An essential regulator of body weight revealed
...nd maintained a normal body weight. Their findings indicated that if NPY/AgRP neurons are eliminated before they become fully functional, then animals somehow compensated, maintaining feeding behavior though some other mechanism. The compensatory mechanism persists, as animals treated with diphtheria toxin ear...K-State professors discover enzyme responsible for creation of a beetle's hard shell
...d of becoming hard and dark-colored. These results indicated which protein was responsible for the hard shell's formation, Kanost said. The identification of laccase-2 as the catalyst for cuticle tanning opens up possibilities of targeting this protein as a way of weakening the beetle's physical defenses agai...... at precisely the same times in both neurons, this indicated that they both shared the same inputs. The Salk scientists found that the thousands of neighboring neurons that make up these columns are not the same, and they often don't communicate directly with each other. In February, they reported in Nature h...War on terror meets war on cancer
...arly counterfeits had cotton that isotope analysis indicated was grown in a wet, cool climate, while later versions came from a dry, warm climate. That confirmed the government's belief the counterfeiters had ties with terrorists who moved from Eastern Europe to the Middle East. In 2000, the Drug Enforcement ...Delaware scientists make significant advance in study of small RNAs
...indings is the diversity." He said that their data indicated that the regions of the chromosomes where people had speculated there was not much transcriptional activity turned out to be sites of tremendous amounts of small RNA activity. Green said the implications of their findings would have a vital impact o...Center releases new public survey on stem cells
...e current policy or a complete ban of ESC research indicated that if the treatment scenario were to materialize, they would support a public policy for ESC research that is more supportive than their initial policy position. Similarly, if the alternative scenario were to materialize, 16 percent of respondents...Penn study finds direct role for glial cells in brain cross-talk
...ent research by Haydon and other investigators has indicated that glial cells do produce chemical transmitters called gliotransmitters and that these chemical signals are recognized by the neurons. The studies that have shown capability were conducted on isolated nerve cells or on slices of brain tissue. In t...'Perception' gene tracked humanity's evolution, scientists say
...tions in the gene. Past clinical studies have also indicated a positive correlation between lower prodynorphin levels in the brain and susceptibility to cocaine dependence. Matthew Rockman, David Goldstein and Gregory Wray (Duke University); Nicole Soranzo (University College London); and Fritz Zimprich (Med...Looking for the genes that affect a person's level of response to alcohol
...resting, said Schuckit, because prior research had indicated a potential link between this section of this chromosome and a person's alcohol response. "Researchers in San Francisco had previously carried out some research on worms," explained Schuckit, "finding that those worms with a mutation in that gene w...Key brain regulatory gene shows evolution in humans
... in the regulatory sequence leading to humans that indicated preservation due to positive evolutionary selection. They also found an "evolution-by-association," in which sequences near the regulatory segment showed greater mutational change -- as if they were "dragged along" with the evolving regulatory sequen...Tuberculosis still a risk for patients receiving HIV drugs
...hB, of the Desmond Tutu HIV Centre in South Africa indicated similar findings (unpublished) related to patients' immunological response to HAART and subsequent development of TB. The commentary concludes that HIV-infected patients' risk for infection with TB "remains elevated among those receiving treatment in...UCLA discovery will aid in treatment of patients with a deadly brain cancer
...am set out to find the molecular determinants that indicated which patients would respond best to EGFR blockers. Previous UCLA research in brain and other cancers suggested that the key might be the interaction of the PTEN protein and a mutant protein called EGFRvIII. About half of patients with amplified EGFR...No link found between caffeine intake and development of hypertension in women
...d financial impact. Several previous studies have indicated a possible association between caffeine intake and the risk of hypertension. Short-term studies have demonstrated that caffeine intake acutely increases blood pressure, but over time, weakening of this effect does occur. A long-term effect of caffei...Bacteria that cause tooth decay able to survive without important biochemical pathway
...thout this pathway; all of the existing literature indicated it is vital." The signal recognition particle, or SRP, pathway is a primary mechanism by which proteins are chaperoned from cellular assembly lines, where they are made, to the protective outer surface of the cells, where they are inserted. Without ...Argonne researchers confirm lead in Beethoven's illness
...etal section ?the top ?of the skull. "The testing indicated large amounts of lead in the Beethoven bone sample, compared to the control," said Bill Walsh, chief scientist at the Pfeiffer Treatment Center in Warrenville, Ill., and director of the Beethoven Research Project. The bone fragment is the property o...UCLA imaging study of children with autism finds broken mirror neuron system
... of the brain involving sight and facial movements indicated that the children with autism remained on task during the fMRI scans. ...Picking particles faster than one at a time
...n between manual selection and automatic selection indicated that 15 percent of the program's nominations were false positives, when the program was run again -- using a template after segmentation to filter out incompatible shapes -- false positives dropped to a mere 7 percent. Beyond the demonstrated goal ...HIV accessory protein disables host immunity via receptor-protein intermediary
...rom being made, Vpr did not kill host cells. "This indicated that glucocorticoid receptor function is not what's really necessary for Vpr activity," says Weiner. "The glucocorticoid receptor-Vpr complex must be interacting with something else." The team, led by first author Muthumani Karuppiah, PhD, Senior ......rhans histocytosis," said Dr. Merad. "Our findings indicated that finding ways to lower Csf-1 levels may produce new therapeutics for these patients." ...