UQ scientists break new ground in fight against infection & chronic disease
... Professor Stow said when disease-causing microbes infect the body, macrophages respond by engulfing and killing the microbes. "The cells also release chemical messengers to boost immunity," Professor Stow said. She said the research was made possible by advanced technologies at the IMB such as live cel...On a wing and a prayer - Alaska researchers seek clues to bird flu
... many influenza viral strains that normally do not infect humans. However, recent outbreaks of bird flu in Southeast Asia were caused by a highly pathogenic H5N1 strain and there is increasing evidence that this strain can jump the species barrier and cause severe disease and mortality in humans. A second a...Purdue researchers find key to rice blast fungus
...genes, the fungus couldn't develop appressoria and infect the plant. The pathway holds enormous potential of being used to produce new fungicides or new resistant rice plants to hold this pathogen at bay. However, rice blast fungus is able to quickly evolve new tricks to tackle rice plants, apparently beca...Stolen gene allows insect virus to enter cells
...he virus to penetrate the host cell's membrane and infect it. Scientists had shown that some other viral gen...ticles, Blissard explains: one type specialized to infect gut cells, and another that spreads infection in other parts of the insect. The latter type uses F t...New book expands biological classifications to account for 'alien' life
...ard argues are as alive as the many parasites that infect humans and other organisms. The revamped classification system also would include life based on RNA instead of DNA, and life found away from Earth that likely would be based on silicon or elements other than the carbon-hydrogen-oxygen-nitrogen mixtur...UW scientists report a new method to speed bird flu vaccine production
...hinery to make new virus particles, which go on to infect other cells and make yet more virus particles. Va...new strain of highly virulent influenza emerges to infect humans, vaccine makers must tailor their vaccines to match it because, genetically, the virus is alw...Scientists use gene transfer technology and common virus to block neuropathic pain
...t make it possible for the herpes simplex virus to infect a human host, VA/U-M scientists use it as a carrier to deliver GAD to the nucleus of nerve cells in the dorsal root ganglion near the spine. In previous studies, the researchers have confirmed that the vector remains in the dorsal root ganglion, but ...Scavenger cells could be key to treating HIV-related dementia
...her populations of slightly different viruses that infect different parts of the brain, the findings show. "We agree there are different strains that populate different regions of the brain," said Francisco Gonzalez-Scarano, M.D., chairman of the University of Pennsylvania neurology department. "We've done...UCLA scientists reveal how Nipah virus infects cells
...?a danger level equivalent to the Ebola virus. To infect a cell, viruses must bind to a viral-specific rece...cells vulnerable to the Nipah virus, but could not infect Nipah-resistant cells. In the final step, the decoy virus entered nerve cells and cells lining bloo...Learning how SARS spikes its quarry
...rus to fuse with a host cell and inject its RNA to infect the cell. A detailed understanding of how the sp...s at those sites can affect the virus's ability to infect humans. Such mutations enable viral transmission by altering the shape of the spike protein, which a...Virus uses tiny RNA to evade the immune system
...ifornia, San Francisco. Ganem studies how viruses infect people and cause disease. When scientists found that RNA interference appeared to be a basic and widespread gene regulatory mechanism, "it became clear that such a fundamental pathway could of course be pirated by a virus," said postdoctoral fellow A...How HIV disables the cells' call for help
...e host DNA later break out of the cell membrane to infect other cells. Many believed that the very act of br...nger to patients as it lacks any ability to either infect cells or to reproduce. Rather, as the scientists note in their paper, the study of a destructive vir...Scientists use gene transfer technology and common virus to block neuropathic pain in animals
...t make it possible for the herpes simplex virus to infect a human host, VA/U-M scientists use it as a carrier to deliver GAD to the nucleus of nerve cells in the dorsal root ganglion near the spine. In previous studies, the researchers have confirmed that the vector remains in the dorsal root ganglion, but ...Mosquito study shows new, faster way West Nile can spread
...ingle bite from a donor mosquito was sufficient to infect two out of 87 recipient mosquitoes. The discovery calls into question the current conception of mosquito transmission of West Nile virus and possibly other viruses such as the one that causes dengue fever. According to that theory, many vertebrates ...Researchers discover how malaria parasite disperses from red blood cells
... and releases them. The newly released merozoites infect still other cells, and the process begins again. To conduct the study, the researchers stained red blood cells infected with P. falciparum with two kinds of dye, explained the study's senior author, Joshua Zimmerberg, M.D., Ph.D., Chief of NICHD's...Secret sex life of killer fungus?
...trains with increased ability to cause disease and infect humans. Nevertheless, the sexual cycle could be a useful genetic tool for scientists to use in their study of the mechanisms by which the fungus causes disease. Further work is now aimed at seeing if the fungus can truly reproduce by sexual means. ......he hybrid contains no Ebola genes - and HIV cannot infect lung cells. If it did get into the blood, where no...ould never reach high enough levels in the body to infect others, Pickles says. The biggest risk is that if a patient becomes infected with wild-type HIV, th...Several minute intermediate stage in virus-cell fusion discovered; opportunity for drug development
...cases in which the pore does not open, it fails to infect the cell at all. "It's like a space craft docking on a space station," said Young. "If you try to open the inner door before the pressures have equalized, you can tease it open a little bit but it keeps closing on you until there's enough pressure i...Researchers create infectious hepatitis C virus in a test tube
...d replicates and produces virus particles that can infect new cells, initiating replication in them and lead...nents before being released from the liver cell to infect other cells. Lindenbach, Rice and their colleagues named their infectious cell culture virus HCVcc....Gene discovery sheds light on causes of rare disease, cancer
...isteria's use of receptor-mediated endocytosis to infect hosts, according to Cossart, suggests that other bacteria may exploit the same mechanism to gain entry into non-phagocytic cells. "This mechanism of cell entry may be used by several different kinds of bacteria, which is a major deviation from the be...