Patterns in genome organization may partially explain how microbial cells work
...markers to predetermined spots on chromosomes have indicated that many bacterial genes tend to be found at specific cellular locations. Patterns are not obvious in the sequences of prokaryotic genomes, which led the team led by Palsson to use signal-processing methods to identify long-range spatial patterns in...How does the brain know what the right hand is doing?
...ore the cuff was inflated, the subjects accurately indicated where their hand was pointing, both when they were resting and when they were pushing against the plate. After the arm was paralysed and anaesthetised, the subjects were unable to detect when researchers moved their hand, but incorrectly thought that...Heart-healthy compound in chocolate identified
... of Sciences. "Although previous studies strongly indicated that some flavanol-rich foods, such as wine, tea and cocoa can offer cardiovascular health benefits, we have been able to demonstrate a direct relationship between the intake of certain flavanols present in cocoa, their absorption into the circulatio...Utah researchers confirm chromosome may harbor autism gene
...looked at contained 106 SNPs, 70 of which strongly indicated a gene in that region being linked to autism. One gene, FXR1, appeared to be a likely candidate for a link to autism. FXR1 is similar to the X-chromosome Fragile X gene, FMR1. Mutations in FMR1 cause Fragile X Syndrome, an inherited condition that c...World first research to speed up cure for ear infections
... the results of other gene targeting research have indicated that gene therapy (to target wound healing genes) could prevent wound scarring and be potentially applied to clinical scar treatments. Professor Marcus Atlas, Director of LEHI, said that Dr Ghassemifar's work in LEHI's Tissue Engineering Laboratory ...'Word-vision' brain area confirmed
...nearly as a function of word length. Such findings indicated that the patient had been reduced to recognizing words letter by letter. "How could there be a piece of neural tissue dedicated to a recently invented cognitive skill like word recognition?" wondered Alex Martin in a preview of the paper in the same...Patients now surviving once-fatal immune disease
...eported that they had chronic lung disease, and 33 indicated that they had one or more episodes of sinusitis in the preceding year. Other diseases that were common but not debilitating among this group were arthritis, diarrhea and skin infections. Several factors may have contributed to the increased surviva...Single microRNA causes cancer in transgenic mouse
...es of leukemia and lymphoma, and that its presence indicated a poorer prognosis in patients with breast and lung cancers. Croce, along with Dr. Stefan Costinean , a research associate, decided to isolate miR155 function by inserting the gene, along with an enhancer, to promote its expression, into fertilized...Researchers unravel DNA tangles and enzyme seamstresses
...s of linked and unlinked loops. Their calculations indicated that whether DNA molecules are interlinked is shown by the way they touch each other. Interlinked DNA loops tend to touch in an easily recognizable hook-like way, fitting together perfectly; whereas strands of unlinked DNA molecules tend to curve awa...Intensive statin therapy may partially reverse plaque build-up in arteries
...lesterol lowering treatment. Previous research had indicated that intensive statin therapy could prevent the progression of coronary atherosclerosis, or arterial plaque build-up, but not actually reduce disease burden. ACC.06 is the premier cardiovascular medical meeting, bringing together more than 30,000 car...Face perception is modulated by sexual orientation
...cited responses of similar magnitude. The findings indicated that invariant (facial identity) and variant (faci...aisal of beauty. Rather, the researchers' findings indicated that the orbitofrontal cortex has a more general role in representing the reward value of faces of p...Bone and cartilage growth to blame for heart valve disease
...ance ?totally different than healthy tissue, which indicated to me that the actual structure of the valves had ...urprised when Dr. Rajamannan's unique observations indicated that the process of valve degeneration is instead an active process, linked to inflammation and cell...Chemical signaling helps regulate sensory map formation in the brain
... computational models of this process. His models indicated that at least two counterbalancing signaling systems were required to push and pull the growing and branching axons as they searched for their ultimate topographic positions within the brain. In the 1990s, scientists found the first of those signali...Loosen leash on cancer protein 'watchdog,' researchers say
...mice that had normal p53 activity. The study also indicated that the treated mice did not suffer from the side effect the research team most feared: premature aging, which has been linked to overproduction of p53 in other studies. The discovery could assist in future human cancer treatments. "It's a question...History of human cannibalism eats away at researchers
... to their increased susceptibility to kuru. This indicated that cannibalism conferred an effect of balancing selection on the PRNP gene throughout human history. Bertranpetit and his colleagues sequenced 2,378 base pairs of the PRNP gene in 174 individuals; in addition, they genotyped two SNPs (or singl...Brain's own cannabis compound protects against inflammation
Some clinical studies have indicated that marijuana or its active cannabinoid ingredient alleviates symptoms of the inflammatory disease multiple sclerosis (MS). Also, researchers have found that the brain's natural "endocannabinoids" are released after brain injury and are believed to ...More evidence mammals, fruit flies share make-up on function of biological clocks
...w levels when Cry was over-produced. These results indicated that Cry normally inhibits clock gene expression in many clock cells ?just as it does in the mammalian clock. "In addition to finding a new function for Cryptochrome, the results reinforce that notion that fruit flies provide an excellent model fo...Hopkins study suggests commercially available antibiotic may help fight dementia in HIV patients
...treatment of bacterial infections. "These results indicated that this class of drugs may prove effective in treating HIV patients with dementia," Rumbaugh says. About 500,000 people in the United States alone have HIV dementia. And although new cases of HIV dementia have declined over the last 10 years (due ...Heat-shock protein vaccine reduces alveolar bone loss
...). Analysis of data from polymerase chain-reaction indicated that the vaccine successfully eradicated the multiple pathogenic species. The researchers concluded that P. gingivalis HSP60 could potentially be developed as a vaccine to inhibit periodontal disease induced by multiple pathogenic bacteria. ......of prostate tissue by Silverman and his colleagues indicated that the virus appears only in a small percentage of connective tissue cells, called stromal cells, rather than in the tumors themselves. "So, one interpretation could be that the infection is entirely incidental to prostate cancer," said Ganem. "The...