A first glimpse of the influenza replication machine
...bute to transmission of avian flu to humans. Upon infection the influenza virus starts multiplying in the cells of an infected host. The polymerase is crucial in this process because it copies the viral genome and directs the production of its proteins. Interfering with polymerase function would prevent the v...Common parasitic infection leads to increased risk for HIV infection
... study shows a significantly increased risk of HIV infection among women with a common sexually transmitted dis...negative women over the span of 11 years. Because infection with T. vaginalis is common, even a modest increase in vulnerability to HIV acquisition as a result ...Swimming 'to the left' gets bacteria upstream, and may promote infection
...id Köser. "It might also explain the high rates of infection in catheterized patients and the incidence of microbial contamination at protected wellheads. To our knowledge, this is the first time that a natural propensity to swim upstream has been discovered and described in bacteria." To study the hydrod...Minuscule molecules pack a powerful punch
...oimmune disease. They are also less able to resist infection by bacteria, such as Salmonella. The team suggest ...ficant: the knockout mice were less able to resist infection by bacteria than mice with normal miR-155, producing lower levels of antibody and a reduced response...New test helps identify hepatitis C patients at high risk of developing cirrhosis
...cording to the American Liver Foundation. Chronic infection can lead to the severe scarring known as cirrhosi...ult in liver cancer or liver failure. Hepatitis C infection is the most common reason people need a liver transplant in the United States and is responsible f...Opening windows may be the best way of preventing transmission of airborne infection
... what these results might mean for transmission of infection and estimated that in mechanically ventilated rooms 39% of susceptible individuals would become infected following 24 h of exposure to untreated TB patients compared with 33% in modern and 11% in pre-1950 naturally ventilated facilities with windows ...New approach could lower antibiotic requirements by 50 times
... more than 8,000 people in the UK every year. MRSA infection can lead to septic shock and death. ...Investment level in HIV prevention programs related to HIV incidence in the United States
... period, society responded to increasing levels of infection with more investment in prevention programs. Things changed in the mid 1980s when investment levels began to predict incidence. That is, as the nation continued to increase the funding of HIV prevention programs, HIV dropped substantially from 160,00...Widely used hepatitis B drug spurs HIV drug resistance
...reating hepatitis B first," she adds. Hepatitis B infection attacks the liver and can lead to cirrhosis, liver...d patients decide first to treat their hepatitis B infection if HIV has not yet weakened their immune system and to avoid the debilitating side effects of anti-H...Common cold virus may kill breast cancer cells
...de effects as harmless as a mild, common cold-like infection yet it could successfully treat breast cancer," Ms Skelding said. Latest research to be revealed at Canberra briefing The Skelding project, and other ground-breaking research, will be discussed at the NBCF Annual Breakfast Briefing, a series of...Temple University Hospital investigates treatment for cervical dysplasia
...preventive vaccines may lower the incidence of HPV infection and reduce the risk of cervical cancer," said Enri...ion, have not demonstrated effectiveness after the infection has progressed to cervical dysplasia," Hernandez explained. For women diagnosed with high-grade ...Salmonella survives better in stomach due to altered DNA
...f DT104 that might be involved in its survival and infection mechanism. This genetic information might also be ...r hand are only active in the intestines where the infection takes place. Evolution of the pathogen The DNA of the pathogen says something about how it...Prion disease treatable if caught early
...s in the prion field," they wrote. "To date, prion infection in mice has conventionally been diagnosed when motor deficits reflect advanced neurodegeneration. Now the identification of earlier dysfunction helps direct the study of mechanisms of neurotoxicity and therapies to earlier stages of disease, when res...ASU researchers test antibacterial effects of healing clays
...as aeruginosa (often a problem as an opportunistic infection in burn wards) and Mycobacterium marinum (related to Mycobacterium ulcerans, which causes Buruli ulcer disease). The clay was also found to partially inhibit the growth of pathogenic Staphylococcus aureus, including a multi-drug resistant variety. "T...Gladstone investigators identify a new protective action for the powerful anti-HIV factor, APOBEC3G
...eted by HIV -- are sometimes so susceptible to HIV infection and at other times are highly resistant. Scientists have known that resistant CD4 T cells, called "resting cells," are made up predominantly of CD4+ T cells that are in an inactive state, awaiting a stimulus to move into action. In these cells, A3...New study aims to stop sepsis in its tracks
...overy. That's not the case if you have a body-wide infection known as sepsis, which can be fatal within a few h...epsis occurs when the body's normal reaction to an infection goes into overdrive, causing widespread inflammation and dramatic changes in body temperature, blood...Interaction between lymph and liver cells may affect immune response
...l activation in the liver during early hepatitis C infection may contribute to the impaired immune response seen in chronic hepatitis C. "As well as providing insight into the normal immune system, our observations might have implications for liver conditions associated with altered LSEC morphology and in p...Early-stage immune system control of HIV may depend on inherited factors
... system controls HIV during the earliest phases of infection appears to depend on both the specific versions of...m HIV-1 are targeted by the immune system in early infection and that the versions of HLA Class I previously associated with slower HIV-1 disease progression als...UCSF study will test new vaginal microbicide for herpes and HIV
...se it would allow women to protect themselves from infection rather than relying on their partners to use condo...cent Medicine at UCSF Children’s Hospital. "Herpes infection is the number one attributable cause of HIV infection in the United States and worldwide." The ge...