Chlamydia parasite lives off our fat
...a pathogenesis. When the researchers used drugs to inhibit lipid droplet formation in the host, they sharply impaired bacterial growth. That finding immediately presents a new target for anti-Chlamydia drugs but it also suggests an entirely novel pathogenic mechanism. "We propose that Chlamydia use lipid dr...Nano springs eternal; Protozoan 'engine' posts nano records
...so had specialized biochemical methods to slow and inhibit the contraction, to freeze-frame it, and to discern details of the calcium fuel system. Earlier research had identified a cellular protein, spasmin, as the possible calcium-responsive component of the stalk. "The Vorticella spasmins are now known t...Are U.S. Flu Death Figures More PR Than Science?
...so had specialized biochemical methods to slow and inhibit the contraction, to freeze-frame it, and to discern details of the calcium fuel system. Earlier research had identified a cellular protein, spasmin, as the possible calcium-responsive component of the stalk. "The Vorticella spasmins are now known t...Similar Stem Cells In Insect And Human Gut
...so had specialized biochemical methods to slow and inhibit the contraction, to freeze-frame it, and to discern details of the calcium fuel system. Earlier research had identified a cellular protein, spasmin, as the possible calcium-responsive component of the stalk. "The Vorticella spasmins are now known t...Technique offers new view of dynamic biological landscape
...MAPs can answer. They want to know whether if they inhibit a protein -- in this case with a drug instead of k..., clinicians want to know whether -- if drugs that inhibit each of two proteins slow down a cancer or virus -- the two proteins interact epistatically, such th...DNA gene vaccine protects against harmful protein of Alzheimer's disease
...ntibody is therapeutically effective as a means to inhibit the formation of amyloid-beta storage in the brain, and it is," said Dr. Roger Rosenberg, the study's senior author and director of the Alzheimer's Disease Center at UT Southwestern. The gene injection avoids a serious side-effect that caused the c...Embryos tell story of Earth's earliest animals
...sses that occur very soon after cells die and also inhibit voracious bacteria. Hydrogen sulfide is known to have been present in the environment half a billion years ago, at the time of the animal kingdom's origin, and when the embryos died, because sulfur-containing pyrite ("fool's gold") is found in the ...A biosensor layered like lasagna
... detector, but after that, the more enzyme layers" inhibit diffusion of the glucose. Now that the glucose enzyme biosensor has passed the test, Lin said, it should be possible to build a similar sensor using other enzymes that react specifically with other biological chemicals, environmental agents or even...Plants give pests sock in the gut
...lack Mexican sweet corn cells that express Mir1-CP inhibit caterpillar growth by 70 percent, Luthe says. Mir1-CP is harmful to caterpillars mainly because of its damaging effect on their peritrophic matrix. This is a membrane that lines the gut of most insects and aids digestion. It also protects the insect...Satellites show Amazon parks, indigenous reserves stop forest clearing
...f 38). But parks' and indigenous lands' ability to inhibit deforestation appear similar. Indigenous lands o... that virtually all indigenous lands substantially inhibit deforestation up to 400 years after contact with the national society. There was no correlation betw...Researchers reverse juvenile diabetes in animal model
...a laboratory. This treatment strategy was found to inhibit the interaction and destructive effect of T cells on the insulin-producing beta cells of the pancreas, a process that is known to be a critical part of how diabetes occurs. Subcutaneous injection of dendritic cells into the abdominal/pelvic area nea...'Bad' enzymes may wear white hats after stroke
...me current stroke treatment research seeks ways to inhibit MMPs to minimize their danger ?but this new study ...urrent efforts to design MMP-targeted drugs aim to inhibit the enzymes completely after a stroke, the researchers caution that, based on their findings, it may...Boosting newborns' immune responses
...e stimulated. When Levy's team used antagonists to inhibit adenosine's activity, newborns' white blood cells produced normal, adult levels of TNF-alpha in response to bacterial and viral triggers. "In the future, we could try to block adenosine in newborn animals to see if this helps protect against infecti...Flesh-eating bacteria escape body's safety net
...with standard antibiotics, a treatment strategy to inhibit the Strep DNA-degrading enzyme could disarm the pathogen, making it susceptible to clearance by our normal immune defenses," he said. ...'Executive' monkeys influenced by other executives, not subordinates
...pening around them. And people didn't seem able to inhibit or control their reaction." However, he said, there were hints that gaze-following didn't have all the features of a purely reflexive action, but these were only hints. Such hints -- as well as previous studies in the Platt laboratory -- led Shepher...Scientists a step closer to protecting world's most important crop
...hope this discovery will help develop chemicals to inhibit the disease. It's possible that more specific, environmentally friendly, compounds to combat rice diseases could result from this research." Last year scientists from The University of Exeter helped to complete the sequence of the rice blast fungus ...Sweet 'water taste' paradoxically predicts sweet taste inhibitors
...g sodium saccharin and acesulfame-K, paradoxically inhibit sweet taste at high concentrations. The researcher...t discovered that high concentrations of saccharin inhibit the sweetness of any other sweetener tasted at the same time. Testing a variety of compounds, the ...Cholesterol gets 'thumbs up' for role in digit development
...ells, scientists speculated that cholesterol might inhibit the movement of Sonic hedgehog through the developing tissue. This unique modification might explain why concentrations of the protein were high at the site of its production and then tapered off with increasing distance from the synthesis site. Bu...Darkness unveils vital metabolic fuel switch between sugar and fat
...ntly took five to seven hours of light exposure to inhibit the gene's expression in the liver. Taken together, these time delays pointed to the gene's expression being mediated by something in the blood. Another lab test showed elevated levels of 5'-AMP in the blood of mice exposed to constant darkness com...'Nano-keys' bind cell receptors and trigger allergic reactions
...d to receptors) that trigger a desired response or inhibit an allergic reaction and preventing the release of histamines and other inflammatory mediators. In her presentation, "Design and Fabrication of Stimuli to Reveal Spatial Regulation of Cellular Signaling," she explained, "We want to understand how th...