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Tag: "induce" at biology news

Proteins spur diabetic mice models to grow blood vessels, nerves

... four major classes of neural guidance cues, which induce axons or nerve fibers to extend in specific directions during development. In 2004, Li and his colleagues showed in laboratory cultures that in addition to promoting nerve growth, Netrin-1 also induced formation of blood vessels. ...

Discovery may speed forest biotechnology

...pplied research, Strauss said, researchers can now induce activation of the FT gene earlier, so that trees will reproduce at much younger ages ?months instead of years - and better lend themselves to conventional genetic manipulation. It could be possible, he said, to more rapidly breed some desirable trait...

UC San Diego biologists solve plant growth hormone enigma

...." Applying auxin to the flowers by hand can also induce seedless tomatoes, or other seedless fruit, but this method is too tedious to be useful for commercial purposes. Seedless fruits would not just be novelty items. For example, Zhao points out that seeds significantly increase the effort and waste in...

Malignant melanoma cells secrete protein required for embryo formation

...ell-derived signals, and were consequently able to induce ectopic (abnormal) embryonic skull and backbone (axes) formation. "This finding highlights the convergence of tumorigenic and embryonic signaling pathways. From a translational perspective, Nodal signaling provides a novel target for treatment of a...

New pathways for autoimmune treatment identified

...enior author. "If you are killing too hard, it can induce autoimmune disease. If you regulate suppression too hard, you can get cancer. i NKT cells help maintain a healthy balance. But patients with autoimmune disease may not have enough functional iNKT cells." "Aire controls the development and function...

Researchers map out networks that determine cell fate

...progenitor-like state," said Singh. "If you could induce them to resolve that state ¡X to differentiate into one or the other cell type ¡X they would cease to be tumorigenic." ...

First human study confirms that immune cells can be a primary cause of bone loss in gum disease

...l tissues were functionally sufficiently potent to induce bone destructive cells (osteoclasts) in a laboratory culture system, in spite of the elevated presence of B and T lymphocytes. Since it has never been reported that any bacteria per se invade and resorb bone independent of osteoclast activation, RANK...

For Stanford scientists, RNAi gene therapy takes two steps forward, one step back

...reports had suggested that RNAi gene therapy might induce an immune reaction or switch off the wrong gene or genes. As these concerns faded, things began looking up for RNAi with three RNAi therapies now in human trials - two for macular degeneration and one for a type of pneumonia. However, these studies ...

Microscopic passengers to hitch ride on space shuttle

...pcoming mission. "Spaceflight has been shown to induce key changes in both human and microbial cells that are directly relevant to infectious disease, including changes in immune system function, microbial growth rates, antibiotic resistance, and cell surface properties," explained Nickerson. "It is exc...

Septum keeps neurons in synch, can reduce epileptic seizures by 90 percent

...ericans, he said. There are a variety of ways to induce neurons to fire rhythmically, including, interestingly, engaging in stimulating cognitive activities. Scientists and medical providers know that brain lesions, skull fractures, and high fever are among the factors that can produce epilepsy. But in m...

Research reveals inner workings of immune system 'thermostat'

...ammation, which, if unchecked, can destroy tissue, induce shock and kill the host. So immune system cells le...other," Yap said. "Here we show that they actually induce each other. 'Hot' cytokines don't inhibit 'cool' ones ?they trigger their production. Wounding, in e...

Heart has enough oxygen to survive hypothermia, CPR crucial

...o use hypothermia to reduce oxygen consumption, to induce cardiac standstill and to restart the heart by rewarming, Tveita noted. But research on hypothermia dropped off markedly after the surgical application was established. However, deaths from accidental hypothermia continue, and not just in the colde...

New egg freezing technique offers hope to hundreds of women

...ignificant and I deduced that cryopreservation may induce irreversible damage to the bonding of the microtubules," she said. Professor Nottola, an associate professor of anatomy in the Department of Anatomy, University La Sapienza, Rome, Italy, told the conference that a variety of abnormalities became app...

Protein-coated dental implants could improve bone regeneration

Titanium dental implants coated with proteins that induce bone formation may be a key advancement in treating tooth loss due to gum disease, researchers say. In laboratory tests, MCG researchers applied a protein onto implants that directs endogenous stem cells to become bone-forming cells. The result was...

Study details hepatitis C ability to block immune system response

... persist. "Our new work shows that HCV does not induce interferon-? or antiviral interferon stimulated genes in the infected cells," Chisari said. "This means that the antiviral interferon stimulated genes expressed in the HCV-infected liver are likely produced by uninfected cells in some novel fashion a...

Researcher gives hard thoughts on soft inheritance

...t has to be determined whether the environment can induce an epigenetic change in an organism that can be inherited in subsequent generations. Certainly, nobody has shown that an epigenetically induced beneficial or adaptive change has been inherited. Mechanistically, there is no reason to discount epigene...

Hopkins scientists show hallucinogen in mushrooms creates universal 'mystical' experience

...wn that the active agent in "sacred mushrooms" can induce mystical/spiritual experiences descriptively identical to spontaneous ones people have reported for centuries. The resulting experiences apparently prompt positive changes in behavior and attitude that last several months, at least. The agent, ...

A single sugar found responsible for an antibody's ability to treat inflammation

.... Antibody subclasses have different abilities to induce inflammation in the body by virtue of their selective ability to engage either activating or inhibitory Fc receptors. Earlier work had shown that IVIG infusion changed this ratio of activating and inhibitory receptors on the cells that trigger inflam...

Origen publishes in Nature a robust and versatile method for creating transgenic chickens

... under certain conditions, Origen scientists could induce the PGCs in vitro to differentiate into embryonic germ cells that contribute to somatic tissue. "As well as the practical applications of this work, the ability to engineer PGCs and influence them to commit in cell culture to either the germline or ...

OHSU study says stem cell 'fusion' occurs in tumors

...ink to the charbroiled hamburger you eat, that can induce mutations in the cells. The gut protects itself by rapidly turning over its epithelial cells. Plus, when there is damage to the surface lining, it is critical that regeneration and reestablishment of the barrier occurs rapidly. We think that cell fus...

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