Worms produce surprise insight into human fever
...insight into another classic metazoan response to infection fever. The first pathway was p38 MAPK/CED-3, w...ions. But the mechanism of fever as a response to infection is still largely unknown. The activation of the HSF-1 pathways by heat shock and its function in C....New HIV statistics indicate increasing toll of AIDS on African American community
...g needle-exchange programs to minimize the risk of infection from sharing needles. Expand proven HIV prevention, diagnosis and care programs. ?Far too many African Americans lack accurate information about how HIV is transmitted, prevented and treated. Approximately 250,000 Americans ?many of them African...Researchers discover key mechanism by which lethal viruses Ebola and Marburg cause disease
...sociated with fever, shock, and bleeding caused by infection with one of a number of viruses, including the Fil...Ebola virus. Immunosuppression occurs early after infection and allows the viruses to reproduce rapidly and cause disease. "Currently, there is no way to trea...High HPV concentrations combined with smoking significantly raise risks of cervical cancer
Cigarette smoking and concurrent infection with high levels of the virus associated with cervical cancer can increase cancer risk by as much as 27 times, according to a study published in the November 2006 issue of Cancer Epidemiology, Biomarkers & Prevention. Anthony Gunnell, a medical...Special chip provides better picture of salmon health
...s in the wild. They are particularly vulnerable to infection because of the dramatic physical and chemical changes they go through, known as smoltification, which enable them to live in both fresh and salt water. Assessing their health and performance is very difficult as conventional measures used in other an...UCSD researchers discover internal compass of immune cell
...une defense against bacteria ?navigate to sites of infection and inflammation. These findings could potentiall...t and migrate towards chemoattractants, markers of infection and inflammation that are released from bacteria and inflamed tissues. "These findings solve the l...HIV exploits competition among T-cells
...model accurately describes all three phases of HIV infection by incorporating a key component: competition amon...immune cells produced in response to a first viral infection to suppress the creation of new immune cells in response to a second infection by a related strain. ...New mechanism underlying pain found
...ury, typically results from a traumatic injury, an infection or disease, or surgery, and can persist long after the initial injury has healed. Millions of people worldwide suffer some form of neuropathic pain, and the current treatment options are limited or inadequate for many people. The research presented t...Twenty Years of Malaria Research: Outcomes and Perspectives
...nce network established in 1995 to monitor malaria infection in the camps along the border has now received funding to track the development of the avian influenza virus. ...Flu shot effective against drifted influenza, nasal spray vaccine less so
...ke illness," or measures of the immune response to infection in the blood. For the present study, Monto and lead author Suzanne Ohmit, assistant research scientist in epidemiology, took throat swab specimens from participants experiencing flu symptoms and analyzed them, using virus isolation and PCR technique...Common cold virus leads to death in lung transplant patients
...ts who suffered clinically significant respiratory infection from HRV in both the upper and lower airways, over...iates assessed the incidence of chronic rhinovirus infection and its potential clinical impact on 69 lung transplant recipients at two centers. Over a 19-month p...Effective HIV control may depend on viral protein targeted by immune cells
...nse of the immune system’s ‘killer?T cells against infection with HIV may depend on exactly which viral protein...esponse would probably translate into asymptomatic infection for more than a decade, compared with progression to AIDS within two to three years of infection in ...Dragonfly's metabolic disease provides clues about human obesity
...der's dragonflies, the reverse happens. Parasitic infection triggers an inflammatory response and immediate changes in metabolism. Unable to metabolize fat, the dragonflies accumulate fat around their muscles. This finding begs the question of whether something similar might be happening in human metabolic ...Quality not quantity important for immune response to HIV
...ing first identified in 1981, a vaccine to prevent infection has so far proved elusive. When HIV infects the body, it hides out in so-called "helper T-cells". T cells play an important role in the immune response generated by the body to fight infection. There are a number of different types of T cells, eac...Gene chip technology shows potential for identifying life-threatening blood infection
... rapid way to diagnose sepsis, a fast-moving blood infection that is a leading cause of death in hospital inten... in a few hours determine if a patient had a blood infection and treat them right away." Such a test could not only be used in intensive care units but also i...High levels of blindness in southern Sudan following years of war
...en aged less than 15 years. The earliest stages of infection were very common indeed, particularly in children ...itions, better hygiene, and early treatment of the infection with antibiotics can prevent trachoma. Surgery for trichiasis is also very effective. The World Heal...Researchers map spread of pathogens in the human body
...fficulty of identifying and observing directly the infection process within live tissues. For this study, the Cambridge researchers used advanced fluorescence microscopy techniques to observe intracellular growth of Salmonella bacteria within living cells....Tuberculosis: The bacillus takes refuge in adipose cells
...nts and for people with AIDS, for whom a secondary infection with tuberculosis bacillus may have very serious consequences. This work highlights the importance of the search for new targeted therapeutic weapons, such as new antibiotics, which must be able to reach the dormant bacillus that has been hiding in...Human testis harbors HIV-1 in resident immune cells
... of human testis to human immunodeficiency virus-1 infection in situ and in vitro,?appears in the December issu...inued to secrete testosterone, was able to support infection by HIV-1. Virus produced from the testis culture was fully active as collected virus was able to inf...Mayo Clinic study suggests that a central nervous system viral infection can lead to memory deficits
...t explores memory deficits associated with a viral infection of the central nervous system, Mayo Clinic researchers have evidence that this infection can lead to memory loss late in life. The study, which was conducted in animal models, suggests that...