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Tag: "inflammation" at biology news

Study illuminates how the plague bacteria causes disease

...berculosis, which are food-borne agents that cause inflammation of the stomach and intestines. All Yersinia bacteria have a virulence plasmid, which is necessary to cause disease. Plasmids are extra DNA molecules frequently found in bacteria containing genes that can be passed from one bacterial strain to another...

Researchers identify new weapon to fight deadly bacterial sepsis

...rreaction by the immune system causing destructive inflammation throughout the body, often leading to heart and other organ failure and death. Even the best hospital intensive care units may be helpless to save patients stricken by severe sepsis. According to a 2003 study by Emory University and the Centers for D...

Researchers create mouse lacking key inflammation gene

...accharide [LPS]-Induced TNF-Alpha Factor) controls inflammation through a completely different pathway than the be...w opportunities for assessing the role of LITAF in inflammation in hopes of designing anti-LITAF drugs for major inflammatory diseases," says Dr. Salomon Amar of Bo...

Hopkins scientists link immune response to 'ghost' parasites and severely congested sinuses

... 250 times more active in people with severe sinus inflammation that persists even after surgery when compared to ...imated 32 million Americans suffer from persistent inflammation of the tissue that lines the nasal and sinus cavities, according to the United States Centers for Di...

Environmental toxins may cause body's defenses to worsen lung disease

...c pulmonary diseases cause irreversible damage and inflammation in the lungs that lead to scarring and narrowing of the airways. The most common of these diseases are obstructive pulmonary disease, chronic bronchitis and emphysema. When a large amount of tissue is destroyed, Borchers says, it can cause irreparabl...

Researchers seek to design first treatment for neuroAIDS

...brain to fight infection. The same reactions cause inflammation (swelling) that presses on brain tissue, reducing ...hut down affected immune cells before they trigger inflammation and prevent cell suicide. The new grant is a partnership between the University of Rochester Medica...

Harvard scientists identify compounds that stimulate stem cell growth in the brain

...two compounds--LTB4 and LXA4. Both play a role in inflammation and are regulators of proliferation of several cell types. When stem cells isolated from the brains of mouse embryos were exposed to LTB4 they proliferated and differentiated, giving rise to additional stem cells and to differentiated neurons with l...

New way of tracking muscle damage from radiation

... following radiation therapy, which is evidence of inflammation that could be treated." The researchers believe that the early changes they see in muscle, such as swelling and leakage, might help them predict how much damage will occur in the muscles during the course of many months. By better understanding wh...

Lungs try to repair damaged elastic fibers

...re to toxins such as cigarette smoke, resulting in inflammation to the small airways and destruction of elastic fibers within alveoli. The patients suffered from emphysema. The team used hyperpolarized magnetic resonance imaging (MRI) to characterize the regions of the lung showing moderate emphysema and regio...

New study aims to stop sepsis in its tracks

... infection goes into overdrive, causing widespread inflammation and dramatic changes in body temperature, blood pressure, breathing, and heart rate. It can lead to the malfunction or failure of several major organs. "The goal of this project is to speed recovery, increase survival rates, and improve the long-te...

Backache beaten by good vibrations?

...reated by physiotherapists. "The pain caused by inflammation of lumbar nerve roots could potentially be reduced with the application of TU, a form of electrotherapy commonly used by physiotherapists to accelerate the resolution of the inflammatory process in a multitude of soft-tissue injuries. The study aims ...

Cellulose nanocrystal research could lead to new vaccines, computer inks

... can combat the effects of some diseases involving inflammation of blood vessels, including diabetes, rheumatoid arthritis, and certain cancers. Ink jet printing was another research project for Roman. She experimented with using ink jet printers to deposit the crystals because the printers?main focus is preci...

Blocking immune cell action increases Alzheimer's-associated protein deposits

... help direct them from the bloodstream to sites of inflammation within the brain. Since CCR2 is known to bind chemokines, proteins that attract immune cells and are elevated in brains affected by Alzheimer's, the receptor could be important for the movement of microglia to the site of amyloid-beta deposits. To t...

FDA causes unnecessary scare about common painkillers

... (NSAIDs) that are often used to treat the pain or inflammation from arthritis. The most commonly used NSAIDs are ibuprofen (Advil®), naproxen (Aleve®), and diclofenac (Voltaren®). There are more than a dozen others, including drugs such as celecoxib (Celebrex®) that are in a special class known as selective C...

Inhibiting blood to save the brain

...it leaks from the blood into the brain, triggering inflammation that leads to MS-related nerve damage. Researchers...fibrin-derived peptide that inhibits this specific inflammation process in mouse models of MS, reducing MS symptoms. "Current strategies to develop therapies to f...

Antibody signal may redirect inflammation to fuel cancer

...vidence mounts that the body's normally protective inflammation response can drive some precancerous tissues to be...Science (AAAS) in a session titled "healthy aging: inflammation and chronic diseases." "Immunologists have known for decades that B cells of the so-called adapt...

Inflammation may play role in metastasis of prostate cancer

...o (UCSD) School of Medicine strongly suggests that inflammation associated with the progression of tumors actually...tial tumor. "Our findings suggest that promoting inflammation of the cancerous tissue, for instance, by performing prostate biopsies, may, ironically, hasten prog...

Penn study on lung-infecting bacterial enzyme suggests new approach to cystic fibrosis treatment

...s of the lipid breakdown are also known to trigger inflammation and cell death. Together, these facts compellingly suggest that SMase plays a critical role in the heretofore mysterious pathogenesis of lung injury in CF patients. They also present a new paradigm for treating CF. Specific inhibitors against the...

New research shows that flu is a trigger of heart attacks

...rchers believe that flu causes an acute and severe inflammation in the body, which, in some patients, can destabilise atherosclerotic plaques [2] in coronary arteries and cause heart attacks. Prof Madjid said: "Most people develop atherosclerotic lesions in their coronary arteries in early childhood and these ...

Twin studies reveal genetic components leading to cardiac and kidney disease

...tion. Its presence indicates a heightened state of inflammation in the body and can indicate cardiovascular risk. CRP is associated with increased blood pressure, body mass index, and insulin resistance, among other factors. In twin subjects with elevated CRP, multiple, common genetic variants were found al...

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