Production of key Alzheimer's protein monitored for first time in humans
... However, those fixed assessments of Abeta gave no indication of whether the flood of Abeta in patient's brains came from an increase in the mechanisms that make the protein or a reduction in the processes that regularly clear it from the brain. Because Alzheimer's symptoms take many years to develop, some re...Key to early diagnosis of autism may be in the placenta
...e of any obvious genetic abnormalities would be an indication to have a child examined by a specialist to determine the presence of ASD." ...Pest control research leads to pain control discovery
... withdraw more quickly from a noxious stimulus, an indication of 'hyperalgesia' or heightened response to a painful stimulus. The sEH inhibitors reverse hyperalgesia and bring their withdrawal reaction back into the normal range. Hammock said "these sEHIs are of similar or greater potency in reducing inflamma...Iron critical to ocean productivity, carbon uptake
...viding and growing. But that green color wasn't an indication of health, it was an indication of stress from a lack of iron." The study is also important because it looked at the availability o...Speeding discovery of the 'human cancer genome'
... levels in primary melanomas might also provide an indication of the cancer's likelihood of spreading, although "any prognostic significance would require rigorous investigation and validation in appropriately designed prospective clinical trials." Taking a similar approach, Lowe's team identified two genes ...Protein found to control tumor growth in certain breast cancers
...ally occurring estrogen receptor in vitro, further indication that the protein mediates the sensitivity of hormone-dependent breast cancer cells to tumorigenesis. "While still preliminary, our data adds another critical function to Nod1," Ulevitch said, "namely its ability to regulate the growth of estrogen-se...A large step forward in the fight against African sleeping sickness
...ociated with the disease disappear. There is every indication that this substance can also counteract Trypanosoma brucei rhodesiense in humans − sparing them from African sleeping sickness. ...Most human-chimp differences due to gene regulation ?not genes
...t dramatically, usually in the human lineage -- an indication of powerful incentives to adapt to a changing environment. Of the 1,056 genes from all four species, 60 percent had fairly consistent expression levels across all four species. "The expression levels of these genes seem to have remained constant for...Study reveals classic symbiotic relationship between ants, bacteria
...ties and nourish them with glandular secretions-an indication that the ants, bacteria, fungus and parasites have likely been evolving together for tens of millions of years. "Every ant species [that we have examined] has different, highly modified structures to support different types of bacteria," says Currie...UF scientists trace origin of shark's electric sense
...onstruct vertebrate evolution. It gives us further indication of how all of the various sensory systems come on line." But the idea that the neural crest truly is the source of the electrosensory system will raise eyebrows, scientists say. "It's a very interesting paper for two reasons," said Glenn Northcutt,...Cyclosporine inhibits hepatitis C virus in vitro
...ger follow-up period for that group. Still, the indication that Cyclosporine had novel antiviral properties invites further investigation, the authors write. A prospective randomized comparative trial between cyclosporine and TAC should further evaluate their observations. "Due to the accelerated rate of di...Exotic crab poised for widespread UK invasion
...erienced an major outbreak. This is a fairly good indication that the UK is set for a similar situation." Mitten crabs can be found in the sea or rivers because they are catadromous - meaning they mainly live in freshwater but must migrate to the sea to breed. Their potential for widespread colonisation is i...New mechanism for essential genome-wide gene silencing identified
...d in mammalian cells also, including humans. In an indication of their fundamental nature, critical genetic systems are frequently conserved with few changes in life forms that diverged during evolution millions of years ago. "In our experiments, we saw SUMO binding to histones across the genome, suggesting th...Molecule by molecule, new assay shows real-time gene activity
...kin to a sea of cellular paparazzi -- serves as an indication of that single protein molecule's production. "Dr. Xie's experiments are the first to obtain quantitative, real-time information on protein expression in living cells at the single-molecule level," says Jeremy M. Berg, director of the National Insti...Less is more, gene study shows
...n those who have a working copy. "This is another indication that loss of the gene would be good for the individual, but it doesn't show that the gene became a pseudogene because of that advantage." However, using population genetics techniques, the researchers were able to demonstrate just that. They also det...Cell therapy slows progression of an inherited neurological disease; Improves motor skills in mice
...ld of cell-based therapy and this study is a clear indication of its potential," says Mahendra Rao, MD, PhD, at Johns Hopkins School of Medicine and the Invitrogen Corporation. "This carefully conducted study suggests that a different cell type, such as myelin-producing cells, may be better than others when use...Duck-billed dino crests not linked to sense of smell
...s sense of smell. "From the brain case, there's no indication that the nerves curled upwards into the crest, as we would expect if the crest was used for the sense of smell," Evans says. "It appears that the brain changed very little from their non-crested dinosaur ancestors, and that the primary region of t...A link is found between morphine addiction and the tendency to explore
...ith the effects of this drug, and this gives us an indication of the rat's addiction to the drug. ...Rice bioengineers pioneer techniques for knee repair
...id Athanasiou. "The fact that we can do this is an indication of how far the discipline of tissue engineering has progressed." Unlike cartilage, most tissues in our bodies ?including skin, blood vessels and bone ?regenerate themselves constantly. Tissue engineers try to capitalize on the body's own regenerativ......he last Ice Age. Its decline in recent years is an indication of something changing on the mountain, and we need to find out what it is. He added: "There are also important ecological reasons to save it - for example the squirrel's middens are an important source of food and habitat for chipmunks, voles, and...