Antivirals effectively curb influenza virus
...s a preventive measure to reduce the spread of the influenza virus, according to an analysis of household-based... with oseltamivir may reduce the infectiousness of influenza patients, although further studies are needed to provide a definitive conclusion. "Preventing the s...Study uncovers a lethal secret of 1918 influenza virus
In a study of non-human primates infected with the influenza virus that killed 50 million people in 1918, an in... how the 1918 virus - modern history's most savage influenza strain - unleashes an immune response that destroys the lungs in a matter of days, leading to death....Pacific Rim researchers to collaborate on distributed bioinformatics analysis of avian flu
...ical structures of different subtypes of the avian influenza virus, at the same time as we study their variatio...s intend to: Characterize the function of the influenza viruses using a structure-based approach; Develop simulations of the molecular dynamics involving...2,000 influenza virus genomes now completed and publicly accessible
...etic blueprints of more than 2,000 human and avian influenza viruses taken from samples around the world have b...is information will help scientists understand how influenza viruses evolve and spread," says NIH Director Elias A. Zerhouni, M.D., "and it will aid in the devel...Bird flu -- Call for antiviral drugs to be shared
...r travel to model the global spread of an emerging influenza pandemic and its containment. They conclude that much will depend on the 'reproductive number' (a measure of how many people an infectious individual infects on average) of the new virus that emerges. If this number is low, it will take many months b...A first glimpse of the influenza replication machine
In 1918, 50 million people died during a worldwide influenza pandemic caused by mutation of a bird-specific strain of the influenza virus. Recently H5N1, another highly infectious avian strain has caused outbreaks of bird flu around...Evolution of influenza A virus
... understanding of the evolutionary dynamics of the influenza virus determines scientists?ability to survey and ...olutionary properties of the H3N2 subtype of human influenza A virus. The authors, in the first population-based study of its kind, collected a sample group of ...'Protecting virus' offers instant flu protection and converts flu infections into their own vaccines
...d could offer protection against the full range of influenza A infections, including H5N1 and any new pandemic ...letely prevents flu symptoms developing by slowing influenza infection rates to such an extent that the harmful infection becomes a vaccine against that very for...New drug blocks influenza, including bird flu virus
...vel compound that confers broad protection against influenza viruses, including deadly avian influenza. The ne...ll protein molecule -- that effectively blocks the influenza virus from attaching to and entering the cells of its host, thwarting its ability to replicate and i...Air travel and flu: Post-9/11 restrictions delayed start of season
...l. In both the northern and southern hemispheres, influenza epidemics occur annually during the winter flu season. Given the concerns about global epidemics of serious strains of flu, such as occurred in 1918, as well as the more recent, localized outbreaks of 'bird flu', it is important to know more about h...Scientists find mutations that let bird flu adapt to humans
By comparing influenza viruses found in birds with those of the avian vir...es the genetic changes required for the H5N1 avian influenza virus to adapt to easily recognize the receptors that are the gateway to human cells. "We identif...U of S Vaccine and Infectious Disease Organization team discovers key step in flu virus replication
...ization (VIDO) has uncovered a key step in how the influenza virus causes infection. Yan Zhou and her team hav...discovered how a crucial pathway that supports the influenza A virus's ability to reproduce itself is activated, a finding that could pave the way for new drugs ...Twenty Years of Malaria Research: Outcomes and Perspectives
...ived funding to track the development of the avian influenza virus. ...Flu shot effective against drifted influenza, nasal spray vaccine less so
During a year in which the circulating strains of influenza showed genetic differences from the strains in vac...s flu shot was found to be effective in preventing influenza in healthy adults. The live attenuated-virus nasal spray vaccine also prevented illnesses but was le...First-time analysis reveals millions of Europeans left at risk from influenza
...f all high risk populations are receiving seasonal influenza vaccine in Europe, resulting in avoidable morbidit... health officials to visualise the need for better influenza control and implement the World Health Organization's (WHO) recommendations for vaccination coverage...Experimental vaccine protects mice against deadly 1918 flu virus
...vaccine that protects mice against the killer 1918 influenza virus. They also have created a technique for iden...standing and preventing the recurrence of the H1N1 influenza virus that caused the 1918 pandemic and to protecting against virulent flu strains in the future, in...Bird flu vaccine additive may stretch supply
... achieved an effective immune response to an avian influenza vaccine with doses as low as one-quarter of the no... research, the investigators used inactivated H9N2 influenza vaccines--not the H5N1 virus currently feared as a potential pandemic strain. However, the study doe...Molecular 'on/off switch' controls immune defenses against viruses
...those employed by other viruses such as West Nile, influenza and the common cold." Dr. Gale's research centers on studying the mechanisms viruses use to evade immune defenses. Of particular interest is the hepatitis C virus, a blood-borne infection transmitted by intravenous drug use, blood transfusions and...H9N2 avian flu vaccine paired with adjuvant provokes strong human immune response at low doses
... an experimental vaccine against a strain of avian influenza (H9N2) provoked a strong antibody response in huma...onstrating the potential value of adjuvanted avian influenza vaccines," says NIAID Director Anthony S. Fauci, M.D. An adjuvant is a substance that is added to a ......king with a version of the seasonal H3N2 strain of influenza A virus, has been able to distinguish five different kinds of influenza virus particles in the same isolate (sample) and map the distribution of molecules in each of them. ...