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Tag: "inflammation" at biology news

UQ scientists break new ground in fight against infection & chronic disease

...ategies to combat both acute infection and chronic inflammation and to explore new avenues for treatment of cancer. "Basic research findings such as this underpin all medical research but there is still a long way to go (upwards of 10 years) until any new drugs begin to emerge on the market." ...

Emerging staph strains found to be increasingly deadly and deceptive

...isters on the faces of children, or cellulitis, an inflammation of skin or muscle tissue, can easily be treated and usually resolve in a matter of days. But S. aureus disease also can be much more severe and difficult to treat, affecting vital organs and leading to toxins poisoning the blood and infection overwhe...

New factor implicated in allergy and asthma attacks

...r effects, these tiny particles can trigger severe inflammation of the respiratory passages, producing uncontrolla...actor is necessary to cause the severe respiratory inflammation involved in an allergy or asthma attack. This factor is the damage caused by chemically hyperactive ...

Study reveals genomics of inflammation from severe injury

...n (sepsis) and multiple organ failure. How and why inflammation turns from healing to harming is still mysterious,...This work represents a major step in understanding inflammation in severely injured or burned patients. We hope this knowledge eventually will help physicians bette...

Study Unlocks Insects?Secret for Love in the Dark

...n (sepsis) and multiple organ failure. How and why inflammation turns from healing to harming is still mysterious,...This work represents a major step in understanding inflammation in severely injured or burned patients. We hope this knowledge eventually will help physicians bette...

Dangerous tricksters: Some bacterie use immune cells to reproduce

...ells and activating them. Ultimately the result is inflammation and tissue damage. 'It is quite possible that rhodococci do not really mind this,' Professor Haas says, 'since they can then grab a passing macrophage and colonise fresh material.' The next aim of the Bonn researchers is to investigate which bacteri...

Scientists pinpoint inflammation gene

...an already heightened understanding of the role of inflammation in so many human disorders. "Practically every common disease involves an inflammation component," said John Blangero, Ph.D., a scientist at the Southwest Foundation for Biomedical Resear...

Stroke treatment a step closer after trial

...ge. "The protein targets the molecule that causes inflammation and dramatically reduces the inflammatory markers," said Professor Rothwell, MRC Research Professor and the University's Vice-President for Research. "In the laboratory we were able to reduce damage to the cells by as much as half; if we could cut c...

Blocking the nerve receptor EP1 in mouse models reduces brain damage caused by stroke

... E2 (PGE2), a hormonelike substance long linked to inflammation and other effects. The Hopkins study results suggest that PGE2 causes brain damage following stroke by binding to the EP1 receptor on nerve cells. Therefore, blocking PGE2 activity directly rather than inhibiting COX-2 could reduce brain damage in in...

Bare metal stents deliver gene therapy to heart vessels with less inflammation in animal studies

...tients with heart disease, by reducing the risk of inflammation that often negates initial benefits. The new techn...rugs to the stents may stimulate inflammation. The inflammation in turn leads to restenosis. Researchers at The Children's Hospital of Philadelphia have developed ...

How does Mycobacterium tuberculosis infect the lung?

...ung diseases, and 9 had neither active TB nor lung inflammation and served as healthy "controls." The patients underwent a procedure called broncho-alveolar lavage that washes out some of the secretions and cells from the lower respiratory tract. The researchers then analyzed the cells in different ways. They con...

Synthetic Protein Eases Arthritis Symptoms in Mice

... or PLAD, might play a role in thwarting the joint inflammation characteristic of rheumatoid arthritis ?one of the...er from excessive inflammation. A key promoter of inflammation is a chemical called tumor necrosis factor alpha (TNF-alpha). TNF-alpha starts a chemical chain reac...

Scientists show how thinking can harm brain cells

...ed during chronic neurodegenerative diseases. When inflammation occurs in the brain, nerve impulses that are passe...ctivating factor, or PAF, a compound that promotes inflammation and plays many roles in the brain. It can be produced by neurons and takes part in the working of sy...

Stress substantially slows human body's ability to heal

...n-normal levels of IL-6 have been linked long-term inflammation which, in turn, is implicated in a host of age-related illnesses. These include cardiovascular disease, osteoporosis, arthritis, type-2 diabetes, certain lymphoproliferative diseases and cancers, Alzheimers disease and periodontal disease, the resear...

Antibacterial coatings cut infection rates

...s bacteria that settle on contact lenses and cause inflammation and, more rarely, infections," Professor Griesser ...ial colonisation of implants that result in septic inflammation problems. "We are using molecules called furanones, which are derived from natural chemicals origin...

DNA gene vaccine protects against harmful protein of Alzheimer's disease

... when a small percentage of participants developed inflammation of the brain and spinal cord. Injecting the gene, in contrast, caused no brain inflammation in the mice. Dr. Rosenberg said the difference was partly because in the human trial, the protein w...

Infection 'alarm' yields clues to immune system behavior

...une system, for example, can set off the excessive inflammation associated with rheumatoid arthritis and lupus. In...dition, some cancers are more likely to grow where inflammation occurs. These ailments might be helped by a drug that curbs inflammation by reducing the sensitivity...

Chemical warfare agent detection technology used to treat lung disease

...n their breath which relate to the severity of the inflammation in their lungs." NWLRC Consultant Dr Dave Singh, said: "This research could make dramatic improvements to the detection of lung diseases. We are really excited about the future possibilities for diagnosing diseases, and monitoring the response to tr...

Unique equine cataract surgery offered on routine basis

... of intravitreal steroids to control postoperative inflammation of the eye. Professor Knottenbelt said: "This new surgery shows how effectively the latest human cataract surgical techniques can translate successfully to bear on an equine problem. We are pleased that the University can now offer such progressi...

New compound stops brain cell degeneration in Alzheimer's disease

...pound specifically targeted to suppress brain cell inflammation and neuron loss associated with Alzheimer's diseas...ting excessive glial activation can suppress brain inflammation and neuron dysfunction in the hippocampus and protect against cognitive decline in an animal model. ...

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