Cardiologist's 'living chip' changes science of disease monitoring
...industry. The concept has seen strong support from individuals such as Terry Gronwall, an entrepreneur-in-residence at the High Tech Rochester Incubator, who took the lead in assessing Physiologic Communication's success potential and mentoring the researchers in the complicated art of business. All the resour...Gene therapy for hereditary lung disease advances
...uthorities suspect less than 5 percent of affected individuals are diagnosed, often not until they are in their mid- to late-30s, after extensive lung damage occurs. Shortness of breath, wheezing, chronic cough and recurring chest colds are signs of the disease. It is important that alpha-1 patients avoid cig...New technology used to construct the first map of structural variation in the human genome
...t for a large amount of phenotypic variation among individuals and ethnic populations, including differential res...(CGH), which involves tagging genomic DNA from two individuals and then co-hybridizing it to the array. Data from the array were assessed with a new algorithmic t...Tuberculosis: The bacillus takes refuge in adipose cells
... to eradicate the bacillus entirely from infected individuals should take these newly identified reservoir cells into account. Mycobacterium tuberculosis, the bacillus responsible for tuberculosis can hide, in a dormant state, in adipose cells throughout the body. The bacterium is protected in this cellular en...Buildup of damaged DNA in cells drives aging
...ogeria, a rare inherited disease in which affected individuals age rapidly and die prematurely. "These progeroid mice, even though they do not live very long, have remarkably similar characteristics to normal old mice, from their physical symptoms, to their metabolic and hormonal changes and pathology, right do......different messages, and our data show that distant individuals are able to distinguish between different song types and understand what they mean. This study offers the first evidence of a functionally referential communication system in a free-ranging ape species." "Finding this ability among ape species, es...Age-related changes in DNA repair illuminate the connection between age and genetic damage
...risky methods of DNA repair used by cells of young individuals contribute to the accumulation of genetic damage, and perhaps to the aging process itself. Older cells may use the safer repair methods, but they still carry the genetic damage incurred during DNA repair in the fly's "reckless" youth. ...Wolves are suffering less from inbreeding than expected
...show that it is the most genetically variable wolf individuals that are recruited into the breeding population. A...980 and a single male ten years later. With so few individuals founding the population the level of inbreeding is high. By the use of DNA-analyses the research tea...Mayo Clinic study suggests that a central nervous system viral infection can lead to memory deficits
... one billion people worldwide each year. Generally individuals contract two or three enterovirus and/or rhinovirus infections each year. In some cases the viruses get into the brain, and in some children these viruses can cause long-lasting brain injuries. "We think picornavirus family members cross into the bra...Researchers make progress in studying genetic traits of India-born populations
...gan, have conducted genetic analysis of India-born individuals in the U.S. Through their studies, they have begun...1,200 genome-wide polymorphisms collected from 432 individuals representing 15 different Indian populations. This study represents the largest study of Indian ...International team analyzes human genetic variation in key immune region
...c diversity that exists in the MHC among different individuals and the tendency for multiple genetic differences ...e variability in its DNA sequence in more than 350 individuals from diverse geographic regions, including Africa, Europe, China and Japan. Specifically, the resear...A human taste for rarity spells disaster for endangered species
...ish a species because the cost of finding the last individuals would outweigh the benefits. But a new theoretical...ological process called the Allee effect, in which individuals of many plant and animal species suffer reduced fitness at low population densities, which increases...Female pronghorns choose mate based on substance as well as show
... Idaho, obtained genetic markers for all pronghorn individuals in the population and assigned paternity to the offspring. "The females' mate sampling creates a small group of males that each year sire more than one-half of all young," said Byers, who is currently serving as a program officer in NSF's biologica...Gene therapy study takes aim at prostate cancer
...atients qualified to participate in this study are individuals diagnosed with high grade prostate cancer (Gleason grade 7 or higher), or who have a blood PSA level of 10ng/ml or higher and are contemplating surgery (radical prostatectomy). To register for the study or to obtain further information, patients may ...When nerve cells can't make contact
...ease is accompanied by mental disability. Autistic individuals exhibiting high intelligence or outstanding skills in a particular area, called "savants", such as the main character in the film "Rain Man", are rare. Even up to the middle of the last century, exceptionally cold emotional behaviour on the part of...Mother birds give a nutritional leg up to chicks with unattractive fathers
... success. "For house finches, a species in which individuals are short-lived [and] present a high risk of death, a focus on the immediate reproductive attempts may be the only viable strategy," write the researchers. "By depositing antioxidants in a compensatory manner, females can maximize the reproductive ou...Scientists work to identify genes that contribute to early heart attack risk
...y looking for genetic variants that may predispose individuals to develop early atherosclerosis. "Perhaps the most remarkable thing about this study is the large number of genetic variants that we’re going to study," said Herrington. "Using special technology provided by Perlegen Sciences, we will examine mor...Looking to a new era in bee research
... those studying mammals and humans. A total of 112 individuals in 63 institutions around the world signed on to analyse the newly available honey bee genome sequence, generating exciting results in many areas of biology. Themes for analysis included Anti-Xenobiotic Defence Mechanisms, Bee Disease and Immunit...Jefferson scientists identify gene mutation potentially involved in breast cancer initiation
...h more likely to have a cancer recur than are such individuals who don't carry caveolin gene mutations. "It's a risk factor," he notes. ...Tests for 'face-blindness' reveal disorder may not be so rare
...'s Faculty of Arts and Sciences. "Testing of 1,600 individuals found that 2 percent of the general public may hav...e they cannot keep track of characters. Face-blind individuals often compensate for their prosopagnosia using non-facial traits, such as hair, gait, clothing, voic...