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Tag: "inhibits" at biology news
Gene therapy to lower blood pressure just enough
...kidney eliminates sodium or salt from the body and inhibits other systems, such as the sympathetic nervous system, believed linked to development of high blood pressure. "This makes ANP an attractive agent for use in treating blood pressure," said O'Malley. "However, its use is limited by the fact that it h...Engineered skin offers clues to melanoma development
...ent kinase 4 (CDK4),which promotes cell growth and inhibits Rb function, induced invasive melanoma in human tissue. Similarly, inhibition of p53, when combined with Ras and hTERT, resulted in invasive melanoma. The scientists also investigated the role of elevated telomerase activity. In combination with oth......ent kinase 4 (CDK4),which promotes cell growth and inhibits Rb function, induced invasive melanoma in human tissue. Similarly, inhibition of p53, when combined with Ras and hTERT, resulted in invasive melanoma. The scientists also investigated the role of elevated telomerase activity. In combination with oth...Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance
...ent kinase 4 (CDK4),which promotes cell growth and inhibits Rb function, induced invasive melanoma in human tissue. Similarly, inhibition of p53, when combined with Ras and hTERT, resulted in invasive melanoma. The scientists also investigated the role of elevated telomerase activity. In combination with oth...Targeting a key enzyme with gene therapy reversed course of Alzheimer's disease in mouse models
...rug companies have been trying to find a drug that inhibits BACE1 and thus prevent beta amyloid from building up in brains of people with Alzheimer's disease. But so far, the goal has remained elusive. Instead of looking for chemical compounds to inhibit BACE1, Oded Singer, collaborating with the laboratorie...Researchers find molecule that inhibits regrowth of spinal nerve cells
...o block nerve growth, a component called ephrin-B3 inhibits such activity as well or better than that of other known blocking agents combined, UT Southwestern researchers report in an upcoming issue of the Proceedings of the National Academy of Sciences. "I believe that to the extent that overcoming myelin-b...Suppressing growth hormone in early adulthood may prevent cancer
...the normal animals. Suppression of IGF-1 activity inhibits the proliferation of numerous cell types and cancers. "IGF-1 levels in the blood can be reduced by low-calorie diets, which could be a mechanism for the diet-cancer relationship," said Sonntag, whose work explores the neurobiology of aging. Previous...Single gene is genetic switch for fly sexual behavior
... "not only promotes male-female courtship, it also inhibits male-male courtship," the researchers say. Dickson and Demir refer to fruitless as a behavioral "switch gene" that is both necessary and sufficient to produce a particular behavior. Switch genes that trigger the development of a particular anatomica...UNC scientists discover new role for protein as fundamental inhibitor of cell movement
...al of Cell Biology. The study indicates that CIB1 inhibits cell migration by binding to and activating a prot... cells. When CIB1 activates PAK1, this kinase then inhibits cell migration by adding a phosphate group to a host of other proteins in the cell. Thus, the study...Drug resistant avian influenza viruses more common in Southeast Asia than North America
...l step in the replication of the virus. Amantadine inhibits the function of the M2 protein and thus stops viral replication. "By analyzing the sequence of the transmembrane part of the M2 gene we were able to determine how frequently amantadine resistance occurs in avian influenza A subtypes isolated in var...Hepatitis C complicated by morphine withdrawal
...lture that morphine enhances virus replication and inhibits IFN-alpha (a natural anti-viral factor produced by immune, as well as host cells, and the only one approved in recombinant form for treating HCV infection). To further these results, his lab has used a cell model system to determine the consequences...Anti-cancer Compound In Beer Gaining Interest
...s that helps the body detoxify carcinogens. And it inhibits tumor growth at an early stage. In recent years, it has also been shown that some prenylflavonoids found in hops are potent phytoestrogens, and could ultimately have value in prevention or treatment of post-menopausal "hot flashes" and osteoporosis ...New clues to the dark side of a key anti-tumor guardian
...at is, a disfunctional version of the protein that inhibits the activity of normal p53--extended flies' life span and increased their ability to withstand gene-damaging stress. The authors found that this disruption of p53 did not further increase the lifespan of flies on a calorie-restricted diet, suggesting...Machinery of the 'marijuana munchies'
...tion" (DSI). What's more, they found that leptin inhibits DSI. However, they found that leptin did not interfere with the CB1 receptors themselves. Rather, leptin "short-circuits" the endocannabinoid effects by inhibiting pore-like channels in the neurons that regulate the flow of calcium into the neurons. ...Federal grant funds research on novel HIV therapy
... binds to the substance P receptor in immune cells inhibits HIV from entering its hiding place within immune cells. That compound, from a class of agents called neurokinin-1 receptor antagonists, may represent a new type of anti-HIV therapy, due to its ability to block HIV replication. The new program projec...Researchers discover new form of cancer gene regulation
... GLI1 is made, it binds to the Quaking protein and inhibits the translation event. This means that all of the controls that the cell has on the gene for GLI1 can be present and active and the GLI1 is still not produced. Significantly, the study demonstrated that this regulation is conserved from human to the...Hot-spring bacteria flip a metabolic switch
...s, since the oxygen produced during photosynthesis inhibits the nitrogenase complex--the enzyme factory that fixes N2. Other organisms have found creative solutions to this dilemma. For example, plants rely on symbiotic N2-fixing bacteria that live in their roots, far away from the photosynthetic leaves. A di...New drug could reduce tissue damage after heart attack
...ge London) scientists has designed a new drug that inhibits the adverse effects of C reactive protein (CRP), a...ound, bis(phosphocholine)-hexane, is bound by CRP, inhibits all CRP functions in the test tube, and blocks the tissue damaging effect of CRP in an experimental ...Boosting newborns' immune responses
...hite cells' production of the cytokine IL-6, which inhibits parts of the immune response, is greater than that in adults. A third study, to be published in the Journal of Immunology, finds that newborns' cord blood also has high levels of adenosine, providing an explanation for newborns' altered immune resp...New compound stops brain cell degeneration in Alzheimer's disease
...ce, the compound, called MW01-5-188WH, selectively inhibits production of pro-inflammatory proteins called cytokines by glia, important cells of the central nervous system that normally help the body mount a response, but are overactivated in certain neurodegenerative diseases, such as Alzheimer's disease, Pa...Other Tagsdip 2Other Contentsyouryouryouryouryouryouryouryouryourodorodorodorodorbreastfeedingbreastfeedingbreastfeedingbreastsbreastsmothersmothersmothersmothersmothersmotherssoundssoundssoundssoundssoundsdifficultiesdifficultiesdifficultiesdifficultiesdifficultiesdifficultiesdifficultiesdifficultiesbreechbreech
(Date:12/1/2009)...nited States, the other from Canada, put the satel..., on remote Ellesmere Island, only 600 miles from ...at these "North Pole wolves" do in the long, dark ... world., "We first encountered 9-year-old Brutus...eological Survey (USGS) wolf researcher who has be...
(Date:12/1/2009)...e mystery, and it is a question which has continue...ring plants evolve and how did they come to domina...Letters reveals the evolutionary trigger which le...itive advantage over rival species, leading to the...y Dr Tim Brodribb and Dr Taylor Field of the Univ...
(Date:11/30/2009)...ert at the holiday table are even less of a help t...g to a new research report recently appearing onli...), a diet that is high in fat and in sugar actuall...es to store too much fat. This means these foods h...lt task of converting high-fat and high-sugar food...
Breaking Biology News(10 mins):North Pole wolf emails locations to researchers 2North Pole wolf emails locations to researchers 3How did flowering plants evolve to dominate Earth? 2Happy holidays from the groaning board; Western diets turn on fat genes 2Ozone nitrogen change the way rising CO2 affects Earths water 9194 1Ozone nitrogen change the way rising CO2 affects Earths water 9194 2Ozone nitrogen change the way rising CO2 affects Earths water 9194 3Got Moving Stories 3F Calling All Reporters Writers Producers and Editors 51229 1Got Moving Stories 3F Calling All Reporters Writers Producers and Editors 51229 2Got Moving Stories 3F Calling All Reporters Writers Producers and Editors 51229 3Chief Medical Officer Joins Aon Consultings Health 26 Benefits Practice 51226 1Chief Medical Officer Joins Aon Consultings Health 26 Benefits Practice 51226 2Chief Medical Officer Joins Aon Consultings Health 26 Benefits Practice 51226 3(Date:12/1/2009)...ery preterm births more likely, British study find...- Pregnant women who are poor are more likely to d...n, even though both groups typically receive equal...ity of Leicester research team said their findings... between economic status and preterm birth. , F...
(Date:12/1/2009)... CAEAR Foundation Changes Name to HealthHIV , ...he CAEAR Foundation, one of the largest national H...to HealthHIV and launching a new website. The anno...t of a campaign to promote the organization’..., , , , ,“HealthHIV clearly, quickly and ea...
(Date:12/1/2009)...Y, Dec. 1 The government of Mexico...center for biomedical and nanomedical research, ca... research and development will be integrated with ...top Spanish speaking university in the world. The... in 2010, has been designed by the internationally...
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(Date:12/1/2009)...ss affirming, isolating behaviors jump from frien...ay News) -- A new study suggests that lonely peopl...o feel lonely, too. , "Loneliness can spread fr...es of separation," said James H. Fowler, co-author...he Journal of Personality and Social Psychology ,...
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