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Tag: "inducing" at biology news

Seaweed yields new compounds with pharmaceutical potential

... by the researchers -- killed human tumor cells by inducing programmed cell death (called apoptosis), a mechanism that is promising for development of new anti-cancer drugs, researchers noted. The findings on three of these compounds ? called diterpene-benzoate natural products -- are reported in the Oct. 12...

PET imaging reveals the immune system at work

... with genes engineered to be detectable by PET. By inducing cancer in the mice, Witte and his team were then able to observe specific immune cells at work as they reacted to the tumor. "The fact that we can visualize the cellular immune response without invading the body is an important advantage," Witte not...

Jefferson biologist coaxing human embryonic stem cells to make dopamine with simpler, faster method

... with genes engineered to be detectable by PET. By inducing cancer in the mice, Witte and his team were then able to observe specific immune cells at work as they reacted to the tumor. "The fact that we can visualize the cellular immune response without invading the body is an important advantage," Witte not...

Human trial proves ricin vaccine safe, induces neutralizing antibodies; further tests planned

...in humans, exposure by aerosol or food may require inducing immunity in the lung and gut by a very different formulation and vaccination schedule. Depending on how the ricin is administered as a poison, victims develop fever, nausea and abdominal pain or lung damage before dying within a few days of exposure...

Growth factor-promoting angiogenesis expressed in tumor cells and normal neurons

... following brain injury promotes tumor survival by inducing angiogenesis. The research study, published in the...rgical biopsies or partial tumor resections may be inducing a proangiogenic response, or trigger, within the brain," cautions Dr. Fine. ...

Brain's own cannabis compound protects against inflammation

...n studies with mouse brain slices, they found that inducing damage with a brain-cell-exciting chemical, called NMDA, caused an invasion of the brain's immune cells, called microglia, and an increase in AEA levels. Importantly, they found that adding AEA to such damaged brain tissue abolished inflammatory dam...

Landmark discovery of a Kaposi's sarcoma-associated herpesvirus receptor

...s own infectivity and dissemination in the body by inducing a physiological state that results in increased numbers of its own receptor. "The advancement of knowledge achieved in this study highlights the outstanding intramural research that takes place here on the NIH campus," says Elias A. Zerhouni, M.D., ...

MIT researchers build tiny batteries with viruses

... assemble them where they belong. A new means of inducing this order comes from self-assembly, a tool that is commonly used now in Hammond's lab. "By harnessing the electrostatic nature of the assembly process with the functional properties of the virus, we can create highly ordered composite thin films com...

Marrow-derived stem cells deliver new cytokine to kill brain tumor cells, offer protection

...IL-12, and tumor necrosis factor related apoptosis inducing ligand (TRAIL). "Each cytokine has unique functions. What we want to do is marry the function with the therapeutic response we want to achieve. Interleukin-23 promotes the function of dendritic cells and memory T-cells, important components in an im...

First direct mechanical communication of mitochondria, cardiomyocyte nucleus shown

...hypothesize that drugs or intracellular conditions inducing mitochrondrial swelling could by mechanical means influence gene expression. "More studies are needed to explore this very intriguing and promising field of knowledge," he concluded. In the experiment, the researchers found that in an artificial ...

Researchers find molecular 'brake' to cell death

...cell death, so many anti-cancer therapies focus on inducing apoptosis in these cells, Tang says. But the notion of how to push cancer cells to die has been flawed, Tang says. These new findings "overturn a scientific dogma so long accepted that it has become a textbook standard when talking about apoptosis,"...

Septum keeps neurons in synch, can reduce epileptic seizures by 90 percent

...brain's septum helps prevent epileptic seizures by inducing rhythmical electrical activity in the circuits of ... is looking for a new treatment that will focus on inducing theta. "The understanding of the theta rhythm's anti-epileptic effect at the cellular and molecular...

Viral hitchhiker inhibits Wolbachia bacteria's ability to proliferate

...til now, scientists believed the virus was somehow inducing this process. But viruses pirate cells to reproduce, often killing the cells as a result. So Bordenstein and his colleagues hypothesized that by preying on Wolbachia cells, the WO-B virus might reduce the incidence of cytoplasmic incompatibility in ...

Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

...y, especially when combined with chemotherapy. By inducing cell suicide (apoptosis) among blood vessel cells, the treatment steeply reduced the number of small blood vessels feeding the tumor, cut the percentage of proliferating tumor cells and increased cell suicide among cancer cells. Sood and Profes...

Robots manipulating animal behaviour

...rs. Firstly, by changing the way animals behave or inducing collective behaviour, scientists can learn much about animal communications and information processing. Secondly, the ability to create 'mixed systems', where artificial agents interact with natural ones, is a long-held dream for many in the scientif...

Study challenges myth that sex late in pregnancy hastens birth

... suggests that sexual intercourse has no effect on inducing labor, Schaffir said. He acknowledged that women who are more comfortable late in pregnancy may be more likely to engage in sexual activity, and that women who experience abdominal discomfort or pelvic pressure ?possible signs of earlier delivery ?w...

Killing brain tumors from within: A 'Trojan horse' approach

...ethod for targeting malignant brain tumors through inducing the cancerous cells to "commit suicide" has been developed by a team of researchers headed by a Hebrew University of Jerusalem professor of biochemistry. Alexander Levitzki, who is the Wolfson Family Professor of Biochemistry, his research associ...

New neurons could act to alleviate epilepsy

...sults suggest that therapies for epilepsy aimed at inducing neurogenesis could prove effective in alleviating the disorder. In an article in the December 21, 2006, issue of the journal Neuron, published by Cell Press, Olle Lindvall and colleagues at Lund University Hospital and Stem Cell Center described stu...

Therapeutic role found for carbon monoxide

...ing growth of the vessels' smooth muscle cells and inducing apoptosis, or cell death," he adds. Consequently, as the smooth muscle cells died, both the pulmonary blood vessels and right heart were restored to their normal size, what Otterbein describes as a case of "retro-remodeling." "However, what we found...

Pleasure and pain: Study shows brain's 'pleasure chemical' is involved in response to pain too

...d brain-scanning and a carefully controlled way of inducing muscle pain, the researchers show that the brain's dopamine system is highly active while someone experiences pain ?and that this response varies between individuals in a way that relates directly to how the pain makes them feel. It's the first time ...

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