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Tag: "inflammatory" at biology news

Brain inflammation may be friend, not foe, for Alzheimer's patients

...rsity of Rochester Medical Center shows that a key inflammatory regulator, a known villain when it comes to parsin... “This work provides evidence that blocking all inflammatory responses in Alzheimer’s disease is not an ideal therapy,” added Shaftel. “This might hinder process...

Blood test may help signal tumor's remission, return in throat cancer patients

...rowth factors play an important role in the body’s inflammatory response and in the growth of cells and new blood vessels. Because the researchers used a bioassay technology that can simultaneously analyze the concentrations of each protein, only a small amount of blood was required for the test. The majority...

Snoring in children might be an allergic type disease

...also found strong associations between allergic or inflammatory diseases and snoring. “Snoring can be an early manifestation of more serious sleep-disordered breathing, so it’s not necessarily a harmless condition,” Dr Marshall added. “In adults habitual snoring is seen as being caused by anatomical problems ...

In mice, drug protects against diabetes and atherosclerosis

... acts as a signal in cells, setting off a chain of inflammatory and metabolic responses to consumption of fatty fo...ind with fatty acids -- the function that leads to inflammatory and metabolic havoc when a high-fat or high-cholesterol diet is consumed. The drug appears to have n...

Breakthrough developments in rheumatoid arthritis reported

...at makes these people susceptible to the disabling inflammatory condition. Dr. Gregersen has finally closed the ... or genetic variants, that are associated with the inflammatory condition and can be used to understand the triggers of the disease. This will provide key insights ...

Researchers develop buckyballs to fight allergy

...ssues except blood. When mast cells are activated, inflammatory substances such as histamine, heparin and a number of cytokines are rapidly released into the tissues and blood, promoting an allergic response. The researchers found that the unique structure of the buckyball enables it to bind to free radicals d...

Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage

...would search for new drugs that interfere with key inflammatory receptors on sensory nerve cells within the CNS. ...A little further out, the new idea that peripheral inflammatory diseases like arthritis can lead to brain inflammation may provide an entirely new way to treat infl...

Detecting cold, feeling pain: Study reveals why menthol feels fresh

...tudying acute and chronic pain, as can result from inflammatory or nerve injury, the researchers say, and a potent...hresholds change in the setting of injury, such as inflammatory and nerve injury, and how these changes may contribute to chronic pain," says senior author David Ju...

Keeping the immune system from starting a 'food fight'

..."floodgate" that serves to protect against such an inflammatory immune response. Their findings appear in the May ...point STAMP2 as a critical factor to prevent overt inflammatory responses during everyday nutrient fluctuations or conditions of nutrient excess. In fat cells, a la...

How to steer a moving cell

...tanding of cell migration in cancer metastasis and inflammatory disease. The study will be published the week of May 7-11 in the journal Proceedings of the National Academy of Sciences (PNAS). Extra-cellular messengers called chemokines are families of small proteins secreted by cells that regulate the cells?...

Gut research yields new anti-cancer approach

...nds known to affect PPARgamma could play a role in inflammatory bowel diseases, a team at the University of Roches...lls and share some of their qualities (e.g. normal inflammatory signals). Unlike normal gut cells, however, cancer cells do not die when removed from the gut wall. ...

Red flag for repetitive stress injuries identified for first time in humans

...ts revealed significant levels of several types of inflammatory mediators ?biomarkers ?which signaled an underlying problem," said Barr. "Also, the more severe the injury, the more biomarkers there were." Future research by the team will look deeper into the potential of biomarkers as indicators of injury and ...

Aspirin discovery may improve cancer treatments

...s, including aspirin, are used to treat a range of inflammatory conditions and can be used to prevent diseases such as cancer, but the way aspirin works is not yet fully understood. In a paper published in the prestigious Journal of Biological Chemistry in April, Professor Bryan Williams, Director of the Monash...

Better assessment of transfusions could save blood

...t is commonly referred to as the anemia of chronic inflammatory disease,?says Howard L. Corwin, M.D., author of the report. The expected benefit of RBC transfusions is an increased oxygen level, which prevents cellular injury. However, studies have not consistently demonstrated that the increased hemoglobin l...

Link found between immune system and high plasma lipid levels

...patic T cells in lipid metabolism." "Those with inflammatory problems such as lupus, rheumatoid arthritis and inflammatory bowel syndrome have a higher incidence of cardiovascular disease, often associated with elevated lip...

Microbes start immune response by sneaking inside cells

... drugs that could more precisely target the body’s inflammatory response in rheumatoid arthritis and some other au...opyrin is implicated in the development of several inflammatory syndromes characterized by recurrent fever, skin rash and arthritis. Cryopyrin triggers a key en...

Indicators for risk of heart disease are higher in passive smokers

... investigated elevated C-reactive protein, another inflammatory marker, and white blood cell count in participants with elevated cotinine levels. They found no significant association. The effect levels seen for fibrinogen and homocysteine were about twice as high when measuring cotinine levels compared to pre...

Blame the brain for high blood pressure

...dea that high blood pressure ?hypertension ? is an inflammatory vascular disease of the brain. One in three people in the UK are likely to develop hypertension, and with 600 million people affected world wide, it is of pandemic proportions. The alarming statistic that nearly 60 per cent of patients remain hype...

Scientists find new genes for Crohn's disease

...urther research to understand how the debilitating inflammatory process is initiated and maintained in many cases ...iscover susceptibility genes for Crohn's and other inflammatory bowel diseases (IBDs). More importantly, those genes are leading us to the biological pathways that ...

New molecular pathway could reveal how cells stick together

...t of disease states, most notably cancer and other inflammatory conditions," Page-McCaw said. Yet the normal function of these proteins is not well understood. The job of MMPs is to cleave other proteins that reside in the space in between cells. Page-McCaw has previously identified a specific protein, called ...

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