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Tag: "infect" at biology news

Carnegie Mellon scientists find key HIV protein makes cell membranes bend more easily

...embrane to bend, making it easier for the virus to infect immune cells. The finding, in press in Biophysical...on could provide a general way that viruses use to infect cells, so it will be exciting to look at other viral systems with our experimental method,” she said...

How sneaky HIV escapes cells

...ng transport system to leave one infected cell and infect new ones, Hopkins scientists have discovered. Thei... rely on exosomes to get out of infected cells and infect fresh cells. As such, drugs that interfere with exosome formation might be one way to inhibit HIV in...

Largest synthetic gene ever built offers insights into anti-malarial drug resistance

...ies of malaria parasites, according to Roepe. Five infect humans, but P. falciparum is responsible for about 1 million deaths out of 300 million acute cases of infection each year. Most of these deaths occur in young children living in sub-Saharan Africa. Roepe and his collaborators at Georgetown Univer...

New bacterium discovered -- related to cause of trench fever

...discovery is the sixth species identified that can infect humans, said Jane Koehler, MD, professor of infectious diseases at UCSF and senior author on the new paper. Koehler encountered her first patient infected with Bartonella in 1987 during her first week of training in infectious diseases at the AIDS...

Blood-brain barrier breached by new therapeutic strategy

...l School in Boston, and his colleagues used JEV to infect the brains of mice. They then injected the antiviral siRNA bound to the rabies peptide through the tail veins in one group of mice, while other mice served as control groups. All the mice in the control groups died from JEV infection; in contrast, 80...

Researchers discover 'acquired' DNA key to certain bacterial infection

... avium exists in the environment and is thought to infect humans when the infected environmental hosts – amo...come from a pathogen which also has the ability to infect environmental amoeba....

Revealed -- Mosquito genes that could be controlling the spread of killer viruses

...hat cause yellow and dengue fevers – diseases that infect over 50 million people worldwide every year. This study is the first of its kind on the newly-sequenced genome of the Aedes aegypti mosquito, which is also published in this week’s Science. The researchers identified over 350 genes which are invo...

Ancient retrovirus sheds light on modern pandemic

...ing against any of the retroviruses that currently infect humans, such as HIV-1," Emerman said. "In the end, this drove human evolution to be more susceptible to HIV." For example, the researchers found that changes in TRIM5a that make it better at fighting HIV actually inhibit its ability to stop PtERV1 an...

New vaccine prevents CMV infection and disease in mice

...ople remain infected and can become re-infected or infect others through saliva. “Children in day care settings, for example, or adults who are sexually active, can pass along the virus,” explained Spector. “It becomes a serious problem in developing infants during the pregnancy or in those whose immun...

Vaccine prevents prion disease in mice

...lso reduces the possibility that the disease could infect humans. ...

WHO data confirms low level of resistance to Tamiflu

... inhibited, the virus is not able to spread to and infect other cells in the body. It is licensed for the treatment and prophylaxis of influenza in children aged one year and above and in adults. ...

Dealing deadly cancers a knockout punch

...ses the cell to burst, which releases viruses that infect and kill adjacent cancer cells. Normal cells are not harmed. In addition to killing cancer cells directly, reovirus is believed to activate an anti-tumor immune response through the body's natural killer cells and T cells. Through this mechanism,...

Herpes infection may be symbiotic, help beat back some bacteria

...mous herpes viruses like HHV6 and HHV7 permanently infect most humans without ever producing any significant..., which is a minor cause of food poisoning and can infect the central nervous system. Many aspects of Listeria infection in mice are also similar to those tha...

The quest for an effective HIV vaccine presents new possibilities, challenges

...y and late stages of infection--are most likely to infect their sexual partners. A preventive vaccine given ...ls and potentially reduce that person’s ability to infect other people, Drs. Johnston and Fauci assert. Vaccines of this type present several complication...

Deconstructing brain wiring, one neuron at a time

...e rabies virus ?now acting like a bird virus ?will infect them. "The bottom line is that you need two gen...rus protein, allowing the modified rabies virus to infect targeted cells and spread only once to connecting cells," he adds. The wiring map can be constructed...

Researchers wake up viruses inside tumors to image and then destroy cancers

...m molecular-genetic imaging, we have always had to infect cells with active herpes simplex virus so that they can replicate, express TK, and only then could we use the FIAU tracer to make the cells light up," Pomper says. "So we were hoping to find a way to turn latent Epstein-Barr virus on in these cancers...

UCI scientists reconstruct migration of avian flu virus

...evolution of different H5N1 strains lets the virus infect and cycle through different host species in a region, regardless of the host or vector species it infects first. This way, the virus can find the right host to spread the infection to the next location. This parallel evolution ?the independent evolut...

Study finds antibiotic resistance in poultry even when antibiotics were not used

...n is that drug resistance genes from bacteria that infect poultry could be passed on to bacteria that cause human illness. With these resistance genes, human bacterial illness could become harder to treat. These concerns led the European Union to ban the use of antibiotics for growth promotion in chicken...

Discovery could lead to better control of hemorrhagic fever viruses

...ngs, Choe's team found that New World arenaviruses infect cells more efficiently when iron levels are low, and that adding iron to cultured cells makes them less susceptible to infection. Choe notes that New World hemorrhagic fever outbreaks mostly occur in poor rural areas, where people are often deficient...

Cold sore virus might play role in Alzheimer's disease

...adhesion molecule that herpes uses as one route to infect a cell. Nectin-1 plays a crucial role in forming synapses, the structures between brain cells that move information and signals from one cell to the next. The team is studying whether herpes somehow disturbs the receptor, possibly altering the struct...

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