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Tag: "inhibits" at biology news

Friendly bacteria in alcoholic milkshake could fight food allergies

...Food and Agriculture has shown that the milk drink inhibits the allergen specific antibody Immunoglobulin E (IgE). IgE is involved in immune responses to inactivate organisms that might cause disease. However, in the presence of allergens it can also activate cells responsible for the release of histamine, a ...

Plant-derived molecules, genetic manipulation point to future chemoprevention methods

... of circulating insulin-like growth factor (IGF)-1 inhibits azoxymethane-induced colon tumorigenesis in mice ...aximal, final growth of a young adult animal--also inhibits programmed cell death and stimulates colon epithelial cells, the scientists tested IGF-deficient mic...

Study IDs protein that inhibits HIV from growing in cell cultures

...wa have identified a protein segment that strongly inhibits HIV from growing in cell models. The team found t..."Identifying a specific protein made by GBV-C that inhibits HIV growth in cell culture strengthens the argument that GBV-C is responsible for the prolonged surv...

Novel pathway regulates timing of brain cell development

...nes that trigger astrocyte production, and thereby inhibits astrocyte formation," explains S. Pablo Sardi, PhD, a postdoctoral fellow at Children's and the study's first author. Previous studies have found presenilin activity to be altered in Alzheimer's disease, and that erbB4 is abundant around the plaq...

Gene therapy inhibits epilepsy in animals

...ulates neurons to fire, and the GABA system, which inhibits that brain activity. GABA's inhibitory role is considered particularly important in the dentate gyrus because the dentate gyrus acts as a gateway for brain activity into the hippocampus, an area that is critical to generating seizures in temporal l...

Two nerve cells in direct contact

...e stops from the other half of the brain and which inhibits the H2 cell on the same side with chemical synapses. Both connections were in principle suitable for achieving the effect described; however the question remained: which of the two is the crucial one? The Max Planck scientists therefore blocked the...

Brown team finds crucial protein role in deadly prion spread

...gh drug intervention. If a drug could be made that inhibits this fragmentation process, it could substantially slow the spread of prions, which cause mad cow disease and scrapie in animals and, in rare cases, Creutzfeldt-Jacob disease and kuru in humans. Because similar protein replication occurs in Alzhei...

Multiple malaria infection inhibits spread of parasite

...he gametocyte, the infectious stage. This immunity inhibits the spread of the parasite. Dutch researcher Mike ...a few infections, people can develop immunity that inhibits transmission. Malaria is not caused by a mosquito but by a parasite in the mosquito. The malaria p...

Motor protein plays key role in connecting neurons

... can be cut down to a small molecule that actually inhibits axon growth function," Dr. Xiong says. She susp...tly without its motor domain, it becomes negative, inhibits DCC getting to the proper place and so axonal growth," Dr. Xiong says. ...

Inhibiting blood to save the brain

...cine have identified a fibrin-derived peptide that inhibits this specific inflammation process in mouse models of MS, reducing MS symptoms. "Current strategies to develop therapies to fight MS primarily target T cells," said Katerina Akassoglou, Ph.D., assistant professor in UCSD's Department of Pharmacolog...

Largest genomic search finds genes that may contribute to autism

... Autism is actually a spectrum of disorders that inhibits a person's ability to communicate and develop social relationships. It is often accompanied by extreme behavior challenges. Autism Spectrum Disorders are diagnosed in one of 166 children in the United States and affect four times as many boys as gir...

Lead with a poisonous electron shield

...ortion at the active center could explain why lead inhibits this enzyme. The different behavior of lead in these two enzymes demonstrates that it can enter into complexes in which the metal–ligand bonds can either point in all directions, or into only one hemisphere, while the other hemisphere is filled by...

Gallium: A new antibacterial agent?

...disrupt biological systems by substituting for Fe, inhibits the in vitro growth of Pseudomonas aeruginonsa; even multidrug resistant strains of P. aeruginonsa isolated from individuals with cystic fibrosis. Ga also prevented P. aeruginonsa forming biofilms, the multi-cellular bacterial communities responsible...

How genetic malfunction causes a form of retardation

...ulatory pathway that causes genesis of neurons and inhibits the pathway that generates glial cells. And in experiments with both cell cultures and mouse embryos, they found that the same kind of mutation in SHP-2 that can be found in NS patients disrupts the neuron-glial balance by further promoting the forma...

Carnegie Mellon University research shows how sensory-deprived brain compensates

...t of whiskers on one side of the body dramatically inhibits the ability of a single whisker to remodel the brain," said Barth. "This finding suggests that we could boost the brain's plasticity if we 'turn off' sensory input from the opposite side of the body." Hypothetically, in a clinical setting, doc...

Researchers urge monitoring of bone health during chemotherapy

... a bisphosphonate, an anti-osteoporosis agent that inhibits osteoclasts, were resistant to the effects of G-CSF on bone tumor growth. Weilbaecher is currently investigating bisphosphonates as a means to prevent tumor metastasis to bone in breast cancer patients. "We used G-CSF as a tool to understand the i...

Autism gene identified by researchers at Yale working with a global research consortium

...sease. Autism is a complex brain disorder that inhibits a person’s ability to communicate and develop social relationships, and is often accompanied by extreme behavioral challenges. Autism Spectrum Disorders are diagnosed in one in 150 children in the United States, affecting four times as many boys as g...

Bacterial walls come tumbling down

...enzyme works and how a very good animal antibiotic inhibits the enzyme." Although moenomycin is poorly absorbed by the human body, the new understanding of exactly how it interferes with bacterial enzyme function should help scientists design modified versions that are more suitable for use in people. Unde...

Discovery could lead to better control of hemorrhagic fever viruses

...ill test these antibodies, hoping to find one that inhibits virus entry without compromising TfR1's essential function in cellular iron uptake. "If some of these antibodies work, they could be used clinically fairly soon," Choe says. Coincidentally, Stephen Harrison, PhD, a structural biologist and H...

Baumann Lab defines proteins that distinguish chromosome ends from DNA double-strand breaks

...door to elucidate the mechanism by which RAP1/TRF2 inhibits double-strand break repair at chromosome ends." "These findings are important for establishing a better understanding of tumor development," said Robb Krumlauf, Ph.D., Scientific Director. "Genomic instability and gross chromosomal rearrangements ...

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