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Tag: "induce" at biology news

Mechanisms involved with tumor relapse identified

... relapse, we can create tailored vaccines that can induce specific types of immune responses in patients, ra...esponses - some of which may be detrimental or may induce tumor relapse," said lead investigator, Masoud H. Manjili, D.V.M., Ph.D., a member scientist with th...

Liver regeneration may be simpler than previously thought

... a developing embryo. Many of the proteins that induce organ regeneration have been identified and scientists are now trying to make organs regrow by stimulating these proteins. Regrowing livers this way would be especially useful for patients whose livers are so damaged ?say, by a tumor that has spread ...

In-shell vaccine for chick disease

...Compton, explained, "This hybrid virus was able to induce immunity when inoculated before hatching. When hatched chicks were exposed to the virulent M41 strain, we observed protection rates of up to 100 percent. With the UK poultry industry sustaining losses of £23.6M a year to infectious bronchitis virus w...

Genetic pathways to curable and incurable forms of pancreatic cancer identified

...rently to a key signaling protein, TGFb, which can induce cancer cells to change shape and become more mobile and invasive. It turns out that the cystic pancreatic cancer cells are resistant to these effects of TGFb and these types of cancers are also less likely to invade surrounding tissues and to metasta...

Anthrax attack posed greater potential threat than thought

...ot appear to trigger an antibody response, but did induce a response by cells of the immune system, Intermediate exposure induced both. Finally, cellular immune responses declined with post-exposure use of antibiotics, suggesting that the intervention impeded spore germination and implying that it may reduc...

Africa's first large-scale HIV vaccine study launches

..."It will determine the usefulness of vaccines that induce high immune response to the parts of the virus that are similar between different strains of HIV-1." The study is known as a phase IIb or "test of concept" efficacy trial because it enables researchers to determine whether the test vaccine prevents...

Major gene study uncovers secrets of leukemia

...ese genes coordinate the complex changes needed to induce progenitor cells to differentiate into B lymphocytes. In ALL, the leukemic cells fail to differentiate normally and instead remain blocked at an immature stage of development. Locked in this state, the leukemic cells continue to proliferate, and this...

Studies force new view on biology of flavonoids

...ue in cancer prevention. "Flavonoids could also induce mechanisms that help kill cancer cells and inhibit tumor invasion," Frei added. It also appears that flavonoids increase the activation of existing nitric oxide synthase, which has the effect of keeping blood vessels healthy and relaxed, preventin...

It's never too late to get it back! Aging interrupted

...at reducing calorie intake later in life can still induce many of the health and longevity benefits of life-long calorie reduction. Importantly, this also includes anti-cancer effects. They are using this knowledge to establish a novel screening technique to find drugs which mimic this longevity effect. “...

Researchers wake up viruses inside tumors to image and then destroy cancers

...an array of new, as well as older agents, that can induce lytic infection, and a particular agent could be tailored for use in a specific patient through imaging," he says. ...

Biodegradable microspheres deliver time release vaccines, stimulate different immune response

...itic cells, we can start tailoring our vaccines to induce a better cellular response. If we can tailor the immune response, it holds greater promise for vaccines that we do not currently have," says Wilson-Welder. ...

Iowa State scientists demonstrate first use of nanotechnology to enter plant cells

...same time," Wang said. "We can bring in a gene and induce it in a controlled manner at the same time and at the same location. That’s never been done before." The controlled release will improve the ability to study gene function in plants. And in the future, scientists could use the new technology to de...

Implanting dopamine generators in brain cells obtains improvement in Parkinson's in monkeys

...cells to release substances (trophic factors) that induce an increase of the dopaminergic cells (that usually exist in the normal brain but in lower quantities). Amongst these trophic factors is the GNDF (Glial Cell-derived Neurotrophic Factor). Cells extracted from the carotid body have been used as a s...

The quest for an effective HIV vaccine presents new possibilities, challenges

... if these so-called T-cell vaccines that primarily induce a cellular immune response can have a beneficial e...irus is never completely eliminated. Vaccines that induce strong cellular immune responses may have some benefits, say the authors. In non-human primate model...

Chemical maps hint at drug's effects on schizophrenia

...s than the older antipsychotics, but several still induce weight gain and diabetes. Schizophrenic patients were found to have lower levels of the lipids used to make membranes involved in storing and communicating information in the brain. These lipid changes were partially reversed in patients treated w...

Slowing the racing heart

...-- the pacemaker cell -- beats faster or slower to induce a rhythmic heartbeat that varies to increase or decrease the blood flow to the body as we eat, sleep or exercise. "Disturbances of pacemaker control are common in heart diseases. When the heartbeat becomes non-rhythmic and chaotic, it can result ...

Fat screen delivers plant-derived chemical with antidiabetic effects

...California, Los Angeles. Harmine has been known to induce hallucinations, convulsions, and tremors. The principal class of drugs prescribed for obesity-related diabetes, called thiazolidinediones or TZDs, work through a counterintuitive mechanism: they restore insulin sensitivity by activating a central ...

Newborn neurons like to hang with the 'in' crowd

... signaling molecules travel across the synapse and induce a signal on the neighboring, receiving nerve fiber or dendrite. A typical neuron sports about 7,000 synapses through which it stays in touch with roughly 1,000 other cells. But just how young neurons make their presence known and hook up with already...

Scripps research team sheds light on long-sought cold sensation gene

...ight one day lead to the development of drugs that induce cold sensation as an analgesic, or block it to prevent certain forms of chronic pain associated with cold sensation. "This study represents the first demonstration that a single gene is responsible for most cool temperature sensation," says team lea...

New study suggests potential for a broadly-protective HIV vaccine

...cent.shtml . To be effective, an HIV vaccine must induce the body to produce cross-reactive antibodies that can neutralize multiple strains. USU Professors CAPT Gerald Quinnan, Jr., M.D., USPHS, and Christopher Broder, Ph.D., and their colleagues at USU attempted to elicit these broad-range antibodies in a...

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