathway that normally inhibits fat cells' production. "Harmine inhibits an inhibitor for a net positive effect on fat" that ultimately appears to restore insulin response w...Scientists discover rare 'gene-for-gene' interaction that helps bacteria kill their host
... Photorhabdus bacteria produce an antibiotic which inhibits the work of an enzyme that insects' immune systems use to defend themselves from attack. Although such so-called gene-for-gene interactions are thought to be common in diseases, very few examples of a single gene in a pathogen targeting a single g...Hearts of male and female rainbow trout are different
... found in the fish heart -- citrate (an acid which inhibits the glycolytic metabolic pathway) and pyruvate dehydrogenase (PDH), the enzyme allowing carbohydrates to be oxidized -- differ between the sexes. The researchers hypothesized that male hearts would have higher citrate levels and females would benefi...Researchers shed light on mechanism of action used by anti-cancer drug
...earchers identified a mechanism by which sorafenib inhibits protein translation, and which may be involved in reducing expression of pro-survival factors, such as Mcl-1, and other proteins. The findings were published online in the journal Molecular and Cellular Biology on June 4. According to Grant, soraf...