Researchers develop new testing methods for potential monkeypox or smallpox outbreak
...n about the country's level of preparedness for an infectious disease outbreak that is either naturally occurring or an act of terrorism," said Mark Slifka, Ph.D., lead author and an assistant scientist at the VGTI, an assistant professor of molecular microbiology and immunology in the OHSU School of Medicine a...New results validating Pall prion reduction filter disclosed at ISBT Congress
... May 2005. It is the first technology that reduces infectious prions from red cells, the most widely transfused ...or do we know how many people may be harboring the infectious prions and also donating blood," Ross explained. "Our goal is to work with blood authorities across ...New study finds how cells with damaged DNA alert the immune system
...A damage pathway in regulating immune responses to infectious diseases, but given what we have shown here, it is certainly plausible that it contributes to the expression of the NKG2D ligand," said Raulet. "It may also be that the Rae1 ligand helps trigger T cell responses that contribute to long term specific ...Researcher at UGA College of Veterinary Medicine identifies new way of combating viral diseases
...l of Virology, Thomas Hodge, research professor of infectious diseases at the veterinary college, and his colleagues report that blocking a protein that helps transport viruses out of a cell keeps these four viruses from reproducing and infecting other cells. Most antiviral therapies target the virus itself, b...Renewed hope for Parkinson's patients
...A damage pathway in regulating immune responses to infectious diseases, but given what we have shown here, it is certainly plausible that it contributes to the expression of the NKG2D ligand," said Raulet. "It may also be that the Rae1 ligand helps trigger T cell responses that contribute to long term specific ...UW scientists report a new method to speed bird flu vaccine production
...on because they are not known to carry any unknown infectious agents and do not cause tumors. According to Kawaoka, "application of the new system may be especially advantageous in situations of outbreaks of highly pathogenic avian influenza viruses." When a new strain of highly virulent influenza emerges to ...Stolen gene allows insect virus to enter cells
...t it? These viruses actually generate two types of infectious particles, Blissard explains: one type specialized to infect gut cells, and another that spreads infection in other parts of the insect. The latter type uses F to enter cells. An ancestor of today's baculoviruses "might have just existed as a diarrhe...Grand Challenges in Global Health initiative funds Yale project
...er diseases are made from weakened versions of the infectious agent. These cannot be studied in human trials unless researchers are confident that they are safe. "A big need in the world of vaccine development is the ability to predict whether vaccines for humans are safe and effective," said Flavell. "We are ...Drug resistant avian influenza viruses more common in Southeast Asia than North America
...iseases to permit rapid and accurate monitoring of infectious disease outbreaks globally; and to serve as a cent...ral location for news, updates, and discussions of infectious disease outbreaks that threaten humans. For example, a ProMED transmission on July 6, 2005 noted tha...Hepatitis C complicated by morphine withdrawal
... uses. Although the replicon does not produce the infectious virus, the HCV replicon system represents the best available system for examining the impact of opiates on HCV at the time of their research study. Similar to their previous results, the authors found that MW and PW increased levels of HCV replico...Prions rapidly 'remodel' good protein into bad, Brown study shows
... healthy protein when it comes in contact with the infectious prion form in yeast: The protein converts to the p... the mysterious molecular machinery behind prions, infectious proteins that cause fatal brain ailments such as mad cow disease and scrapie in animals and, in rare...Anthrax stops body from fighting back, study shows
...s, said Dr. Frederick Southwick, division chief of infectious diseases at the UF College of Medicine and the lead author of the paper. "If your neutrophils work normally, you might be able to shut down thisinfection," said Southwick, who worked on the study with a team of UF researchers and investigators from ...UT Southwestern researchers develop screening test for cells that activate immune system
...in identifying biothreat agents because it detects infectious pathogens with high sensitivity. Dr. Takashima said he hopes to garner additional funding to discover potent immuno-stimulatory drugs by screening high-quality libraries of compounds. Doing so may be the first step toward developing a new class o...CO2 sensing proves critical for fungal pathogens to adapt to life in air and human hosts
... which is known to be a key process for generating infectious spores, and the CA enzyme plays a central role in the process. Together with the accompanying work by Mühlschlegel and colleagues, this study implicates a key role for CO2 in growth and differentiation in the fungal kingdom. The identification of a...New vaccine platform may fight infections with causes from influenza to bioterrorism
...nnot be protected against polio, the flu and other infectious agents with existing vaccines that depend on a normal T-cell response. As such, the researchers were motivated to develop CD4+ T-cell–independent therapeutic strategies to meet this growing need. "While we'll need to replicate these findings in lar...Mechanism for Epstein-Barr virus protein's role in blood cancers discovered
... carcinoma, and also causes the well-known disease infectious mononucleosis. As many as 95 percent of adults 20 years and older have been infected with EBV, but show no symptoms. Now, the researchers are in the process of blocking the molecular signals caused by EBNA3C's presence in B cells. This points the w...Pillows - a hot bed of fungal spores
...ing condition Aspergillosis has become the leading infectious cause of death in leukaemia and bone marrow transplant patients. Fungi also exacerbate asthma in adults. The researchers dissected both feather and synthetic samples and identified several thousand spores of fungus per gram of used pillow - more tha...Scientists pinpoint inflammation gene
...ease, diabetes, obesity, preeclampsia, and various infectious diseases. Kissebah said it provides new insight into studies he leads on the genetics of obesity. "Now that we have identified SEPS1' role in inflammation, which is known to initiate the process of arterial wall hardening and the onset of Type 2 dia...SLU researchers uncover direct evidence on how HIV invades healthy cells
... processes viral proteins and is essential to make infectious virus. Drugs such as AZT and drug combinations (cocktails) exist to inhibit reverse transcriptase and protease. As of yet, there are no drugs to counter integrase. By using a biophysical methodology known as Fluorescence Resonance Energy Transfer...Breaking the mold: Research teams sequence three fungus genomes
...ffer--or do not even occur--in a similar, yet less infectious fungus, Neosartorya fischeri . Nierman and colleagues are now searching these unique genes for clues to A. fumigatus infectivity. It's a complex task. Suspect genes encode proteins involved in central metabolic pathways, cell signaling, cell wa...