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Tag: "induced" at biology news

U of M researcher examines newly emerging deadly disease

...se patients resulted from massive cytokine release induced by the S. aureus strains. ...

Gene Therapy For Parkinson's Disease Moves Forward In Animals

...t part of the brain called the striatum. They then induced Parkinson-like conditions by introducing a drug to destroy the dopamine-producing cells. Seventeen weeks after that, not only did the GDNF-treated monkeys show improvement in performing tasks, analysis of brain tissue showed the animals' dopamine sys...

The Bacteria's guide to survival

.... Also, a majority of these genes were known to be induced by a family of proteins called mitogen-activated protein kinases, or MAPKs. The researchers showed that blocking MAPKs reduced the activity of several of the genes that are usually enhanced by infection with the normal bacteria. Also, they found that...

Scientists discover how fish evolved to float at different sea depths

...m by 100 million years. The special blood proteins induced development of the swimbladder system. Dr Berenbrink continued: "Many researchers believe that the swimbladder evolved from a primitive lung, which can be traced back 400 million years. These findings will help us to understand the diversity and suc...

Gene therapy for Parkinson's disease moves forward in animals

...t part of the brain called the striatum. They then induced Parkinson-like conditions by introducing a drug to destroy the dopamine-producing cells. Seventeen weeks after that, not only did the GDNF-treated monkeys show improvement in performing tasks, analysis of brain tissue showed the animals' dopamine sys...

Special Imaging Study Shows Failing Hearts Are 'Energy Starved'

... cardiac CK flux at rest and with pharmaceutically induced stress to determine whether increased energy demand during stress increases the rate of ATP synthesis through CK. Then, 17 patients with histories of heart failure were similarly tested to measure the CK flux. Results showed that CK flux in healthy...

Pathogen-Mimicking Vaccine As Strategy For Cancer Therapy

...) from a melanoma antigen known as Melan-A/MART-1, induced CD8+ T cells that specifically recognized cells displaying Melan-A/MART-1 on their surface. This T cell response occurred in all eight patients in the trial. Responses were one order of magnitude higher than those observed in eight patients who recei...

Buying Time Through Hibernation on Demand

...n Cancer Research Center have, for the first time, induced a state of reversible metabolic hibernation in mic...scientist in Roth's lab. Clinical applications of induced metabolic hibernation could include treating severe blood-loss injury, hypothermia, malignant fever,...

U-M team recovers ancient whale in Egyptian desert

...n Cancer Research Center have, for the first time, induced a state of reversible metabolic hibernation in mic...scientist in Roth's lab. Clinical applications of induced metabolic hibernation could include treating severe blood-loss injury, hypothermia, malignant fever,...

Brain-mapping technique aids understanding of sleep, wakefulness

... you tend to stay awake, a process called activity induced consolidation of wakefulness. Some neurons in the basal forebrain produce the chemical acetylcholine. These cells are very active during wakefulness when an animal or human is aroused and attentive. Previous studies have shown that orexin neurons pr...

UNC launches study of liver injury caused by drugs

... insight into medical problems beyond liver injury induced by drugs, he added. "Drug-induced liver injury is an ideal model to study how genes and environment interact to produce disease in some but not all people. We hope the factors identified by DILIN research will provide clues to susceptibility to the ...

NYU and MSKCC research provides model for understanding chemically induced cancer initiation

...ons for understanding the initiation of chemically induced cancers. The findings appear as the cover story in the latest issue of the Journal of Molecular Biology. This team was headed by Dinshaw Patel at MSKCC, Nicholas Geacintov, chair of NYU's chemistry department, and Suse Broyde, a professor in NYU's b...

Oceans more vulnerable to agricultural runoff than previously thought, study finds

... zones According to the researchers, artificially induced algal blooms could have major impacts on recreational and commercial fishing, major industries in the gulf. Red tides, for example, can cause outbreaks of life-threatening diseases, such as paralytic shellfish poisoning, which can shut down mussel an...

Protein prevents detrimental immune effects of bacterial sepsis

...rmal mice were treated with LPS, the immune system induced a steady migration of white blood cells from the blood into affected tissues. However, mice deficient for annexin 1 exhibited a dramatic release of white blood cells from blood vessels, ultimately leading to 100% mortality by 48 hours. The researche...

Findings have implications for tracking disease, drugs at the molecular level

... particles comparable in size to a molecule can be induced to emit light so strongly that it is readily possi...ht using a technique called multiphoton absorption induced luminescence (MAIL). The most efficient gold nanoparticles could be observed at laser intensities l...

Young Blood Revives Aging Muscles, Stanford Researchers Find

...ed the two mice to share a blood supply. They then induced muscle damage only in the older mice. Bathed in the presence of younger blood, the old muscles healed normally. In contrast, when old mice were connected to other old mice they healed slowly. In similar work, the group examined the livers of older m...

Chemical Engineer Kao Explores Antibiotic Synthesis With DNA Chips

...to new positions anywhere in the genome. Mutations induced by transposons are significantly easier to identify. A technique called DNA shuffling, recently developed by the Redwood City-based company Maxygen, provides Kao with a second advantage--speed. After one round of generating mutants with transposons,...

Natural Killers Could Lead to New Hepatitis Treatments

...g, as well as a decreased severity of artificially induced hepatitis. “So, all the evidence we can obtain so far points to CXCR6 being involved in promoting survival of these NKT cells when they get into the environment of the liver, and that's how the cells tend to accumulate there,?said Littman. “Our data...

Researchers Closer To Helping Hearing-Impaired Using Stem Cells

...ously shown that the marrow stromal cells could be induced to transform into neuronal cells, but it wasn’t clear whether, or how, the cells could be further transformed into useful specialized neurons. In a two-step process, Dr. Hashino and her colleagues first cultivated mouse marrow stromal cells with che...

New vaccine means bye-bye to bacteria in the lung

...the vector. Immunization of mice with this vaccine induced antibody production and protected the mice from exposure to a deadly dose of the bacteria. Importantly, the mice could be repeatedly given the vaccine and the immune response against P. aeruginosa was boosted. Usually, adenovirus vectors do not allow...

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