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Tag: "indication" at biology news

Wisconsin scientists discover a master key to microbes' pathogenic lifestyles

...and geographically widespread class of fungi is an indication that it was acquired from a common ancestor deep in evolutionary history. The feature is a common mechanism used by the different organisms to adapt to a new environment: the lungs of animals. "It is a story of how organisms are challenged in a new ...

HIV accessory protein disables host immunity via receptor-protein intermediary

...ice are immune to toxins created by pathogens ?one indication that their immune surveillance has been compromised. Using biochemistry tests, the researchers were able to show that Vpr does interact with PARP-1 through the glucocorticoid receptor. Vpr hitches a ride on the glucocorticoid receptor, driving glu...

Researchers quantify more noise in gene expression

...rch to the beat of subtly different phenotypes, an indication of heterogeneity which led bioengineering researchers at the University of California, San Diego (UCSD) to devised computer algorithms that identify the underlying sources of variation at the basic level of life: unscripted fluctuations within indivi...

Gene controls whether fear is a factor

...ditions that have previously proven unpleasant, an indication that the mice lack a normal memory for fear. "Whi...inued to perform normally on a water maze test, an indication that spatial learning and memory--controlled outside of the amygdala--were unaltered. "The findings...

Study uncovers placental microtransfusions lead to transmission of AIDS virus during childbirth

...h links the placenta to the baby, that would be an indication of mixing, that something tore in the placenta and leaked the mothers' virus-contaminated blood to the infant." Researchers then compared what they found in cord blood to whether or not infants were infected with HIV, he said. "We looked for a stat...

Building a better mouse model of lung cancer: FHIT counts

...ght this was interesting because this is the first indication that loss of just one of the two copies of the VHL gene could contribute to the development of cancer," says Huebner, noting that loss of one copy of the VHL gene occurs in several types of human lung cancer. Huebner says there is still plenty of ro...

Agricultural workers at increased risk for infection with animal flu viruses

... with the control group. Farmers had the strongest indication of exposure to swine flu viruses, as much as 35 times higher than the control group. Similarly, comparable values were as much as 18 times higher for veterinarians and as much as 7 times higher for meat processors than the control group. In contrast,...

Study hints at role of stem cell genes in testicular, breast cancers

...n Embryonic Stem Cell Center. "This is the first indication that these genes are markers of breast cancer. The finding might lead to information about where breast cancers come from," Clark adds. "Are they derived from an original stem cell population, one that is expressing these genes, or do the cells in th...

Scientists closer to new cancer detection method

...d at about 50 nanoseconds." The result is a clear indication of the presence of PDGF. "The problem of backgrou...body fluid or blood and a color change would be an indication of the existence of a cancer biomarker in the body. In that event, the person could seek a more thor...

Baby's genes affect mom's cholesterol levels

...placenta originate from the fetus, they are a good indication of the genes and proteins produced by the baby. Descamps and his co-workers discovered that the baby's genes had almost as much influence as the mother's genes on her lipoprotein levels. Because increased levels of lipoproteins can lead to pre-ecla...

Disappearing arctic lakes linked to climate change

... "The changing lakes are a consistent, measurable indication of the overall changes to hydrology in the Arctic," said Hinzman. "The loss of surface water will inevitably impact local ecosystems, which will have a cascading effect. Changes could include loss of migratory bird habitat resulting in an effect on s...

Neanderthal teeth grew no faster than comparable modern humans'

...ok for the tooth to mature. And that gives them an indication of the length of an individual's childhood. Neanderthals, Homo neanderthalensis, were the dominant hominid inhabiting most of what is now Europe and western Asia . Remains have been found as far south as Iraq and as far north as Great Britain . Fos...

Nanowires can detect molecular signs of cancer, scientists find

...momentary change in conductance that gives a clear indication of the marker's presence. The detectors differentiate among various cancer markers both through the specific receptors used to snag them and because each binds its receptor for a characteristic length of time before dislodging. "Our results show th...

New lead reported in tumor angiogenesis

...t line the walls of the blood vessels, there is no indication that resistance is a problem. It's an intriguing idea, and one that we think might be well worth pursuing." This month's paper, as is often the case in the world of science, involves a great deal of hard work - and a little luck. Wang said his group...

Identification of specific genes predicts which patients will respond to Hepatitis C treatment

...s and/or liver cancer. It is currently the leading indication for liver transplants. Liver biopsies were performed on the 31 chronic HCV patients before treatment, and were compared to 20 biopsies from healthy, uninfected livers. 16 patients did not respond to subsequent treatment, while 15 did; both groups we...

International Team Determines Geographic Origin of Leprosy

...very 28,400 letter pairs. The rarity of SNPs is an indication of extreme genetic stability: all the strains of leprosy throughout the world are essentially identical. The discovery of the four SNP types could help health officials better understand leprosy in present day human populations, says Christine Sizem...

Scientists discover odd-ball rodent

...orried about wildlife loss; but of course it is an indication of how little we know, and a window onto what we could be losing without ever knowing," said Dr. Timmins. ...

Molecular thermometers on skin cells detect heat and camphor

...y receptors that participate in signaling pain--an indication for which there is a great need for new therapeutics. Indeed, several compounds that are currently under investigation for alleviating chronic pain target the action of a protein called TRPV1 (VR1), which is similar to TRPV3. Molecular Thermometers...

Researchers discover underwater volcano

...sting maps of the seafloor in the area gave little indication that this volcano existed. When sound beams were directed into the crater this time, they measured an unusually shallow depth. These interesting results prompted further investigation of the area using the manned submersible Pisces V-a seven-foot sph...

Insight into DNA's 'weakest links' may yield clues to cancer biology

...hromosomes. "The current findings offer the first indication that yeast have fragile sites," said Francene Lemo...d yeast fragile sites may have common features, an indication that a common mechanism may underlie their occurrence, Petes said. Fragile sites in mammalian cells ...

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