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Tag: "infect" at biology news

Basis for DNA ejection from single phage particles

...d in most eukaryotic viruses, including those that infect humans, in that the envelope of these viruses fuses with the host plasma membrane so that the genome is delivered without directly contacting the membrane. Phage nucleic acid transport poses a fascinating biophysical problem: Transport is unidirecti...

Researchers identify protein crucial for survival of Lyme-disease bacterium

...it can't maintain itself in nature and hence can't infect animals or humans." UT Southwestern molecular microbiology graduate student Andrew Revel, a lead author of the study, found the bptA gene by screening a number of candidate genes he thought might be affecting the survivability of Bb within its hosts...

Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection

...gests that the ability of prions in one species to infect other species depends on the shape of the toxic th...earch suggests that prions from one species rarely infect other species, some scientists believe the species barrier was breached when a new version of Creutz...

Reducing malarial transmission in Africa

...s of gametocytes carried and how able they were to infect mosquitoes 7 days later was also reduced by the six dose regimen. Although the results are promising, some patients may have difficulty taking a six-dose regimen, and as it also needs oily food for adequate absorption there might be inadequate drug ...

Viral protein influences key cell-signaling pathway

...arlier study, Lairmore and his colleagues tried to infect an animal model with an HTLV-1 that lacked the p12 gene, and it stopped the virus from replicating almost entirely. "That told us this gene was important," he says. Subsequent research led by Lairmore showed that the p12 protein travels to the netw...

Norovirus, AIDS vaccine and Hepatitis Virus

...y. Hepatitis B (HBV) and C (HCV) are viruses that infect the liver, and in some cases can cause liver failure requiring a transplant for survival. The protein interferon, produced by animal cells when they are invaded by viruses, is released into the bloodstream or intercellular fluid to induce healthy cel...

NYU study reveals how brain's immune system fights viral encephalitis

...eins, and blocking the virus' release, which could infect other cells in the brain. "There is no magic bull...s from forming particles which can be released and infect other neurons. This is critical, since the immune system does not kill infected precious neurons the...

A new study examines how shared pathogens affect host populations

Many pathogens are able to infect multiple species within a community and are common...laria, Lyme disease or West Nile encephalitis that infect multiple hosts are commonly transmitted by vectors, and their transmission rate is often thought to ...

Yale researchers identify molecule for detecting parasitic infection in humans

...nd other eukaryotic organisms. When microorganisms infect humans, the atypical molecules are usually detected immediately by human proteins called Toll-like receptors (TLR) that alert the human immune system to fight the infection. But parasites, like humans, are eukaryotic in origin and how the body detec...

Mayo Clinic Researchers Create 'Obedient Virus'; First Step To Use Measles Virus Against Cancer

... may be a little too promiscuous in its ability to infect both cancer cells and non-cancer cells, so we want...op a method whereby we could retarget the virus to infect cancer cells only," says Dr. Russell. "And we succeeded." ...

Protein offers way to stop microscopic parasites in their tracks

...educing the parasite's ability to move and thereby infect a host. A postdoctoral researcher in Sibley's lab, Fabien Brossier, Ph.D., decided to try to use the recently completed Toxoplasma genome to search for the protein that lets the parasite detach glue spots at the back of the belt. Scientists led by t...

Antibiotic might fight HIV-induced neurological problems

...tissues in the same way and use the same tricks to infect cells and outwit treatments, but SIV infects only non-human primates, and HIV only infects people. Antiretroviral drugs target and interfere with the viral proteins needed to accomplish this. In contrast, minocycline doesn't target the virus or its ...

UCSD discovery may help extend life of natural pesticide

...undworms that parasitize humans. "These parasites infect nearly one-third of the human population and pose a significant health problem in developing countries," said Aroian. "Perhaps one-day vertebrate-safe Bt toxins could be used as human therapies against these parasites." Griffitts and Aroian credit t...

Antibodies from plants protect against anthrax

...imal pathogens, and plant viruses are not known to infect humans," says Yusibov. "It is an easy, inexpensive and, very stable system. If you're looking for a way to stockpile a large amount of antibodies for a long periods of time, plant-produced antibodies are the answer," says Baillie. Anthrax antibodie...

UCLA scientists transform HIV into cancer-seeking missile

...e AIDS had been removed. This allowed the virus to infect cells and spread throughout the body without provoking disease. "The disarmed AIDS virus acts like a Trojan horse ?transporting therapeutic agents to a targeted part of the body, such as the lungs, where tumors often spread," said Chen, a professor ...

Studies reveal methods viruses use to sidestep immune system

...e two studies, said the tactics employed by HCV to infect a host are likely to be similar to those employed by other RNA viruses such as West Nile, influenza and the common cold. "This work has broad implications that go beyond just the hepatitis C virus, and that's what we're most excited about," said Dr....

New comparative toxicogenomics database

...IgR and enters the blood, whereit can multiply and infect the body. S. pneumoniae is the only bacterium known to use CbpA to invade humancells by binding to pIgR, according to Richard W. Kriwacki, Ph.D.,associate member of St. Jude Structural Biology. Kriwacki is seniorauthor of the EMBO Journal report.“Th...

Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine

...IgR and enters the blood, whereit can multiply and infect the body. S. pneumoniae is the only bacterium known to use CbpA to invade humancells by binding to pIgR, according to Richard W. Kriwacki, Ph.D.,associate member of St. Jude Structural Biology. Kriwacki is seniorauthor of the EMBO Journal report.“Th...

NYU Study Reveals How Brain's Immune System Fights Viral Encephalitis

...eins, and blocking the virus' release, which could infect other cells in the brain. "There is no magic bull...s from forming particles which can be released and infect other neurons. This is critical, since the immune system does not kill infected precious neurons the...

Newly discovered virus linked to childhood lung disorders and Kawasaki disease

...is one of thenumerous coronaviruses, most of which infect animals. In humans,coronaviruses have been known primarily for causing colds or, morerecently, severe acute respiratory syndrome (SARS). Genetic evidencenow suggests that a previously unknown coronavirus may account for someof the many respiratory di...

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