Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism
...patients with coronary artery disease, are able to induce the activation not only of genes involved in apopt...urified from patients with coronary artery disease induce endothelial cells damage and support the hypothesis that virus infection plays a crucial role in med...How 'memory' T cells curb the spread of viruses throughout the body
...om recurrence of the disease. Similarly, vaccines induce the production of memory lymphocytes, but without causing disease. While scientists have long known the role of antibodies in protection, whether memory cells, known as CD8 T cells, could prevent viral diseases has been debated. The new work by Fo...Microbes at work cleaning up the environment
.... They also studied whether various amino acids induce rapid aggregation in metal-sulfide nanoparticles. The answer was yes in both cases. “This demonstrates an extracellular biomineralization mechanism that is unexpected because it involves the bacteria excreting proteins for nanoparticle aggrega...Progress toward an antitumor vaccine
How can we induce the body to use its own weapon, the immune system, to battle cancer" In principle, by the same means used against infectious diseases: immunization. The production of a selective vaccine is not a trivial task, however. A team led by Horst Kunst at th...Study shows lizard moms dress their children for success
...ound that female side-blotched lizards are able to induce different color patterns in their offspring in response to social cues, "dressing" their progeny in patterns they will wear for the rest of their lives. The mother's influence gives her progeny the patterns most likely to ensure success under the con...Researchers shed light on mechanism of action used by anti-cancer drug
...tein loads. The net effect of these actions was to induce a shutdown of protein synthesis accompanied by a dramatic increase in cell death. “The notion that sorafenib acts by inhibiting protein synthesis and reducing expression of Mcl-1 suggests that this agent might be logically combined with other tar...Studies to find better ways to preserve human eggs, ovarian tissue under way
...has breast cancer, for example, hormones needed to induce ovulation could be problematic because many breast cancer cells have estrogen receptors. As pieces of a puzzle come together, Dr. Song notes scientists already are developing methods to stimulate ovarian tissue to produce eggs outside the body, a ...The insect vector always bites twice
...s, including immunogenic ones that can modulate or induce a human immune response. Working for the EpiVect programme initiated in 2003 (1), scientists from IRD research unit UR 024 studied this still little known response with the aim of identifying in the arthropod vector saliva the immunogenic proteins re...Simulations unravel outer membrane transport mechanism
...an order of magnitude higher than that required to induce the unfolding. This clearly indicates that the unplugging mechanism is very unlikely.” Coupled with increasingly sophisticated crystallographic studies and basic biological data, simulations help researchers study the interactions of multiple prot...Research identifies protein that signals flowering in squash plants
...tems, where it acts together with other factors to induce flowering. The precise nature of the florigenic signal has eluded plant biologists for over 70 years, owing to the difficulties attendant with the accurate detection and measurement of compounds in phloem sap, and designing experiments to allow accur...