Researchers unravel DNA tangles and enzyme seamstresses
...cations in designing new drugs to treat cancer and infectious diseases as uncontrolled DNA linking and tangling often result in cell death. "The exciting part is that these seemingly abstract physical principles we work with can be useful some day to tie up DNA in cancer cells and kill them off," says U of T ...Research details how a virus hijacks cell signals to cause infection
...lls," said Jeffrey M. Bergelson, M.D., a pediatric infectious diseases specialist at The Children's Hospital of Philadelphia. "We found new steps in the virus life cycle." Dr. Bergelson's study, co-authored with Carolyn B. Coyne, Ph.D., also of Children's Hospital, appears in the Jan. 13 issue of the journal C...Anti-HIV drug has potential to prevent transmission in women
A new study from infectious disease researchers at The Miriam Hospital and Bro...icides," says lead author Kenneth H. Mayer, MD, an infectious disease physician at The Miriam Hospital and professor of medicine and community health at Brown Med...Climate change drives widespread amphibian extinctions
...oof that global warming is causing outbreaks of an infectious disease that is wiping out entire frog populations...the National Science Foundation (NSF)'s ecology of infectious diseases program, which funded the research. "This study demonstrates the complex nature of global c...New test to detect rare proteins in blood
...used as a diagnostic test to determine exposure to infectious agents, such as HIV, by identifying antibodies present in a blood sample. The sensitivity of detecting molecules by the new method, called FACTT, short for Florescent Amplification Catalyzed by T7-polymerase Technique, is five orders of magnitude (...Computer simulation hints at new HIV drug target
...s are cleaved into the parts necessary to assemble infectious virus particles. Structural studies of this cavity helped scientists find the original protease inhibitors. Other scientists are trying to design drugs to bind to the whiskers and or to lock down the flaps by binding to their top. Perryman's first ...Major WHO study concludes calcium supplements can reduce complications during pregnancy
...s are cleaved into the parts necessary to assemble infectious virus particles. Structural studies of this cavity helped scientists find the original protease inhibitors. Other scientists are trying to design drugs to bind to the whiskers and or to lock down the flaps by binding to their top. Perryman's first ...Gut protein found to protect against infection and intestinal breakdown
...stine, a major barrier against the infiltration of infectious microorganisms. That's no small task; if the innermost lining of the small intestine alone were unfolded, it would be the size of a tennis court. When there's no bile in the intestine, as happens in people with obstructive jaundice or in those who r...UCLA paper examines how one disease may prevent another
...vents another. His findings suggest that genetic, infectious and metabolic influences should be considered when looking for treatments, particularly in regard to HIV/AIDS. "Clinical observations of disease-versus-disease interactions have led to an understanding of the mechanisms of several diseases," Stiehm ...New vaccine for condition that kills 500,000 children a year
...Eastern Virginia Medical School (EVMS) and head of infectious diseases at EVMS' Center for Pediatric Research. "In a matter of hours, vomiting and diarrhea from rotavirus can lead to dehydration, which can result in hospitalization and even be life-threatening." Rotavirus causes about 70,000 hospital admission...Study indicates dramatic rise in antibiotic-resistant community-acquired staph infections
...ded first author Mark King, MD, MSc, previously an infectious diseases fellow and faculty member at Emory as well as Dr. Susan Ray, an associate professor of medicine in the Emory Division of Infectious Diseases and Dr. Wayne Wang, a member of the Emory Department of Pathology and Laboratory Medicine and direct...Researchers use mass spectrometry to detect norovirus particles
...ue ideal for situations where you have an emerging infectious agent or pathogenic strain, such as in a potential terrorist attack," said Halden. ...Ancient ants arose 140-168 million years ago
...ue ideal for situations where you have an emerging infectious agent or pathogenic strain, such as in a potential terrorist attack," said Halden. ...US woman gives birth to baby from world's first frozen donor egg bank
...tly reduces any of the current health hazards from infectious disease transmission present when using donor eggs...nors for CEI are tested as required by the FDA for infectious diseases within 30 days of egg collection. Additionally, the eggs are then frozen and quarantined fo...A case of mistaken molecular identity
... mimicry occurs when a molecule that is part of an infectious agent resembles a molecule native to the body. Eventually, the immune system begins to mistake the native molecule for the invader. Levin's investigations revealed that an intra-cellular T. cruzi protein resembles the beta1-adrenergic receptor on t...Inflammation and drugs to control this activity studied in a variety of tumors sites
Inflammation cuts both ways. When invaded by an infectious agent, for example, the body calls on the forces of inflammation to fight and defeat the intruder. But when the biochemical processes of the immune system are either misdirected or chronically turned on, inflammation can lead to adversity, including ...Avian flu modeled on supercomputer, explores vaccine and isolation options for thwarting a pandemic
... In addition, the durations of the incubation and infectious periods can vary and are randomly chosen from dist...rtual laboratories where researchers can study how infectious diseases might spread and what intervention strategies may lessen the impact of a real outbreak," sa...UC Davis study finds HIV hiding from drugs in gut, preventing immune recovery
...the virus," Prindiville said. "You can't treat any infectious disease without the help of the immune system." ...Brittle prions are more infectious
...en seen as a sign of fragility. But in the case of infectious proteins called prions, brittleness makes for a to...re similar to mammalian prions in that they act as infectious proteins. In recent years, mammalian prions have gained increasing notoriety for their roles in such......beginning to realize that the genetic diversity of infectious agents is really important." ...