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Tag: "infect" at biology news

Scientists identify molecular structure of key viral protein

...icture of how the paramyxovirus F protein works to infect the cell. The F protein belongs to a group of fu...etic information into the cytoplasm of the cell to infect it." In the process the protein moves from its first folded state, the metastable state (pre-fusion...

Drug-resistant bacteria patterns in intensive care units changing nationally

... infections are the most common, but MRSA can also infect the heart, the lungs, and the digestive tract. The...nd mortality." Due to community MRSA's ability to infect the young and healthy, traditional risk factors for identifying hospital-associated MRSA colonizatio...

Virginia Bioinformatics Institutes launches microbial database

...gen Hyaloperonospora parasitica, both of which can infect the model plant Arabidopsis. In addition, support for proteomic and microarray data will be added, which will be linked to the functional genomic data and the genome sequences. P. ramorum, also known as sudden oak death, is a serious fungal pathogen...

Genetic mutation linked to West Nile virus infection

...identified in 1996 as a co-receptor used by HIV to infect cells. Individuals with two copies of this mutation (CCR5delta32) are highly resistant to HIV infection, even when repeatedly exposed to the virus. This resistance was the theoretical basis for the development of therapeutic CCR5 inhibitors, severa...

Worm hormone discovery may aid fight against parasitic disease

...g to the World Health Organization, such parasites infect about 2 billion people worldwide and severely sicken some 300 million, at least 50 percent of whom are school-age children. In the infective state, parasitic nematodes, such as hookworms, remain in a larval, "resting" stage until they enter the hum...

New antimicrobial compound adheres to skin to promote healing

...s, whether animal or human, bacteria and fungi can infect the open wounds and kill the patient," Ritchie said. "We have found a way to kill those drug-resistant bacteria and fungi with compounds that cleanse wounds while being gentle on the tissue." Combining Tricide with a bioadhesive came about as a res...

U of S researchers develop new vaccine candidate against hepatitis C

...ected into mice as a vaccine. Because HCV does not infect mice, mice were challenged with a carrier virus containing the hepatitis C protein. The levels of HCV protein in immunized mice using this model were five orders of magnitude lower than the control. ...

Biologists visualize protein interaction that may initiate viral infection

...use different biological mechanisms than dengue to infect host cells. Dengue is prevalent in Southeast Asia, Central America and South America. Mosquitoes transmit the virus to people, setting in motion the infection process. "We and others think that this CRD acts sort of like Velcro to get the virus to s...

A new way of looking at molecular motors

...o the other. Myosins also help parasites enter and infect hosts. Defects in the motors play a role in a variety of human and animal disorders, including retinitis pigmentosa (which causes blindness), polycystic kidney disease, brain development defects, neurodegenerative diseases, muscular dystrophy, skin p...

Access to antiretrovirals unlikely to reduce HIV infection rates

... take them, but also make it less likely that they infect others. As a consequence, ART has been discussed not only as a treatment but also as a prevention tool in its own right. To test this, Baggaley and colleagues used a model to predict and compare the impacts of alternative strategies of increasing A...

Research details how a virus hijacks cell signals to cause infection

...ural barriers, then exploits biological signals to infect human cells. Broadening knowledge of how viruses c...tudy helps to explain how group B coxsackieviruses infect cells," said Jeffrey M. Bergelson, M.D., a pediatric infectious diseases specialist at The Children'...

Researchers reveal lung's unique innate immune system

...in combating any novel microbial agents that could infect the lower airways, such as a new flu strain or bioterrorist agents," said Raz. The researchers' data outlines a complex circuit in which the alveolar macrophages circumvent the inhibition by TGFb for brief period of time, in order perform their im...

Hantavirus found in African wood mouse

... preliminary evidence that the Sangassou virus can infect humans, because we identified hantavirus-specific neutralizing antibodies in [the blood] of humans living in the area where the virus was detected. We do not know if these people suffered from an HFRS-like illness, but studies to determine this are i...

Wisconsin scientists find a way to make human collagen in the lab

...ents and it can harbor animal pathogens that might infect humans. The Wisconsin team discovered a way to make the long, slender collagen molecules, in essence, by having the protein assemble itself. What was required, Raines explains, was a way to give the collagen snippets that scientists could easily mak...

Animals can change genes quickly to keep up with viral ingenuity

...amous for evolving quickly, but the organisms they infect can't be expected to sit idly by. There is now new evidence that animals in fact do an impressive job of keeping up in the ongoing evolutionary arms race between viruses and their hosts. Studying a special class of genes thought to have evolved in pa...

Newly discovered protein kills anthrax bacteria by exploding their cell walls

...al predators called bacteriophage. Just as viruses infect people, bacteriophage infect bacteria, reproduce, and then kill their host cell by bursting out to find their next target. The ba...

Ticks, flukes, and genomics: Emerging pathogens revealed

...overed a clue to how ehrlichiosis-causing bacteria infect such diverse animals. One of the three primary bac...ds. "Now we know how some of the pathogens studied infect or provide benefits to their hosts." The scientists hope to build on this work, with potential stud...

New hybrid virus provides targeted molecular imaging of cancer

...acterial virus (phage). Unlike animal viruses that infect mammalian cells, bacterial viruses have evolved to infect only bacterial hosts. The paper shows how particles of the hybrid virus, called AAV phage or AAVP, c...

Waking a sleeping virus

...others are necessary to produce new viruses and to infect new host cells. Those have to be switched on, and ZEBRA functions as the switch which turns the cell into a factory to manufacture thousands of copies of the virus." One result is the disease infectious mononucleosis ?called the "kissing disease" b...

Scientists a step closer to protecting world's most important crop

...e rice-killer hijacks its plant prey. In order to infect plants the fungus has to inject its proteins into the plant's own cells where they overcome the plant's defences allowing a full scale invasion by the fungus. Until now it's not been known how the fungus delivers that weaponry, but researchers from ...

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