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Tag: "inflammation" at biology news

Bioartificial kidney under study at MCG

...ntain remaining toxins, electrolytes, mediators of inflammation and such ?removed. The liquid is run through the cell-lined fibers of a second cartridge, while the blood is run on the outside of the fibers. "(These cells) reabsorb substances from the ultrafiltrate ?and put them back into the blood on the outside...

Novel antiviral technology inhibits RSV infection in mice

...y lower levels ofvirus in the lung and less airway inflammation and hyper-reactivitythan untreated mice....

Female sex hormones play a vital role in defense against sexually transmitted diseases

...nally, the progesterone-treated mice had increased inflammation and were more susceptible to the virus. The mice treated with a combination of the two hormones, estradiol and progesterone, were protected, but only if the virus doses were weakened. In the second study, just like in the first study, mice were trea...

Potential Cure for Lymphoma in HIV patients

...entire study due to sideeffects such as nausea and inflammation of the mouth lining. Themajority of patients, though, did resume the HAART therapy soon afterdischarge from the hospital.Although two patients died of relapsed lymphoma a few months aftertransplant, 17 of the 20 patients (85 percent) are currently al...

Research Gives Hope For Liver Damage

...ld explained: "The links between the immunesystem, inflammation and scarring in the liver have not been wellunderstood, and this has hindered progress in finding ways to preventand repair liver damage. Now that we have shown how the macrophageswork, we aim to find out how to create, activate and de-activate these...

Scientists discover that host cell lipids facilitate bacterial movement

...ses, the most severe being meningoencephalitis, an inflammation of the brain and the membranes that envelop the brain and spinal cord. Infection begins when the bacterium binds to a receptor on the surface of a cell, causing the cell to ingest it. The bacterium multiplies inside the cell and then uses a cellular ...

How an AIDS-Related Cancer Unleashes Inflammation

... resulting from kaposin B's binding to MK2 creates inflammation that in turn activates the regulatory protein p38. p38, in turn, further increases activation of MK2. "We still don't know the mechanism by which kaposin B activates MK2," said Ganem. "Nor do we understand how this activation leads to activation of ...

Antibiotic might fight HIV-induced neurological problems

... of the same biological pathways of cell death and inflammation as these other diseases," says Sheila Barber, Ph.D... influx of these cells contributes to swelling and inflammation known as encephalitis. The other protein, p38, helps trigger a series of events that result in a cel...

Artifical cornea lets woman blind 20 years see

...f opacity in the cornea is typically the result of inflammation due to disease. Sometimes it is the result of injuries, like damaging chemicals accidentally introduced into the eye, Afshari added. The artificial cornea is entirely manmade, but does utilize donated corneal tissue, said Afshari. Available devices ...

Rare surgery performed to remove pancreas, prevent diabetes

...rt, surgery to give relief from pain, usually from inflammation of pancreatitis. In the past, such surgery might eliminate the pain but would leave the patient with severe, poorly-controlled diabetes, since the insulin-producing islets of Langerhans would necessarily be discarded along with the rest of the organ....

Researchers report new pro-inflammatory role for anti-inflammatory enzyme

...in an increase in cellular NO which contributes to inflammation and host defense. "NO acts as a cytotoxic/cytostatic effector molecule released (predominantly) by immune cells," explains Dr. Adrian J. Hobbs of University College London. "It kills pathogens via a variety of mechanisms, mostly related to inhibitio...

Test for early detection of prostate cancer shows promise

... injury (seven patients) and noncancerous prostate inflammation (two patients), and 16 healthy individuals. The study was conducted at the University of Pittsburgh while Getzenberg was a member of its faculty. The researchers found that EPCA levels were high in 11 of 12 prostate cancer patients (92 percent) and ...

Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression

... infection they were produced to defeat. Excessive inflammation can lead to organ failure and death, and this is exactly what happens when people are stricken with septic shock. Likewise, the loss of control of genetic expression is the underlying cause of various forms of cancer--for instance the overexpression ...

Owl genomics presents a HEPATOCHIP for diagnosis of non-alcoholic steatohepatitis

... by fatty acid accumulation, hepatocyte damage and inflammation resembling alcoholic hepatitis. NASH is a critical stage in the process that spans from hepatic steatosis to cirrhosis and hepatocarcinoma. NASH is one of the most common causes of elevated aminotransfereases in patients referred for evaluation to he...

Natural Killers Could Lead to New Hepatitis Treatments

...class of immune cell, which is responsible for the inflammation and cell death in the liver due to hepatitis. Hepa...uld offer important insights into the mechanism of inflammation and liver damage due to infections, he said. ...

B cells are required for development of epithelial cancer associated with chronic inflammation

Chronic inflammation is linked to the development of certain types of cancer, but mechanisms mediating inflammation during premalignancy are not well understood. A new research study published in the May issue of Can...

Pair of cancer genes found to drive both cell migration and division

...h inflammatory disorders, such as arthritis, since inflammation is caused when lots of immune cells move to one part of the body and cause it to swell painfully, he says. The researchers also hope their findings will provide a bridge between two scientific fields that have traditionally kept to themselves. "Sci...

Disabling gene defuses rheumatoid arthritis in mice

...so the result of a less specific but still harmful inflammation generated by cells from the other branch of the immune system, the innate immune system." Innate immune cells such as neutrophils respond rapidly to invaders and normally comprise the body's frontline defenses against bacterial infection. Peng beca...

FDA Approves New Treatment for Chronic Hepatitis B

...aclude showed significant improvement in the liver inflammation caused by HBV and an improvement in the degree of liver fibrosis (scarring). In addition, a higher percentage of patients treated with Baraclude showed significant improvement compared to lamivudine. The major adverse events associated with the use ...

Immune system's distress signal tells bacteria when to strike back

...d Alverdy, "then the bug strikes back and then the inflammation process snowballs." Because the bacteria in this case are "normal flora," people with no real infection develop a chronic disease. The battles between pathogens and their hosts have been going on for millions of years, Alverdy said, with each side c...

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