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Tag: "induce" at biology news

Protease inhibitors reach beyond HIV

...cted T cells in vitro, but have also been shown to induce programmed cell death at higher concentrations. The mechanisms for these paradoxical data are unclear, as is whether PI therapy would aid CD4 T cell reconstitution in HIV patients in vivo. In a study appearing online on June 2 in advance of the prin...

Stolen gene allows insect virus to enter cells

...y their insect hosts in a matter of days but don't induce so much as a sneeze in mammals, as potential pesticides. But the viruses would require tweaking to be effective since they kill insects more slowly than chemical insecticides. Studying baculoviruses also yields insights into general viral behavior. T...

Out of sight, out of mind? Not necessarily

... demonstrates that TMS can be used successfully to induce blindsight in people with normal vision. Ro's co-authors on the PNAS paper were graduate student Jennifer Boyer and Stephanie Harrison, a summer intern. ...

US/African project deciphers deadly parasite genome

...ers. "This parasite has an astonishing ability to induce cancer in its host cell in a way that is reversible," says Nene. "There are clear links to cancer biology in humans, and this study has given us some clues to pursue." The genome is also helping scientists who study human malaria, which is carried b...

Research team receives $7.5 million to study cassava

...ntially toxic levels of cyanogens ?substances that induce poisonous cyanide production. "In Africa , improperly processed cassava is a major problem," Sayre said. "It's associated with a number of cyanide-related health disorders, particularly among people who are already malnourished." Sayre's laboratory...

New factor implicated in allergy and asthma attacks

...rect evidence that oxidative stress is required to induce a robust inflammation, and the first demonstration that a source of that stress is right there in the pollen itself," said UTMB associate professor Istvan Boldogh, a lead author of a paper on the research that will be published online August 1 in the...

Fresh water affected by salt from deicing roads

...hloride concentrations were already high enough to induce mortality in aquatic animals and alter wetland plant composition. During the winter months chloride in urbanized areas can increase in waterways to as high as 5 g/l which is equivalent to 25% of seawater concentrations. Dr. Kaushal of the U...

Scientists develop fungus-fighting vaccine

... and that the fungus needs to grow and survive. To induce a robust immune response to the vaccine, the group attached the relatively innocuous beta-glucan to a protein called diptheria toxin that is known to stimulate the immune system and has been used in other human vaccines. The vaccine protected rodent...

Reducing antibiotic use lowers rates of drug-resistant bacteria

...rdered, the dose and duration of antibiotics, "can induce significant and rapid reductions" of penicillin-resistant pneumococcal colonization in areas that have high rates of drug-resistant bacteria, according to the study. In essence, doctors can make their own jobs easier by prescribing antibiotics more j...

Prostate cancer uses Wnt signaling proteins to promote growth of bone tumors

...Our hypothesis is that prostate cancer cells first induce more bone resorption to help the invading cells become established in bone. But then there's a switch to increased bone production. Although we don't know the exact mechanism responsible for the switch, we know that it's related to the activity of Wn...

Model identifies genes that induce normal skin cells to become abnormal

...icroenvironment of metastatic melanoma cells could induce benign skin cells to become cancer-like. The researchers seeded a particularly aggressive form of human metastatic melanoma cells onto a three-dimensional collagen matrix and allowed the cells to precondition the microenvironment for several days. ...

Clinical trial to test stem cell approach for children with brain injury

...ferentiate into new neurons and support cells, and induce brain repair. "This would be an absolutely novel treatment, the first ever with potential to repair a traumatically damaged brain," said James Baumgartner, M.D., associate professor of pediatric neurosurgery and co-principal investigator on the pr...

Synthetic Protein Eases Arthritis Symptoms in Mice

...f techniques (including injection of TNF-alpha) to induce arthritis symptoms in mice. Researchers also injected some of the animals with lab-made PLAD (P60 PLAD). “We found that P60 PLAD protein powerfully inhibited the symptoms of TNF-alpha-induced arthritis,?says Dr. Lenardo. P60 PLAD also lessened the ef...

Limiting the damage in stroke

...vantage of this system is that we can specifically induce or block this signaling pathway at virtually any time and selectively in neurons," Wirth emphasizes. Putting all of this expertise together permitted the researchers to get a clear picture of IKK2's role after a stroke. Mice with the hyperactive fo...

Sahara's edge studied from ground, air and space to improve water management

...pressure to put remaining supplies out of reach or induce contamination from nearby saline water deposits. Working with partners including African water agencies, ESA has commenced a project called Aquifer to develop satellite-derived products and services to support the sustainable management of ground w...

UCLA discovery will aid in treatment of patients with a deadly brain cancer

...t disease, but the idea that it may be possible to induce long-term disease suppression gives us reason for hope." The study, Mischel said, also may have important implications in other cancers. "Many cancers have a similar combination of a mutant cancer-causing protein and either the expression or loss ...

Scientists show how thinking can harm brain cells

... propose a strategy of chemical preconditioning to induce adaptations in nerve cells that would enable the c...h small amounts could trigger protective genes and induce adaptations that will make the dendrites more able to withstand insults," Bellizzi said. Diazoxide ...

Human trial proves ricin vaccine safe, induces neutralizing antibodies; further tests planned

...in and genetically engineered it to be safe and to induce protective immunity in humans." Dr. Vitetta's work with ricin received international attention when she and a team of UT Southwestern researchers in the Cancer Immunobiology Center developed the experimental vaccine for the deadly toxin as an outgro...

H5N1 avian flu virus vaccine induces immune responses in healthy adults

...f an experimental H5N1 avian influenza vaccine can induce immune responses in healthy adults. Approximately half of those volunteers who received an initial and a booster dose of the highest dosage of the vaccine tested in the trial developed levels of infection-fighting antibodies that current tests pred...

Ocean 'dead zones' trigger sex changes in fish, posing extinction threat

...ls of dissolved oxygen, also known as hypoxia, can induce sex changes in embryonic fish, leading to an overabundance of males. As these predominately male fish mature, it is unlikely they will be able to reproduce in sufficient numbers to maintain sustainable populations, Wu says. Low oxygen levels also mig...

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